Ribosomal protein S6 kinase Dmel_CG10539 (Q29817385)

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Protein found in Drosophila melanogaster

S6k-PA
S6-kinase
p70S6 kinase
dS6 kinase
ribosomal S6 protein kinase
RPS6-p70-protein kinase
S6kinase
CG10539-PB
protein kinase-like 64F
S6 kinase
CG10539 gene product from transcript CG10539-RB
CG10539-PA
p70 S6 kinase 1
ribosomal protein S6 kinase
p70S6K kinase
p70 S6 kinase
S6k-PB
S6K kinase
S6k
p70 ribosomal S6 kinase

Language	Label	Description	Also known as
English	Ribosomal protein S6 kinase Dmel_CG10539	Protein found in Drosophila melanogaster	S6k-PA S6-kinase p70S6 kinase dS6 kinase ribosomal S6 protein kinase RPS6-p70-protein kinase S6kinase CG10539-PB protein kinase-like 64F S6 kinase CG10539 gene product from transcript CG10539-RB CG10539-PA p70 S6 kinase 1 ribosomal protein S6 kinase p70S6K kinase p70 S6 kinase S6k-PB S6K kinase S6k p70 ribosomal S6 kinase

Statements

1 reference

25 May 2022

UniProt protein ID

Protein kinase-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q94533

ribosomal protein S6 kinase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q94533

Protein kinase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

AGC-kinase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase, ATP binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine/threonine-protein kinase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

nucleotide binding

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

protein kinase activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

protein serine/threonine kinase activity

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

ribosomal protein S6 kinase activity

determination method or standard

3 references

8 April 2019

Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

8 April 2019

A Drosophila gene structurally and functionally homologous to the mammalian 70-kDa s6 kinase gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

protein binding

determination method or standard

1 reference

8 April 2019

TAK1 regulates autophagic cell death by suppressing the phosphorylation of p70 S6 kinase 1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

kinase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

transferase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

determination method or standard

1 reference

8 April 2019

Subcellular localisations of the CPTI collection of YFP-tagged proteins in Drosophila embryos.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

determination method or standard

1 reference

8 April 2019

Subcellular localisations of the CPTI collection of YFP-tagged proteins in Drosophila embryos.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

presynaptic active zone

determination method or standard

1 reference

8 April 2019

S6 kinase localizes to the presynaptic active zone and functions with PDK1 to control synapse development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

biological process

protein phosphorylation

determination method or standard

4 references

8 April 2019

Protein kinases and phosphatases in the Drosophila genome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

8 April 2019

A Drosophila gene structurally and functionally homologous to the mammalian 70-kDa s6 kinase gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

lipid metabolism

determination method or standard

1 reference

8 April 2019

Drosophila insulin pathway mutants affect visual physiology and brain function besides growth, lipid, and carbohydrate metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

response to oxidative stress

determination method or standard

1 reference

8 April 2019

A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

signal transduction

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

myoblast fusion

determination method or standard

1 reference

8 April 2019

Glycolysis supports embryonic muscle growth by promoting myoblast fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

somatic muscle development

determination method or standard

1 reference

8 April 2019

Glycolysis supports embryonic muscle growth by promoting myoblast fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

insulin receptor signaling pathway

determination method or standard

3 references

8 April 2019

Insulin-induced Drosophila S6 kinase activation requires phosphoinositide 3-kinase and protein kinase B.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

8 April 2019

MAPK/ERK signaling regulates insulin sensitivity to control glucose metabolism in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

8 April 2019

Insulin delays the progression of Drosophila cells through G2/M by activating the dTOR/dRaptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

determination of adult lifespan

determination method or standard

1 reference

8 April 2019

Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

regulation of cell size

determination method or standard

1 reference

8 April 2019

A small issue addressed

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

positive regulation of autophagy

determination method or standard

1 reference

8 April 2019

Advantages and limitations of different p62-based assays for estimating autophagic activity in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

positive regulation of macroautophagy

determination method or standard

1 reference

8 April 2019

Role and regulation of starvation-induced autophagy in the Drosophila fat body

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

phosphorylation

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

positive regulation of cell growth

determination method or standard

3 references

8 April 2019

Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

8 April 2019

The genetic control of organ growth: insights from Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

8 April 2019

PAT-related amino acid transporters regulate growth via a novel mechanism that does not require bulk transport of amino acids

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

larval feeding behavior

determination method or standard

1 reference

8 April 2019

Regulation of hunger-driven behaviors by neural ribosomal S6 kinase in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

multicellular organism growth

determination method or standard

1 reference

8 April 2019

Drosophila insulin pathway mutants affect visual physiology and brain function besides growth, lipid, and carbohydrate metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

intracellular signal transduction

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

female germ-line stem cell population maintenance

determination method or standard

1 reference

8 April 2019

Diet regulates membrane extension and survival of niche escort cells for germline homeostasis via insulin signaling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

positive regulation of multicellular organism growth

determination method or standard

1 reference

8 April 2019

The genetic control of organ growth: insights from Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

positive regulation of cell size

determination method or standard

8 references

8 April 2019

Tor signalling in bugs, brain and brawn

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

8 April 2019

How are the sizes of cells, organs, and bodies controlled?

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

8 April 2019

Rheb promotes cell growth as a component of the insulin/TOR signalling network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

8 April 2019

A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

8 April 2019

Drosophila insulin and target of rapamycin (TOR) pathways regulate GSK3 beta activity to control Myc stability and determine Myc expression in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

8 April 2019

PDGF/VEGF signaling controls cell size in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

8 April 2019

Drosophila S6 kinase: a regulator of cell size

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

8 April 2019

A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

positive regulation of growth

determination method or standard

1 reference

8 April 2019

The genetic control of organ growth: insights from Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

vascular endothelial growth factor receptor signaling pathway

determination method or standard

dendrite morphogenesis

determination method or standard

1 reference

8 April 2019

The target of rapamycin complex 2 controls dendritic tiling of Drosophila sensory neurons through the Tricornered kinase signalling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

synaptic assembly at neuromuscular junction

determination method or standard

1 reference

8 April 2019

S6 kinase localizes to the presynaptic active zone and functions with PDK1 to control synapse development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

positive regulation of axon guidance

determination method or standard

1 reference

8 April 2019

Diet and energy-sensing inputs affect TorC1-mediated axon misrouting but not TorC2-directed synapse growth in a Drosophila model of tuberous sclerosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

regulation of terminal button organization

determination method or standard

1 reference

8 April 2019

A genetic screen identifies Tor as an interactor of VAPB in a Drosophila model of amyotrophic lateral sclerosis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

regulation of response to drug

determination method or standard

1 reference

8 April 2019

Chemical genetic discovery of targets and anti-targets for cancer polypharmacology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q94533

determination method or standard

protein kinase, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q94533

protein kinase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q94533

protein kinase, ATP binding site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q94533

AGC-kinase, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q94533

serine/threonine-protein kinase, active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q94533

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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