Obesity-related glomerulopathy: clinical and pathologic characteristics and pathogenesis. (Q30249819)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27263398 AND SRC:MED&resulttype=core&format=json

12 March 2020

review article

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title

Obesity-related glomerulopathy: clinical and pathologic characteristics and pathogenesis (English)

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12 March 2020

0 references

1 reference

Vivette D D'Agati

1

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12 March 2020

Avry Chagnac

2

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12 March 2020

Moshe Levi

4

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12 March 2020

Michal Herman-Edelstein

6

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12 March 2020

Manuel Praga

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12 March 2020

language of work or name

English

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publication date

6 June 2016

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Nature Reviews Nephrology

12 March 2020

published in

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12 March 2020

volume

12

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12 March 2020

issue

8

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12 March 2020

page(s)

453-471

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Prevalence of chronic kidney disease in the United States

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31 March 2020

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https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Independent influence of dietary protein on markers of kidney function and disease in obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

The metabolic syndrome and chronic kidney disease in U.S. adults

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

The renin-angiotensin-aldosterone system in podocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Differential impacts of adiponectin on low-grade albuminuria between obese and nonobese persons without diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Postglomerular vascular protein concentration: evidence for a causal role in governing fluid reabsorption and glomerulotubular balance by the renal proximal tubule

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Effect of increased peritubule protein concentration on proximal tubule reabsorption in the presence and absence of extracellular volume expansion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Mechanism of glomerulotubular balance in the setting of heterogeneous glomerular injury. Preservation of a close functional linkage between individual nephrons and surrounding microvasculature

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Mechanotransduction in the renal tubule

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

A potential role for mechanical forces in the detachment of podocytes and the progression of CKD.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Increased urine podocyte-associated messenger RNAs in severe obesity are evidence of podocyte injury.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Proximal tubular hypertrophy and enlarged glomerular and proximal tubular urinary space in obese subjects with proteinuria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Adipokines in inflammation and metabolic disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Adipose tissue angiogenesis as a therapeutic target for obesity and metabolic diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Medicine. Can we nip obesity in its vascular bud?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome--an allostatic perspective

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Adipokines as a link between obesity and chronic kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

The mesangial cell revisited: no cell is an island

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Vascular factors altered in glucose-treated mesangial cells and diabetic glomeruli. Changes in vascular factors impair endothelial cell growth and matrix

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Early systemic microvascular damage in pigs with atherogenic diabetes mellitus coincides with renal angiopoietin dysbalance.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Cathepsin S Cleavage of Protease-Activated Receptor-2 on Endothelial Cells Promotes Microvascular Diabetes Complications.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

A central body fat distribution is related to renal function impairment, even in lean subjects

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Waist-to-hip ratio, body mass index, and subsequent kidney disease and death.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Differential responses of visceral and subcutaneous fat depots to nutrients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Metabolic syndrome and the risk for chronic kidney disease among nondiabetic adults

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Association of visceral and subcutaneous adiposity with kidney function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

A possible role of cystatin C in adipose tissue homeostasis may impact kidney function estimation in metabolic syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Abdominal obesity and metabolic syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

The role of hepatokines in metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Association of non-alcoholic fatty liver disease with chronic kidney disease: a systematic review and meta-analysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Metabolic imaging of human kidney triglyceride content: reproducibility of proton magnetic resonance spectroscopy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

SP113IMAGING FATTY KIDNEY USING PROTON MR SPECTROSCOPY: VALIDATION BY PORCINE KIDNEY BIOPSIES

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

IGF-1-induced lipid accumulation impairs mesangial cell migration and contractile function.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Dysregulation of LDL receptor under the influence of inflammatory cytokines: a new pathway for foam cell formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Mesangial cells defy LDL receptor paradigm

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Increased glomerular filtration rate in early metabolic syndrome is associated with renal adiposity and microvascular proliferation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Albumin-associated free fatty acids induce macropinocytosis in podocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

An update on the lipid nephrotoxicity hypothesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Smad3 deficiency protects mice from obesity-induced podocyte injury that precedes insulin resistance.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Transforming growth factor-beta/Smad3 signaling regulates insulin gene transcription and pancreatic islet beta-cell function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Protection from obesity and diabetes by blockade of TGF-β/Smad3 signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Substrate-utilization of the Human Kidney

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

The evolving understanding of the contribution of lipid metabolism to diabetic kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Ectopic fat in insulin resistance, dyslipidemia, and cardiometabolic disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Banting lecture 1988. Role of insulin resistance in human disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Fasting insulin modifies the relation between age and renal function.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Glomerular hyperfiltration: a new marker of metabolic risk

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Insulin's acute effects on glomerular filtration rate correlate with insulin sensitivity whereas insulin's acute effects on proximal tubular sodium reabsorption correlation with salt sensitivity in normal subjects.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Insulin signalling to the kidney in health and disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Regulation of podocyte survival and endoplasmic reticulum stress by fatty acids

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Insulin signaling to the glomerular podocyte is critical for normal kidney function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

AKT2 is essential to maintain podocyte viability and function during chronic kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Insulin directly stimulates VEGF-A production in the glomerular podocyte

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

mTOR signaling in growth control and disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Deletion of the insulin receptor in the proximal tubule promotes hyperglycemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Metabolic substrates, cellular energy production, and the regulation of proximal tubular transport

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Role of the kidney in normal glucose homeostasis and in the hyperglycaemia of diabetes mellitus: therapeutic implications

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Glucose control by the kidney: an emerging target in diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Glomerular-specific protein kinase C-β-induced insulin receptor substrate-1 dysfunction and insulin resistance in rat models of diabetes and obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Sterol regulatory element-binding proteins: transcriptional activators of lipid synthesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Joe Goldstein and Mike Brown: from cholesterol homeostasis to new paradigms in membrane biology

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Direct binding of cholesterol to the purified membrane region of SCAP: mechanism for a sterol-sensing domain

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Medicine. HDL miR-ed down by SREBP introns

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

The Scap/SREBP pathway is essential for developing diabetic fatty liver and carbohydrate-induced hypertriglyceridemia in animals

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Role of sterol regulatory element-binding protein 1 in regulation of renal lipid metabolism and glomerulosclerosis in diabetes mellitus.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Regulation of lipoprotein trafficking in the kidney: role of inflammatory mediators and transcription factors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Regulation of renal lipid metabolism, lipid accumulation, and glomerulosclerosis in FVBdb/db mice with type 2 diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Diet-induced obesity in C57BL/6J mice causes increased renal lipid accumulation and glomerulosclerosis via a sterol regulatory element-binding protein-1c-dependent pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Role of altered renal lipid metabolism and the sterol regulatory element binding proteins in the pathogenesis of age-related renal disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Calorie restriction modulates renal expression of sterol regulatory element binding proteins, lipid accumulation, and age-related renal disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Lipid accumulation and transforming growth factor-beta upregulation in the kidneys of rats administered angiotensin II.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in Akita and OVE26 mice with type 1 diabetes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Role of altered renal lipid metabolism in the development of renal injury induced by a high-fat diet

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

D-4F reduces EO6 immunoreactivity, SREBP-1c mRNA levels, and renal inflammation in LDL receptor-null mice fed a Western diet

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

In vivo and in vitro effects of SREBP-1 on diabetic renal tubular lipid accumulation and RNAi-mediated gene silencing study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Structural and functional changes in the kidneys of high-fat diet-induced obese mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Omacor, n-3 polyunsaturated fatty acid, attenuated albuminuria and renal dysfunction with decrease of SREBP-1 expression and triglyceride amount in the kidney of type II diabetic animals

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

SREBP-1 Mediates Angiotensin II-Induced TGF-β1 Upregulation and Glomerular Fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

SREBP-1 is a novel mediator of TGFβ1 signaling in mesangial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

SREBP-1 activation by glucose mediates TGF-β upregulation in mesangial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

PI3K/Akt pathway mediates high glucose-induced lipogenesis and extracellular matrix accumulation in HKC cells through regulation of SREBP-1 and TGF-β1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

IFN-γ induces lipogenesis in mouse mesangial cells via the JAK2/STAT1 pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Phospho-mTOR: a novel target in regulation of renal lipid metabolism abnormality of diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Co-regulation of SREBP-1 and mTOR ameliorates lipid accumulation in kidney of diabetic mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Phospho-GSK-3β is involved in the high-glucose-mediated lipid deposition in renal tubular cells in diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

PTEN ameliorates high glucose-induced lipid deposits through regulating SREBP-1/FASN/ACC pathway in renal proximal tubular cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Farnesoid X receptor modulates renal lipid metabolism, fibrosis, and diabetic nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

The farnesoid X receptor modulates renal lipid metabolism and diet-induced renal inflammation, fibrosis, and proteinuria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Diabetic nephropathy is accelerated by farnesoid X receptor deficiency and inhibited by farnesoid X receptor activation in a type 1 diabetes model

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Effect of chenodeoxycholic acid on fibrosis, inflammation and oxidative stress in kidney in high-fructose-fed Wistar rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Vitamin D receptor agonist doxercalciferol modulates dietary fat-induced renal disease and renal lipid metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Altered renal lipid metabolism and renal lipid accumulation in human diabetic nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Fenofibrate, a PPARα agonist, has renoprotective effects in mice by enhancing renal lipolysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Fenofibrate improves renal lipotoxicity through activation of AMPK-PGC-1α in db/db mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Fenofibrate attenuates tubulointerstitial fibrosis and inflammation through suppression of nuclear factor-κB and transforming growth factor-β1/Smad3 in diabetic nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Fibrates: therapeutic potential for diabetic nephropathy?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Fenofibrate reduces progression to microalbuminuria over 3 years in a placebo-controlled study in type 2 diabetes: results from the Diabetes Atherosclerosis Intervention Study (DAIS).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Effects of fenofibrate on renal function in patients with type 2 diabetes mellitus: the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Effects of combination lipid therapy in type 2 diabetes mellitus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Metformin decreases high-fat diet-induced renal injury by regulating the expression of adipokines and the renal AMP-activated protein kinase/acetyl-CoA carboxylase pathway in mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Regulation of lipid accumulation by AMP-activated kinase [corrected] in high fat diet-induced kidney injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

G Protein-Coupled Bile Acid Receptor TGR5 Activation Inhibits Kidney Disease in Obesity and Diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Dysregulation of low-density lipoprotein receptor contributes to podocyte injuries in diabetic nephropathy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

ER stress contributes to renal proximal tubule injury by increasing SREBP-2-mediated lipid accumulation and apoptotic cell death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Advanced glycation end products (AGEs) increase human mesangial foam cell formation by increasing Golgi SCAP glycosylation in vitro

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Effect and mechanism of the Ang-(1-7) on human mesangial cells injury induced by low density lipoprotein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Anti-Inflammatory Effects of Ang-(1-7) in Ameliorating HFD-Induced Renal Injury through LDLr-SREBP2-SCAP Pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Effects of hydrophilic statins on renal tubular lipid accumulation in diet-induced obese mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Liver X receptors in lipid metabolism: opportunities for drug discovery

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Liver X receptor-alpha mediates cholesterol efflux in glomerular mesangial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Cyclodextrin protects podocytes in diabetic kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Diabetes reduces the cholesterol exporter ABCA1 in mouse macrophages and kidneys

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Downregulation of liver X receptor-alpha in mouse kidney and HK-2 proximal tubular cells by LPS and cytokines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Activation of liver X receptor inhibits osteopontin and ameliorates diabetic nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Lipid Droplet Accumulation Is Associated with an Increase in Hyperglycemia-Induced Renal Damage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Liver X receptors preserve renal glomerular integrity under normoglycaemia and in diabetes in mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Liver X receptors alpha and beta regulate renin expression in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Activation of liver X receptor-alpha reduces activation of the renal and cardiac renin-angiotensin-aldosterone system

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Liver X receptor agonists decrease ENaC-mediated sodium transport in collecting duct cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Activation of liver X receptors reduces CFTR-mediated Cl(-) transport in kidney collecting duct cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Errors induced by indexing glomerular filtration rate for body surface area: reductio ad absurdum

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2016.75

Functional and structural changes in the kidney in the early stages of obesity

31 March 2020

1 reference

12 December 2020

Overweight/obesity revisited as a predictive risk factor in primary IgA nephropathy

1 reference

12 December 2020

Role of nitric oxide in modulating renal function and arterial pressure during chronic aldosterone excess

1 reference

12 December 2020

Adjustable gastric banding and conventional therapy for type 2 diabetes: a randomized controlled trial

1 reference

12 December 2020

Glomerular hyperfiltration in experimental diabetes mellitus: potential role of tubular reabsorption

1 reference

12 December 2020

Structure-stabilizing forces in the glomerular tuft.

1 reference

12 December 2020

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013

1 reference

12 December 2020

The effect of bariatric surgery on renal function and disease: a focus on outcomes and inflammation.

1 reference

12 December 2020

Microalbuminuria in obese patients with or without hypertension

1 reference

12 December 2020

Acute effect of a soy protein-rich meal-replacement application on renal parameters in patients with the metabolic syndrome.

1 reference

12 December 2020

Effects of glomerular filtration dynamics on the glomerular permeability coefficient.

1 reference

12 December 2020

Effects of physiological hyperinsulinemia on systemic, renal, and hepatic substrate metabolism

1 reference

12 December 2020

Central obesity and hypertension: pathophysiologic role of renal haemodynamics and function

1 reference

12 December 2020

Lipid mediators of inflammation in obesity-related glomerulopathy

1 reference

12 December 2020

Massive obesity and the kidney. A morphologic and statistical study

1 reference

12 December 2020

Renal lipid metabolism

1 reference

12 December 2020

Hemodynamic effects of angiotensin II in the kidney

1 reference

12 December 2020

Hormonal interactions with the proximal Na( )-H exchanger

1 reference

12 December 2020

Adiponectin regulates albuminuria and podocyte function in mice

1 reference

12 December 2020

Effect of fenofibrate on progression of coronary-artery disease in type 2 diabetes: the Diabetes Atherosclerosis Intervention Study, a randomised study

1 reference

12 December 2020

Dietary protein and renal function

1 reference

12 December 2020

Effect of diet on creatinine clearance and excretion in young and elderly healthy subjects and in patients with renal disease

1 reference

12 December 2020

Effects of adiponectin on the renal sympathetic nerve activity and blood pressure in rats

1 reference

12 December 2020

Renal haemodynamic studies in obesity hypertension.

1 reference

12 December 2020

HMGB1/SREBP-1 mediated IFN-gamma-induced lipid deposition in mouse mesangial cells

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRNEPH.2016.75

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27263398 AND SRC:MED&resulttype=core&format=json

12 March 2020

1 reference