G protein signaling: insights from new structures. (Q30336443)

19 June 2017

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title

G protein signaling: insights from new structures. (English)

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19 June 2017

Anita M Preininger

1

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19 June 2017

Heidi E Hamm

series ordinal

2

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19 June 2017

language of work or name

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27 January 2004

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Science's STKE : signal transduction knowledge environment

19 June 2017

published in

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19 June 2017

volume

2004

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19 June 2017

issue

218

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19 June 2017

page(s)

re3

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G protein mechanisms: insights from structural analysis

19 June 2017

cites work

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https://api.crossref.org/works/10.1126/STKE.2182004RE3

Crystal structure of rhodopsin: A G protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

The 2.2 A crystal structure of transducin-alpha complexed with GTP gamma S

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

The 2.0 A crystal structure of a heterotrimeric G protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

GTPase mechanism of Gproteins from the 1.7-A crystal structure of transducin alpha-GDP-AIF-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

The A326S mutant of Gialpha1 as an approximation of the receptor-bound state

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Modulation of the affinity and selectivity of RGS protein interaction with G alpha subunits by a conserved asparagine/serine residue

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Structure and function in rhodopsin: mapping light-dependent changes in distance between residue 316 in helix 8 and residues in the sequence 60-75, covering the cytoplasmic end of helices TM1 and TM2 and their connection loop CL1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Structure and function in rhodopsin: mapping light-dependent changes in distance between residue 65 in helix TM1 and residues in the sequence 306-319 at the cytoplasmic end of helix TM7 and in helix H8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

How activated receptors couple to G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Conformational changes in the amino-terminal helix of the G protein alpha(i1) following dissociation from Gbetagamma subunit and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Structure and orientation of a G protein fragment in the receptor bound state from residual dipolar couplings

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Mapping of contact sites in complex formation between transducin and light-activated rhodopsin by covalent crosslinking: use of a photoactivatable reagent

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Identification of effector residues on photoreceptor G protein, transducin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

The carboxyl terminus of the gamma-subunit of rod cGMP phosphodiesterase contains distinct sites of interaction with the enzyme catalytic subunits and the alpha-subunit of transducin

21 January 2018

1 reference

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Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gbetagamma

21 January 2018

1 reference

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G protein-coupled receptor Kinase 2/G alpha q/11 interaction. A novel surface on a regulator of G protein signaling homology domain for binding G alpha subunits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Co-expression of Gbeta5 enhances the function of two Ggamma subunit-like domain-containing regulators of G protein signaling proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

A beta2 adrenergic receptor signaling complex assembled with the Ca2 channel Cav1.2

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

G protein-coupled receptors form stable complexes with inwardly rectifying potassium channels and adenylyl cyclase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Tertiary and quaternary structural changes in Gi alpha 1 induced by GTP hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

A unique fold of phospholipase C-beta mediates dimerization and interaction with G alpha q

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Rapid GTP binding and hydrolysis by G(q) promoted by receptor and GTPase-activating proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Oligomerization of G-protein-coupled transmitter receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Atomic structure of PDE4: insights into phosphodiesterase mechanism and specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Structure of the rgRGS domain of p115RhoGEF

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Comparison of DNA sequences with protein sequences.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Structural requirements for the stabilization of metarhodopsin II by the C terminus of the alpha subunit of transducin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Mutational analysis of functional interfaces of transducin

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Substitution of transducin ser202 by asp abolishes G-protein/RGS interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Evidence for structural changes in carboxyl-terminal peptides of transducin alpha-subunit upon binding a soluble mimic of light-activated rhodopsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Mapping of effector binding sites of transducin alpha-subunit using G alpha t/G alpha i1 chimeras

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

A site on rod G protein alpha subunit that mediates effector activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

The alpha-helical domain of Galphat determines specific interaction with regulator of G protein signaling 9

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

Rhodopsin recognition by mutant G(s)alpha containing C-terminal residues of transducin

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/STKE.2182004RE3

21 January 2018

Identifiers

DOI

10.1126/STKE.2182004RE3

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19 June 2017

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