Leydig cells contribute to the inhibition of spermatogonial differentiation after irradiation of the rat. (Q30352913)

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11 March 2020

title

Leydig cells contribute to the inhibition of spermatogonial differentiation after irradiation of the rat (English)

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11 March 2020

1

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11 March 2020

author name string

W Zhou

2

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11 March 2020

C C Y Weng

3

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11 March 2020

S H Shao

4

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11 March 2020

M L Meistrich

5

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11 March 2020

publication date

18 March 2016

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11 March 2020

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volume

4

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issue

3

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11 March 2020

page(s)

412-424

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Autocrine androgen action is essential for Leydig cell maturation and function, and protects against late-onset Leydig cell apoptosis in both mice and men.

11 March 2020

cites work

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Effects of multiple doses of cyclophosphamide on mouse testes: Accessing the germ cells lost, and the functional damage of stem cells

3 June 2018

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Stem Leydig cell differentiation: gene expression during development of the adult rat population of Leydig cells

3 June 2018

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Androgen Suppression-Induced Stimulation of Spermatogonial Differentiation in Juvenile Spermatogonial Depletion Mice Acts by Elevating the Testicular Temperature

3 June 2018

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Estrogen-regulated genes in rat testes and their relationship to recovery of spermatogenesis after irradiation.

3 June 2018

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Activin bioactivity affects germ cell differentiation in the postnatal mouse testis in vivo

3 June 2018

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Changes in gene expression in somatic cells of rat testes resulting from hormonal modulation and radiation-induced germ cell depletion

3 June 2018

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Stage-specific gene expression is a fundamental characteristic of rat spermatogenic cells and Sertoli cells

3 June 2018

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Leydig cell re-generation and expression of cell signaling molecules in the germ cell-free testis

3 June 2018

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p53-dependent apoptosis in the inhibition of spermatogonial differentiation in juvenile spermatogonial depletion (Utp14bjsd) mice

3 June 2018

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In search of rat stem Leydig cells: identification, isolation, and lineage-specific development.

3 June 2018

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Inhibition of spermatogonial differentiation by testosterone

3 June 2018

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2,5-hexanedione-induced testicular injury

3 June 2018

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GnRH analog, leuprorelin acetate, promotes regeneration of rat spermatogenesis after severe chemical damage

3 June 2018

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Chemical synthesis and biological activity of rat INSL3.

3 June 2018

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Leydig cell resistance to the cytotoxic effect of ethylene dimethanesulphonate in the adult rat testis.

3 June 2018

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Re-evaluation of the intratesticular level of testosterone required for quantitative maintenance of spermatogenesis in the rat.

3 June 2018

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Inhibin secretion is influenced by Leydig cells: evidence from studies using the cytotoxin ethane dimethane sulphonate (EDS).

3 June 2018

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[Reversible germ cell toxicity following aggressive chemotherapy in patients with testicular tumors: results of a prospective study].

3 June 2018

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2,5-hexanedione exposure in the rat results in long-term testicular atrophy despite the presence of residual spermatogonia.

3 June 2018

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Induction of apoptosis in the germ cells of adult male rats after exposure to cyclophosphamide

3 June 2018

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Immunohistochemical evaluation of the cellular localization and ontogeny of 3β-hydroxysteroid dehydrogenase/delta 5-4 isomerase in the human fetal adrenal gland

21 January 2018

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Testicular edema is associated with spermatogonial arrest in irradiated rats

21 January 2018

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Estrogen enhances recovery from radiation-induced spermatogonial arrest in rat testes

21 January 2018

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Defining the cellular and molecular mechanisms of toxicant action in the testis

21 January 2018

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Reduction of long-term effects of local heating of the testis by treatment of rats with a GnRH agonist and an anti-androgen

21 January 2018

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Inhibition of recovery of spermatogenesis in irradiated rats by different androgens.

21 January 2018

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Both testosterone and follicle-stimulating hormone independently inhibit spermatogonial differentiation in irradiated rats.

21 January 2018

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Evaluation of relative roles of LH and FSH in regulation of differentiation of Leydig cells using an ethane 1,2-dimethylsulfonate-treated adult rat model

21 January 2018

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The radiation-induced block in spermatogonial differentiation is due to damage to the somatic environment, not the germ cells

21 January 2018

1 reference

Repopulation of Leydig Cells in Mature Rats after Selective Destruction of the Existent Leydig Cells with Ethylene Dimethane Sulfonate Is Dependent on Luteinizing Hormone and Not Follicle-Stimulating Hormone

21 January 2018

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GnRH agonists and antagonists stimulate recovery of fertility in irradiated LBNF1 rats.

21 January 2018

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Leuprolide, a Gonadotropin-Releasing Hormone Agonist, Reestablishes Spermatogenesis After 2,5-Hexanedione-Induced Irreversible Testicular Injury in the Rat, Resulting in Normalized Stem Cell Factor Expression*

26 November 2018

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Differential regulation of steroidogenic enzymes during differentiation optimizes testosterone production by adult rat Leydig cells

26 November 2018

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Immunohistochemical localization of androgen receptors in the rat testis: evidence for stage-dependent expression and regulation by androgens

26 November 2018

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The effect of testicular x-irradiation on spermatogenesis in man. A comparison with the mouse

26 November 2018

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12 December 2020

Comparative protective actions of gonadotrophins and testosterone against the antispermatogenic action of ethane dimethanesulphonate

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12 December 2020

Dose and time relationships in the endocrine response of the irradiated adult rat testis

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12 December 2020

Origin of regenerating Leydig cells in the testis of the adult rat. An ultrastructural, morphometric and hormonal assay study

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12 December 2020

Identification of two testosterone-responsive testicular proteins in Sertoli cell-enriched culture medium whose secretion is suppressed by cells of the intact seminiferous tubule

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12 December 2020

Assessment of the role of Leydig cell products other than testosterone in spermatogenesis and fertility in adult rats

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12 December 2020

The regulation of the proliferation and differentiation of rat Leydig cell precursor cells after EDS administration or daily HCG treatment

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12 December 2020

Maintenance of advanced spermatogenic cells in the adult rat testis: quantitative relationship to testosterone concentration within the testis

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12 December 2020

Stimulation of the proliferation and differentiation of Leydig cell precursors after the destruction of existing Leydig cells with ethane dimethyl sulphonate (EDS) can take place in the absence of LH

1 reference

12 December 2020

Does ethane 1,2-dimethanesulphonate (EDS) have a direct cytotoxic effect on the seminiferous epithelium of the rat testis?

1 reference

12 December 2020

Stem Cell Kinetics in Rat Testis after Irreversible Injury Induced by 2,5-Hexanedione1

1 reference

12 December 2020

Hormonal protection from cyclophosphamide-induced inactivation of rat stem spermatogonia

1 reference

12 December 2020

Failure of spermatogenesis to recover despite the presence of a spermatogonia in the irradiated LBNF1 rat

1 reference

12 December 2020

Hormone treatment after irradiation stimulates recovery of rat spermatogenesis from surviving spermatogonia

1 reference

12 December 2020

Identification of Markers for Precursor and Leydig Cell Differentiation in the Adult Rat Testis Following Ethane Dimethyl Sulphonate Administration1

1 reference

12 December 2020

Hormonal treatment after cytotoxic therapy stimulates recovery of spermatogenesis

1 reference

12 December 2020

Cisplatin-induced long-term failure of spermatogenesis in adult C57/Bl/6J mice

1 reference

12 December 2020

Donor Sertoli cells transplanted into irradiated rat testes stimulate partial recovery of endogenous spermatogenesis

1 reference

12 December 2020

Enhancement of A spermatogonial proliferation and differentiation in irradiated rats by gonadotropin-releasing hormone antagonist administration

1 reference

12 December 2020

Gonadotropin-releasing hormone analogs stimulate and testosterone inhibits the recovery of spermatogenesis in irradiated rats

1 reference

12 December 2020

Regulatory influence of germ cells on sertoli cell function in the pre-pubertal rat after acute irradiation of the testis

1 reference

12 December 2020

Identifiers

DOI

10.1111/ANDR.12168

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26991593 AND SRC:MED&resulttype=core&format=json

11 March 2020

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11 March 2020

PubMed publication ID

26991593

1 reference