TSH signalling and cancer. (Q30364765)

20 June 2017

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title

TSH signalling and cancer. (English)

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20 June 2017

2

Pilar Santisteban

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20 June 2017

author name string

Custodia García-Jiménez

series ordinal

1

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20 June 2017

language of work or name

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1 July 2007

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Arquivos Brasileiros de Endocrinologia e Metabologia

20 June 2017

published in

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20 June 2017

volume

51

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20 June 2017

issue

5

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20 June 2017

page(s)

654-671

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Fetal cell carcinogenesis of the thyroid: a hypothesis for better understanding of gene expression profile and genomic alternation in thyroid carcinoma

20 June 2017

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21 January 2018

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21 January 2018

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21 January 2018

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Minireview: thyrotropin receptor signaling in development and differentiation of the thyroid gland: insights from mouse models and human diseases

21 January 2018

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Thyrotropin potentiation of insulin-like growth factor-I dependent deoxribonucleic acid synthesis in FRTL-5 cells: mediation by an autocrine amplification factor(s).

21 January 2018

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From differentiation to proliferation: the secretory amyloid precursor protein as a local mediator of growth in thyroid epithelial cells

21 January 2018

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Thyrotropin (TSH)-induced production of vascular endothelial growth factor in thyroid cancer cells in vitro: evaluation of TSH signal transduction and of angiogenesis-stimulating growth factors

21 January 2018

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Role of insulin and serum on thyrotropin regulation of thyroid transcription factor-1 and pax-8 genes expression in FRTL-5 thyroid cells

21 January 2018

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Functional thyrotropin receptor attenuates malignant phenotype of follicular thyroid cancer cells

21 January 2018

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Molecular cloning of the thyrotropin receptor

21 January 2018

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Cloning, sequencing and expression of the human thyrotropin (TSH) receptor: evidence for binding of autoantibodies

21 January 2018

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Molecular cloning, sequence and functional expression of the cDNA for the human thyrotropin receptor

21 January 2018

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Cloning, sequencing and expression of human TSH receptor

21 January 2018

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Characterization of a thyroid hormone-mediated short-loop feedback control of TSH receptor gene in an anaplastic human thyroid cancer cell line

21 January 2018

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Collecting human spermatozoa onto filters for FISH. Application to the study of extreme oligozoospermia

21 January 2018

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Two-subunit structure of the human thyrotropin receptor

21 January 2018

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Processing of the precursors of the human thyroid-stimulating hormone receptor in various eukaryotic cells (human thyrocytes, transfected L cells and baculovirus-infected insect cells).

21 January 2018

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Shedding of human thyrotropin receptor ectodomain. Involvement of a matrix metalloprotease

21 January 2018

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Subunit structure of thyrotropin receptors expressed on the cell surface

21 January 2018

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The extracellular domain suppresses constitutive activity of the transmembrane domain of the human TSH receptor: implications for hormone-receptor interaction and antagonist design

21 January 2018

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Structural determinants for g protein activation and selectivity in the second intracellular loop of the thyrotropin receptor

21 January 2018

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Production of bioactive amino-terminal domain of the thyrotropin receptor via insertion in the plasma membrane by a glycosylphosphatidylinositol anchor

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Analysis of the thyrotropin receptor-thyrotropin interaction by comparative modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Ligand-dependent inhibition of oligomerization at the human thyrotropin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Intracellular entrapment of wild-type TSH receptor by oligomerization with mutants linked to dominant TSH resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

The TSH receptor reveals itself.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Repulsive separation of the cytoplasmic ends of transmembrane helices 3 and 6 is linked to receptor activation in a novel thyrotropin receptor mutant (M626I).

21 January 2018

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Implications for molecular mechanisms of glycoprotein hormone receptors using a new sequence-structure-function analysis resource

21 January 2018

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https://api.crossref.org/works/10.1590/S0004-27302007000500003

The human thyrotropin receptor is predominantly internalized by beta-arrestin 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Arrestin-mediated ERK activation by gonadotropin-releasing hormone receptors: receptor-specific activation mechanisms and compartmentalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Beta-arrestin signaling and regulation of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Upon thyrotropin binding the thyrotropin receptor is internalized and localized to endosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Thyrotropin receptor trafficking relies on the hScrib-betaPIX-GIT1-ARF6 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Absence of lutropin (LH) receptor mRNA in the rat thyroid: further evidence for specificity cross-over at the thyroid-stimulating hormone receptor level

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Insights into G protein structure, function, and regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families

21 January 2018

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https://api.crossref.org/works/10.1590/S0004-27302007000500003

Regulation of protein kinase C.

21 January 2018

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https://api.crossref.org/works/10.1590/S0004-27302007000500003

v-ras and protein kinase C dedifferentiate thyroid cells by down-regulating nuclear cAMP-dependent protein kinase A.

21 January 2018

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https://api.crossref.org/works/10.1590/S0004-27302007000500003

An adenosine derivative cooperates with TSH and Graves' IgG to induce Ca2 mobilization in single human thyroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Differential effect of thyroid-stimulating hormone (TSH) on intracellular free calcium and cAMP in cells transfected with the human TSH receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

A dominant negative Galphas mutant that prevents thyroid-stimulating hormone receptor activation of cAMP production and inositol 1,4,5-trisphosphate turnover: competition by different G proteins for activation by a common receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Increased cyclic adenosine 3',5'-monophosphate inhibits G protein-coupled activation of phospholipase C in rat FRTL-5 thyroid cells.

21 January 2018

1 reference

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Primary culture of cells from hyperfunctioning thyroid adenoma with an activating mutation of G alphas

21 January 2018

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Regulation of phosphoinositide-specific phospholipase C isozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Complexity and diversity of mammalian adenylyl cyclases

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Phosphoinositide 3-kinases: a conserved family of signal transducers

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Expression of G(alpha)(s) proteins and TSH receptor signalling in hyperfunctioning thyroid nodules with TSH receptor mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Cyclic nucleotide-gated ion channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A-mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Expression of the human TSH receptor in a human thyroid carcinoma cell line that lacks an endogenous TSH receptor: growth inhibition by cAMP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

A family of cAMP-binding proteins that directly activate Rap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Differential effects of protein kinase A on Ras effector pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

cAMP signaling selectively influences Ras effectors pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

BRAF mutations in papillary carcinomas of the thyroid

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Targeting the ERK pathway: novel therapeutics for thyroid cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

AKAP signalling complexes: focal points in space and time

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Selective modulation of protein kinase A I and II reveals distinct roles in thyroid cell gene expression and growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Mutations of the gene encoding the protein kinase A type I-alpha regulatory subunit in patients with the Carney complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

A dominant negative CREB (cAMP response element-binding protein) isoform inhibits thyrocyte growth, thyroid-specific gene expression, differentiation, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Role of the PKA-regulated transcription factor CREB in development and tumorigenesis of endocrine tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Expression of cAMP response element-binding protein and sodium iodide symporter in benign non-functioning and malignant thyroid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Multisite phosphorylation of the cAMP response element-binding protein (CREB) by a diversity of protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Decreased expression of thyrotropin receptor gene suggests a high-risk subgroup for oncocytic adenoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Mild congenital primary hypothyroidism in a Turkish family caused by a homozygous missense thyrotropin receptor (TSHR) gene mutation (A593 V).

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Somatic mutations in thyroid nodular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Germline mutations in the thyrotropin receptor gene cause non-autoimmune autosomal dominant hyperthyroidism

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Molecular insights into TSH receptor abnormality and thyroid disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Thyroid hyperfunctioning adenomas with and without Gsp/TSH receptor mutations show similar clinical features.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

TSH receptor mutation V509A causes familial hyperthyroidism by release of interhelical constraints between transmembrane helices TMH3 and TMH5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Molecular genetics of thyroid tumors and surgical decision-making

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

The human thyrotropin receptor is highly mutable: a review of gain-of-function mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Biological activity of activating thyrotrophin receptor mutants: modulation by iodide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Effects of mutations involving the highly conserved S281HCC motif in the extracellular domain of the thyrotropin (TSH) receptor on TSH binding and constitutive activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Autosomal-dominant non-autoimmune hyperthyroidism presenting with neuromuscular symptoms

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

A novel activating mutation in the thyrotropin receptor gene in an autonomously functioning thyroid nodule developed by a Japanese patient

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Premature birth and low birth weight associated with nonautoimmune hyperthyroidism due to an activating thyrotropin receptor gene mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Does a Leu 512 Arg thyrotropin receptor mutation cause an autonomously functioning papillary carcinoma?

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Sporadic congenital hyperthyroidism due to a germline mutation in the thyrotropin receptor gene (Leu 512 Gln) in a Japanese patient.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Novel thyrotropin receptor germline mutation (Ile568Val) in a Saxonian family with hereditary nonautoimmune hyperthyroidism

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Deletions in the third intracellular loop of the thyrotropin receptor. A new mechanism for constitutive activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Follicular carcinoma presenting as autonomous functioning thyroid nodule and containing an activating mutation of the TSH receptor (T620I) and a mutation of the Ki-RAS (G12C) genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Contrasting effects of activating mutations of GalphaS and the thyrotropin receptor on proliferation and differentiation of thyroid follicular cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Two novel mutations in the sixth transmembrane segment of the thyrotropin receptor gene causing hyperfunctioning thyroid nodules

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Mutations in the thyrotropin receptor signal transduction pathway in the hyperfunctioning thyroid nodules from multinodular goiters: a study in the Turkish population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

A novel activating mutation in transmembrane helix 6 of the thyrotropin receptor as cause of hereditary nonautoimmune hyperthyroidism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Two somatic TSH receptor mutations in a patient with toxic metastasising follicular thyroid carcinoma and non-functional lung metastases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Expression of beta-arrestins in toxic and cold thyroid nodules

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

TSH and cAMP do not signal mitogenesis through Ras activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Stimulation by thyroid-stimulating hormone and Grave's immunoglobulin G of vascular endothelial growth factor mRNA expression in human thyroid follicles in vitro and flt mRNA expression in the rat thyroid in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Graves' disease, thyroid nodules and thyroid cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

BRAF mediates RET/PTC-induced mitogen-activated protein kinase activation in thyroid cells: functional support for requirement of the RET/PTC-RAS-BRAF pathway in papillary thyroid carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Inhibitors of Raf kinase activity block growth of thyroid cancer cells with RET/PTC or BRAF mutations in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

How thyroid tumors start and why it matters: kinase mutants as targets for solid cancer pharmacotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Integrating signals between cAMP and the RAS/RAF/MEK/ERK signalling pathways. Based on the anniversary prize of the Gesellschaft für Biochemie und Molekularbiologie Lecture delivered on 5 July 2003 at the Special FEBS Meeting in Brussels

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Role of the different mitogen-activated protein kinase subfamilies in the stimulation of dog and human thyroid epithelial cell proliferation by cyclic adenosine 5'-monophosphate and growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

The Akt inhibitor KP372-1 suppresses Akt activity and cell proliferation and induces apoptosis in thyroid cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Mutation of the PIK3CA gene in anaplastic thyroid cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Gene methylation in thyroid tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Characterization of novel non-clonal intrachromosomal rearrangements between the H4 and PTEN genes (H4/PTEN) in human thyroid cell lines and papillary thyroid cancer specimens

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

CpG island methylation of tumor-related promoters occurs preferentially in undifferentiated carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Protein kinase A- and C-induced insulin release from Ca2 -insensitive pools

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

RAI(ShcC/N-Shc)-dependent recruitment of GAB 1 to RET oncoproteins potentiates PI 3-K signalling in thyroid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Nuclear localization of immunoreactive beta-catenin is specific to familial adenomatous polyposis in papillary thyroid carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Genetic alterations involved in the transition from well-differentiated to poorly differentiated and anaplastic thyroid carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase stabilizes beta-catenin through inhibition of its ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Lithium stimulates proliferation in cultured thyrocytes by activating Wnt/beta-catenin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Cyclin D1 overexpression in thyroid papillary microcarcinoma: its association with tumour size and aberrant beta-catenin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

A differential proteomic approach to identify proteins associated with thyroid cell transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

The Ras effector NORE1A is suppressed in follicular thyroid carcinomas with a PAX8-PPARgamma fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Lipid-dependent Targeting of G Proteins into Rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

Silencing of thePTENtumor-suppressor gene in anaplastic thyroid cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1590/S0004-27302007000500003

10.1590/S0004-27302007000500003

21 January 2018

Identifiers

DOI

1 reference

20 June 2017

1 reference