Pharmacokinetic and tumor distribution characteristics of temsirolimus in patients with recurrent malignant glioma. (Q30358123)

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30 December 2019

title

Pharmacokinetic and tumor distribution characteristics of temsirolimus in patients with recurrent malignant glioma (English)

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30 December 2019

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10

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30 December 2019

Lisa M DeAngelis

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3

Patrick Y Wen

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4

Timothy F Cloughesy

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16

Michael D Prados

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1

John G Kuhn

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Susan M Chang

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Karen L Fink

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13

Kenneth Hess

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30 December 2019

author name string

Harry Greenberg

5

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30 December 2019

David Schiff

6

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30 December 2019

Charles Conrad

7

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30 December 2019

H Ian Robins

9

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30 December 2019

Jeffrey Raizer

12

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Kathleen R Lamborn

14

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Janet Dancey

15

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30 December 2019

North American Brain Tumor Consortium and the National Cancer Institute

17

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30 December 2019

language of work or name

English

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publication date

1 December 2007

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30 December 2019

published in

Clinical Cancer Research

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30 December 2019

volume

13

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issue

24

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30 December 2019

page(s)

7401-7406

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In vitro metabolic study of temsirolimus: preparation, isolation, and identification of the metabolites

30 December 2019

cites work

1 reference

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Current development of mTOR inhibitors as anticancer agents

3 June 2018

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Recent developments in targeting the mammalian target of rapamycin (mTOR) kinase pathway

3 June 2018

1 reference

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Population pharmacokinetics of CCI-779: correlations to safety and pharmacogenomic responses in patients with advanced renal cancer

3 June 2018

1 reference

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Safety and pharmacokinetics of escalated doses of weekly intravenous infusion of CCI-779, a novel mTOR inhibitor, in patients with cancer

3 June 2018

1 reference

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Pten signaling in gliomas

3 June 2018

1 reference

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A phase I and pharmacokinetic study of temsirolimus (CCI-779) administered intravenously daily for 5 days every 2 weeks to patients with advanced cancer.

3 June 2018

1 reference

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Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme.

26 November 2018

1 reference

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Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: a North Central Cancer Treatment Group Study

26 November 2018

1 reference

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Phase I/pharmacokinetic study of CCI-779 in patients with recurrent malignant glioma on enzyme-inducing antiepileptic drugs.

26 November 2018

1 reference

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Is it important to correct apparent drug tissue concentrations for blood contamination in the dog?

26 November 2018

1 reference

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Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma

26 November 2018

1 reference

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Inhibition of the mammalian target of rapamycin sensitizes U87 xenografts to fractionated radiation therapy.

26 November 2018

1 reference

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PI 3-kinase, mTOR, protein synthesis and cancer

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918812

10.1158/1078-0432.CCR-07-0781

26 November 2018

Identifiers

DOI

1 reference

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30 December 2019

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30 December 2019

PubMed publication ID

18094423

1 reference