Vav1 and vav3 have critical but redundant roles in mediating platelet activation by collagen. (Q30163810)

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3 January 2020

title

Vav1 and vav3 have critical but redundant roles in mediating platelet activation by collagen (English)

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2

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3 January 2020

Martin Turner

4

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3 January 2020

Steve P. Watson

5

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3 January 2020

author name string

Andrew C Pearce

1

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3 January 2020

Daniel D Billadeau

3

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3 January 2020

Elena Vigorito

6

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language of work or name

English

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publication date

27 September 2004

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Journal of Biological Chemistry

3 January 2020

published in

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3 January 2020

volume

279

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issue

52

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page(s)

53955-53962

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The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen

3 January 2020

cites work

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https://api.crossref.org/works/10.1074/JBC.M410355200

Collagen receptor signalling in platelets: extending the role of the ITAM.

21 January 2018

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The contribution of glycoprotein VI to stable platelet adhesion and thrombus formation illustrated by targeted gene deletion

21 January 2018

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LAT is required for tyrosine phosphorylation of phospholipase cgamma2 and platelet activation by the collagen receptor GPVI.

21 January 2018

1 reference

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Differential requirement for LAT and SLP-76 in GPVI versus T cell receptor signaling

21 January 2018

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The role of the adapter molecule SLP-76 in platelet function

21 January 2018

1 reference

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Tec regulates platelet activation by GPVI in the absence of Btk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M410355200

Murine GPVI stimulates weak integrin activation in PLCgamma2-/- platelets: involvement of PLCgamma1 and PI3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M410355200

A PLC gamma 2-independent platelet collagen aggregation requiring functional association of GPVI and integrin alpha2beta1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M410355200

Vav1, but not Vav2, contributes to platelet aggregation by CRP and thrombin, but neither is required for regulation of phospholipase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M410355200

Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins

21 January 2018

1 reference

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Identification of VAV2 on 9q34 and its exclusion as the tuberous sclerosis gene TSC1

21 January 2018

1 reference

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Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2

21 January 2018

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Regulatory and signaling properties of the Vav family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M410355200

VAV proteins as signal integrators for multi-subunit immune-recognition receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M410355200

The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-kappaB pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M410355200

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M410355200

Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M410355200

Vav3 modulates B cell receptor responses by regulating phosphoinositide 3-kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M410355200

Vav1/2/3-null Mice Define an Essential Role for Vav Family Proteins in Lymphocyte Development and Activation but a Differential Requirement in MAPK Signaling in T and B Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M410355200

Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M410355200

Pleiotropic defects in TCR signaling in a Vav-1-null Jurkat T-cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M410355200

The Rho family guanine nucleotide exchange factor Vav-2 regulates the development of cell-mediated cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M410355200

GPVI levels in platelets: relationship to platelet function at high shear

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M410355200

Phosphatidylinositol 3,4,5-trisphosphate regulates Ca(2 ) entry via btk in platelets and megakaryocytes without increasing phospholipase C activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M410355200

CD19 as a membrane-anchored adaptor protein of B lymphocytes: costimulation of lipid and protein kinases by recruitment of Vav.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M410355200

Vav1 transduces T cell receptor signals to the activation of phospholipase C-gamma1 via phosphoinositide 3-kinase-dependent and -independent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M410355200

Regulation of blood and lymphatic vascular separation by signaling proteins SLP-76 and Syk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M410355200

Vav1 Transduces T Cell Receptor Signals to the Activation of the Ras/ERK Pathway via LAT, Sos, and RasGRP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M410355200

Signal transduction through Vav-2 participates in humoral immune responses and B cell maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M410355200

21 January 2018

Identifiers

DOI

10.1074/JBC.M410355200

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15456756 AND SRC:MED&resulttype=core&format=json

3 January 2020

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