Lipopolysaccharide-induced NF-κB nuclear translocation is primarily dependent on MyD88, but TNFα expression requires TRIF and MyD88 (Q29994846)

28469251

27 June 2017

title

Lipopolysaccharide-induced NF-κB nuclear translocation is primarily dependent on MyD88, but TNFα expression requires TRIF and MyD88 (English)

1 reference

27 June 2017

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1

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9 June 2020

John A Wright

3

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9 June 2020

Iain Fraser

7

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9 June 2020

author name string

Eugenia Cammarota

2

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9 June 2020

Pietro Cicuta

4

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9 June 2020

Rachel A Gottschalk

5

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9 June 2020

Ning Li

6

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9 June 2020

Clare E Bryant

8

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9 June 2020

language of work or name

English

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publication date

3 May 2017

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27 June 2017

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volume

7

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issue

1

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9 June 2020

page(s)

1428

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Creative Commons Attribution 4.0 International

9 June 2020

copyright license

start time

3 May 2017

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

1 reference

https://api.crossref.org/works/10.1038/S41598-017-01600-Y

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

22 May 2017

1 reference

https://api.crossref.org/works/10.1038/S41598-017-01600-Y

MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4

22 May 2017

1 reference

https://api.crossref.org/works/10.1038/S41598-017-01600-Y

The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

22 May 2017

1 reference

https://api.crossref.org/works/10.1038/S41598-017-01600-Y

Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling

22 May 2017

1 reference

https://api.crossref.org/works/10.1038/S41598-017-01600-Y

Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling

22 May 2017

1 reference

https://api.crossref.org/works/10.1038/S41598-017-01600-Y

CD14 controls the LPS-induced endocytosis of Toll-like receptor 4

22 May 2017

1 reference

https://api.crossref.org/works/10.1038/S41598-017-01600-Y

LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

22 May 2017

1 reference

https://api.crossref.org/works/10.1038/S41598-017-01600-Y

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta

22 May 2017

1 reference

https://api.crossref.org/works/10.1038/S41598-017-01600-Y

TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

22 May 2017

1 reference

https://api.crossref.org/works/10.1038/S41598-017-01600-Y

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

22 May 2017

1 reference

https://api.crossref.org/works/10.1038/S41598-017-01600-Y

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

22 May 2017

1 reference

https://api.crossref.org/works/10.1038/S41598-017-01600-Y

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

22 May 2017

1 reference

https://api.crossref.org/works/10.1038/S41598-017-01600-Y

22 May 2017

Signaling to NF-kappaB

1 reference

https://api.crossref.org/works/10.1038/S41598-017-01600-Y

Oscillations in NF-kappaB signaling control the dynamics of gene expression

22 May 2017

1 reference

https://api.crossref.org/works/10.1038/S41598-017-01600-Y

High-throughput analysis of NF-κB dynamics in single cells reveals basal nuclear localization of NF-κB and spontaneous activation of oscillations

22 May 2017

1 reference

https://api.crossref.org/works/10.1038/S41598-017-01600-Y

Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades

22 May 2017

1 reference

https://api.crossref.org/works/10.1038/S41598-017-01600-Y

Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states

22 May 2017

1 reference

https://api.crossref.org/works/10.1038/S41598-017-01600-Y

Distinct NF-κB and MAPK Activation Thresholds Uncouple Steady-State Microbe Sensing from Anti-pathogen Inflammatory Responses.

22 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

High-Content Quantification of Single-Cell Immune Dynamics.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

NF-κB oscillations translate into functionally related patterns of gene expression.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

A Single Bacterial Immune Evasion Strategy Dismantles Both MyD88 and TRIF Signaling Pathways Downstream of TLR4

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

Distinct single-cell signaling characteristics are conferred by the MyD88 and TRIF pathways during TLR4 activation.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

Assembly and localization of Toll-like receptor signalling complexes.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

TLR2 and TLR4 signaling pathways are required for recombinant Brucella abortus BCSP31-induced cytokine production, functional upregulation of mouse macrophages, and the Th1 immune response in vivo and in vitro

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

Switching of the relative dominance between feedback mechanisms in lipopolysaccharide-induced NF-κB signaling

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

Signaling of high mobility group box 1 (HMGB1) through toll-like receptor 4 in macrophages requires CD14.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

TRIF mediates Toll-like receptor 2-dependent inflammatory responses to Borrelia burgdorferi

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

Quantitative measurement of single cell dynamics.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

Physiological levels of TNFalpha stimulation induce stochastic dynamics of NF-kappaB responses in single living cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

Single-cell NF-kappaB dynamics reveal digital activation and analogue information processing.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

A noisy paracrine signal determines the cellular NF-kappaB response to lipopolysaccharide

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

Molecular mechanisms involved in inflammasome activation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

An oligomeric signaling platform formed by the Toll-like receptor signal transducers MyD88 and IRAK-4.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

Pulsatile stimulation determines timing and specificity of NF-kappaB-dependent transcription

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

A20: central gatekeeper in inflammation and immunity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

TRIF and IRF-3 binding to the TNF promoter results in macrophage TNF dysregulation and steatosis induced by chronic ethanol

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

IkappaB kinase beta phosphorylates the K63 deubiquitinase A20 to cause feedback inhibition of the NF-kappaB pathway

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

Transient IkappaB kinase activity mediates temporal NF-kappaB dynamics in response to a wide range of tumor necrosis factor-alpha doses

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

Achieving stability of lipopolysaccharide-induced NF-kappaB activation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

NF-kappaB and AP-1 connection: mechanism of NF-kappaB-dependent regulation of AP-1 activity.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

TNF-alpha gene expression in macrophages: regulation by NF-kappa B is independent of c-Jun or C/EBP beta

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

PDZK1 is a novel factor in breast cancer that is indirectly regulated by estrogen through IGF-1R and promotes estrogen-mediated growth

3 June 2018

1 reference

https://api.crossref.org/works/10.1038/S41598-017-01600-Y

Toll-like receptor 3 and 4 signalling through the TRIF and TRAM adaptors in haematopoietic cells promotes atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/S41598-017-01600-Y

The molecular basis of the host response to lipopolysaccharide

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5431130

Unresponsiveness of MyD88-deficient mice to endotoxin

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28469251

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12 December 2020

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DOI

10.1038/S41598-017-01600-Y

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9 June 2020

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9 June 2020

28469251

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