Insulin-like peptide 2 Dmel_CG8167 (Q29819596)

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Protein found in Drosophila melanogaster

Ilp2
Insulin-like peptide
Insulin-like peptide 2
drosophila insulin like peptide 2
Insulin- related peptide 2
Insulin-related peptide
CG8167 gene product from transcript CG8167-RA
drosophila insulin-like peptide 2
insulin-like 2
Ilp2-PA
Dilp2
insulin-like peptide-2
drosophila insulin-like receptor
CG8167-PA

Language	Label	Description	Also known as
English	Insulin-like peptide 2 Dmel_CG8167	Protein found in Drosophila melanogaster	Ilp2 Insulin-like peptide Insulin-like peptide 2 drosophila insulin like peptide 2 Insulin- related peptide 2 Insulin-related peptide CG8167 gene product from transcript CG8167-RA drosophila insulin-like peptide 2 insulin-like 2 Ilp2-PA Dilp2 insulin-like peptide-2 drosophila insulin-like receptor CG8167-PA

Statements

1 reference

25 May 2022

UniProt protein ID

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

insulin receptor binding

determination method or standard

3 references

24 April 2018

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VT51&geneProductId=UniProtKB:Q9VT51

determination method or standard

24 April 2018

Total Solid-Phase Synthesis of Biologically Active Drosophila Insulin-Like Peptide 2 (DILP2).

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VT51&geneProductId=UniProtKB:Q9VT51

determination method or standard

24 April 2018

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VT51&geneProductId=UniProtKB:Q9VT51

determination method or standard

hormone activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

protein binding

determination method or standard

1 reference

8 April 2019

Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

growth factor activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

insulin receptor binding

determination method or standard

extracellular region

determination method or standard

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

8 April 2019

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

extracellular space

determination method or standard

3 references

8 April 2019

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

8 April 2019

Dietary sugar promotes systemic TOR activation in Drosophila through AKH-dependent selective secretion of Dilp3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

8 April 2019

Sir2 Acts through Hepatocyte Nuclear Factor 4 to maintain insulin Signaling and Metabolic Homeostasis in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

biological process

cell surface receptor signaling pathway

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

circadian rhythm

determination method or standard

1 reference

8 April 2019

Lowered insulin signalling ameliorates age-related sleep fragmentation in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

positive regulation of cell population proliferation

determination method or standard

1 reference

8 April 2019

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

insulin receptor signaling pathway

determination method or standard

4 references

24 April 2018

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VT51&geneProductId=UniProtKB:Q9VT51

determination method or standard

24 April 2018

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VT51&geneProductId=UniProtKB:Q9VT51

determination method or standard

24 April 2018

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VT51&geneProductId=UniProtKB:Q9VT51

determination method or standard

24 April 2018

Total Solid-Phase Synthesis of Biologically Active Drosophila Insulin-Like Peptide 2 (DILP2).

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VT51&geneProductId=UniProtKB:Q9VT51

determination method or standard

determination of adult lifespan

determination method or standard

1 reference

24 April 2018

Molecular evolution and functional characterization of Drosophila insulin-like peptides

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VT51&geneProductId=UniProtKB:Q9VT51

determination method or standard

regulation of cell size

determination method or standard

1 reference

8 April 2019

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

carbohydrate utilization

determination method or standard

1 reference

8 April 2019

Deletion of Drosophila insulin-like peptides causes growth defects and metabolic abnormalities

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

regulation of signaling receptor activity

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

positive regulation of cell growth

determination method or standard

determination method or standard

1 reference

8 April 2019

Lowered insulin signalling ameliorates age-related sleep fragmentation in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

larval feeding behavior

determination method or standard

1 reference

8 April 2019

Regulation of hunger-driven behaviors by neural ribosomal S6 kinase in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

response to food

determination method or standard

1 reference

8 April 2019

Sir2 Acts through Hepatocyte Nuclear Factor 4 to maintain insulin Signaling and Metabolic Homeostasis in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

regulation of growth

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

regulation of growth rate

determination method or standard

1 reference

8 April 2019

Molecular evolution and functional characterization of Drosophila insulin-like peptides

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

regulation of multicellular organism growth

determination method or standard

positive regulation of multicellular organism growth

determination method or standard

glucose homeostasis

determination method or standard

1 reference

8 April 2019

Drosophila glucome screening identifies Ck1alpha as a regulator of mammalian glucose metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

locomotor rhythm

determination method or standard

1 reference

8 April 2019

Lowered insulin signalling ameliorates age-related sleep fragmentation in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

positive regulation of cell size

determination method or standard

1 reference

8 April 2019

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

regulation of organ growth

determination method or standard

1 reference

8 April 2019

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

positive regulation of organ growth

determination method or standard

1 reference

8 April 2019

Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

regulation of insulin receptor signaling pathway

determination method or standard

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VT51&geneProductId=UniProtKB:Q9VT51

determination method or standard

entry into reproductive diapause

determination method or standard

1 reference

14 January 2019

The Insulin-Like Proteins dILPs-2/5 Determine Diapause Inducibility in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VT51&geneProductId=UniProtKB:Q9VT51

determination method or standard

female mating behavior

determination method or standard

1 reference

8 April 2019

Insulin signalling regulates remating in female Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

germ-line stem-cell niche homeostasis

determination method or standard

1 reference

8 April 2019

Insulin levels control female germline stem cell maintenance via the niche in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

triglyceride homeostasis

determination method or standard

1 reference

8 April 2019

Deletion of Drosophila insulin-like peptides causes growth defects and metabolic abnormalities

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

cellular response to glucose stimulus

determination method or standard

1 reference

8 April 2019

A genetic strategy to measure circulating Drosophila insulin reveals genes regulating insulin production and secretion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

response to amino acid starvation

determination method or standard

1 reference

8 April 2019

Dietary sugar promotes systemic TOR activation in Drosophila through AKH-dependent selective secretion of Dilp3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

negative regulation of feeding behavior

determination method or standard

1 reference

8 April 2019

Minibrain/Dyrk1a regulates food intake through the Sir2-FOXO-sNPF/NPY pathway in Drosophila and mammals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

insulin receptor signaling pathway

determination method or standard

4 references

14 January 2019

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VT51&geneProductId=UniProtKB:Q9VT51

determination method or standard

14 January 2019

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VT51&geneProductId=UniProtKB:Q9VT51

determination method or standard

14 January 2019

Total Solid-Phase Synthesis of Biologically Active Drosophila Insulin-Like Peptide 2 (DILP2).

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VT51&geneProductId=UniProtKB:Q9VT51

determination method or standard

14 January 2019

Drosophila Insulin-Like Peptides DILP2 and DILP5 Differentially Stimulate Cell Signaling and Glycogen Phosphorylase to Regulate Longevity.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VT51&geneProductId=UniProtKB:Q9VT51

determination method or standard

determination of adult lifespan

determination method or standard

negative regulation of glycogen catabolic process

determination method or standard

1 reference

8 April 2019

Drosophila Insulin-Like Peptides DILP2 and DILP5 Differentially Stimulate Cell Signaling and Glycogen Phosphorylase to Regulate Longevity.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

phosphatidylinositol phosphate biosynthetic process

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

insulin receptor signaling pathway

determination method or standard

5 references

8 April 2019

Innate Immune Signaling in Drosophila Blocks Insulin Signaling by Uncoupling PI(3,4,5)P3 Production and Akt Activation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

8 April 2019

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

8 April 2019

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

8 April 2019

Total Solid-Phase Synthesis of Biologically Active Drosophila Insulin-Like Peptide 2 (DILP2).

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

8 April 2019

Drosophila Insulin-Like Peptides DILP2 and DILP5 Differentially Stimulate Cell Signaling and Glycogen Phosphorylase to Regulate Longevity.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

negative regulation of entry into reproductive diapause

determination method or standard

1 reference

8 April 2019

The Insulin-Like Proteins dILPs-2/5 Determine Diapause Inducibility in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VT51

determination method or standard

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

Wikipedia(0 entries)

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Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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