Lesswright Dmel_CG3018 (Q29813802)

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Protein found in Drosophila melanogaster

CG3018-PD
lwr-PB
hunchback-like
lwr
ubiquitin-conjugating enzyme 9
lwr-PD
lwr-PC
CG3018-PB
CG3018 gene product from transcript CG3018-RC
CG3018-PC
ubiquitin conjugating enzyme 9
semushi
CG3018-PA
lesswright
lwr-PA

Language	Label	Description	Also known as
English	Lesswright Dmel_CG3018	Protein found in Drosophila melanogaster	CG3018-PD lwr-PB hunchback-like lwr ubiquitin-conjugating enzyme 9 lwr-PD lwr-PC CG3018-PB CG3018 gene product from transcript CG3018-RC CG3018-PC ubiquitin conjugating enzyme 9 semushi CG3018-PA lesswright lwr-PA

Statements

1 reference

25 May 2022

UniProt protein ID

SUMO-conjugating enzyme Ubc9

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q7KNM2

Ubiquitin-conjugating enzyme/RWD-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q7KNM2

Ubiquitin-conjugating enzyme E2 family

1 reference

based on heuristic

inferred from protein domain or family

Ubiquitin-conjugating enzyme, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

nucleotide binding

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

protein binding

determination method or standard

3 references

8 April 2019

Isolation of proteins that interact with the signal transduction molecule Dof and identification of a functional domain conserved between Dof and vertebrate BCAP.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

8 April 2019

A protein interaction map of Drosophila melanogaster

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

8 April 2019

A Drosophila protein-interaction map centered on cell-cycle regulators

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

transcription factor binding

determination method or standard

1 reference

1 January 2018

A functional interaction between dorsal and components of the Smt3 conjugation machinery

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNM2&geneProductId=UniProtKB:Q7KNM2

determination method or standard

heat shock protein binding

determination method or standard

1 reference

8 April 2019

Cloning and developmental expression of a nuclear ubiquitin-conjugating enzyme (DmUbc9) that interacts with small heat shock proteins in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

ubiquitin protein ligase binding

determination method or standard

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNM2&geneProductId=UniProtKB:Q7KNM2

determination method or standard

ubiquitin activating enzyme binding

determination method or standard

1 reference

8 April 2019

Identification of septin-interacting proteins and characterization of the Smt3/SUMO-conjugation system in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

identical protein binding

determination method or standard

1 reference

8 April 2019

Cloning and developmental expression of a nuclear ubiquitin-conjugating enzyme (DmUbc9) that interacts with small heat shock proteins in Drosophila melanogaster

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

ubiquitin protein ligase activity

determination method or standard

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNM2&geneProductId=UniProtKB:Q7KNM2

determination method or standard

SUMO ligase activity

determination method or standard

1 reference

10 September 2018

A functional interaction between dorsal and components of the Smt3 conjugation machinery

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNM2&geneProductId=UniProtKB:Q7KNM2

determination method or standard

transferase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

SUMO conjugating enzyme activity

determination method or standard

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNM2&geneProductId=UniProtKB:Q7KNM2

determination method or standard

SUMO transferase activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

SUMO conjugating enzyme activity

determination method or standard

3 references

8 April 2019

A functional interaction between dorsal and components of the Smt3 conjugation machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

8 April 2019

Conjugation of Smt3 to dorsal may potentiate the Drosophila immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

outer kinetochore

determination method or standard

1 reference

8 April 2019

Genetic and proteomic evidence for roles of Drosophila SUMO in cell cycle control, Ras signaling, and early pattern formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

determination method or standard

2 references

21 June 2018

Genetic and proteomic evidence for roles of Drosophila SUMO in cell cycle control, Ras signaling, and early pattern formation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNM2&geneProductId=UniProtKB:Q7KNM2

determination method or standard

21 June 2018

Cloning and developmental expression of a nuclear ubiquitin-conjugating enzyme (DmUbc9) that interacts with small heat shock proteins in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNM2&geneProductId=UniProtKB:Q7KNM2

determination method or standard

determination method or standard

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNM2&geneProductId=UniProtKB:Q7KNM2

determination method or standard

determination method or standard

3 references

8 April 2019

Genetic and proteomic evidence for roles of Drosophila SUMO in cell cycle control, Ras signaling, and early pattern formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

8 April 2019

Cloning and developmental expression of a nuclear ubiquitin-conjugating enzyme (DmUbc9) that interacts with small heat shock proteins in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

biological process

female meiotic nuclear division

determination method or standard

1 reference

8 April 2019

The Drosophila UBC9 homologue lesswright mediates the disjunction of homologues in meiosis I.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

zygotic specification of dorsal/ventral axis

determination method or standard

1 reference

1 January 2018

A functional interaction between dorsal and components of the Smt3 conjugation machinery

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNM2&geneProductId=UniProtKB:Q7KNM2

determination method or standard

determination method or standard

1 reference

8 April 2019

Medea SUMOylation restricts the signaling range of the Dpp morphogen in the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

germ cell migration

determination method or standard

1 reference

8 April 2019

BMP signaling and the maintenance of primordial germ cell identity in Drosophila embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

female meiosis chromosome segregation

determination method or standard

1 reference

8 April 2019

The Drosophila UBC9 homologue lesswright mediates the disjunction of homologues in meiosis I.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

protein sumoylation

determination method or standard

spectrosome organization

determination method or standard

1 reference

8 April 2019

BMP signaling and the maintenance of primordial germ cell identity in Drosophila embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

hemocyte proliferation

determination method or standard

1 reference

1 January 2018

The lesswright mutation activates Rel-related proteins, leading to overproduction of larval hemocytes in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNM2&geneProductId=UniProtKB:Q7KNM2

determination method or standard

negative regulation of lamellocyte differentiation

determination method or standard

1 reference

8 April 2019

dUbc9 negatively regulates the Toll-NF-kappa B pathways in larval hematopoiesis and drosomycin activation in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

negative regulation of hemocyte proliferation

determination method or standard

negative regulation of Toll signaling pathway

determination method or standard

1 reference

1 January 2018

dUbc9 negatively regulates the Toll-NF-kappa B pathways in larval hematopoiesis and drosomycin activation in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNM2&geneProductId=UniProtKB:Q7KNM2

determination method or standard

cellular response to transforming growth factor beta stimulus

determination method or standard

1 reference

8 April 2019

Medea SUMOylation restricts the signaling range of the Dpp morphogen in the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

protein ubiquitination

determination method or standard

1 reference

21 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNM2&geneProductId=UniProtKB:Q7KNM2

determination method or standard

protein sumoylation

determination method or standard

3 references

10 September 2018

Cloning and developmental expression of a nuclear ubiquitin-conjugating enzyme (DmUbc9) that interacts with small heat shock proteins in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNM2&geneProductId=UniProtKB:Q7KNM2

determination method or standard

10 September 2018

Medea SUMOylation restricts the signaling range of the Dpp morphogen in the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNM2&geneProductId=UniProtKB:Q7KNM2

determination method or standard

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KNM2&geneProductId=UniProtKB:Q7KNM2

determination method or standard

positive regulation of antimicrobial peptide production

determination method or standard

1 reference

8 April 2019

Conjugation of Smt3 to dorsal may potentiate the Drosophila immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

protein sumoylation

determination method or standard

4 references

8 April 2019

Cloning and developmental expression of a nuclear ubiquitin-conjugating enzyme (DmUbc9) that interacts with small heat shock proteins in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

8 April 2019

Medea SUMOylation restricts the signaling range of the Dpp morphogen in the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

8 April 2019

Conjugation of Smt3 to dorsal may potentiate the Drosophila immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

negative regulation of hemocyte differentiation

determination method or standard

1 reference

8 April 2019

The Friend of GATA Transcriptional Co-Regulator, U-Shaped, Is a Downstream Antagonist of Dorsal-Driven Prohemocyte Differentiation in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

positive regulation of DNA-binding transcription factor activity

determination method or standard

1 reference

8 April 2019

Conjugation of Smt3 to dorsal may potentiate the Drosophila immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

negative regulation of Toll signaling pathway

determination method or standard

3 references

8 April 2019

dUbc9 negatively regulates the Toll-NF-kappa B pathways in larval hematopoiesis and drosomycin activation in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

8 April 2019

Role for sumoylation in systemic inflammation and immune homeostasis in Drosophila larvae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

8 April 2019

The lesswright mutation activates Rel-related proteins, leading to overproduction of larval hemocytes in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KNM2

determination method or standard

Ubiquitin-conjugating enzyme E2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q7KNM2

Ubiquitin-conjugating enzyme, active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q7KNM2

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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