Inositol 1,4,5-trisphosphate receptor itr-1 CELE_F33D4.2 (Q29798449)

30 September 2019

hierarchical database ID heuristic

part of

RyR/IP3 receptor binding core, RIH domain superfamily

1 reference

Mir domain superfamily

1 reference

inositol 1,4,5-trisphosphate receptors

2 references

Transporter Classification Database ID

1.A.3.2.16

2 October 2019

hierarchical database ID heuristic

Inositol 1,4,5-trisphosphate/ryanodine receptor domain, protein family

1 reference

Ion transport domain, protein family

1 reference

MIR motif domain, protein family

1 reference

RyR/IP3R Homology associated domain, protein family

1 reference

RIH domain, protein family

1 reference

found in taxon

Caenorhabditis elegans

1 reference

5 December 2018

1 reference

5 December 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

1 reference

1 January 2018

calcium channel activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

1 reference

1 January 2018

calcium ion binding

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

protein binding

1 reference

1 January 2018

IRI-1, a LIN-15B homologue, interacts with inositol-1,4,5-triphosphate receptors and regulates gonadogenesis, defecation, and pharyngeal pumping in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

myosin binding

1 reference

1 January 2018

A direct interaction between IP(3) receptors and myosin II regulates IP(3) signaling in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

inositol 1,4,5 trisphosphate binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y0A1&geneProductId=UniProtKB:Q9Y0A1

1 reference

16 July 2018

inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

The inositol trisphosphate receptor regulates a 50-second behavioral rhythm in C. elegans.

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

1 January 2018

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

phosphatidylinositol binding

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

cell component

endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

1 January 2018

1 January 2018

The inositol 1,4,5-trisphosphate receptor regulates epidermal cell migration in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

endoplasmic reticulum membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y0A1&geneProductId=UniProtKB:Q9Y0A1

1 reference

16 July 2018

plasma membrane

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

1 January 2018

1 January 2018

Inositol 1,4,5-trisphosphate receptors are strongly expressed in the nervous system, pharynx, intestine, gonad and excretory cell of Caenorhabditis elegans and are encoded by a single gene (itr-1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

integral component of membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

1 reference

1 January 2018

sarcoplasmic reticulum

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

cytoplasmic vesicle membrane

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

secretory granule membrane

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

biological process

oocyte maturation

1 reference

1 January 2018

Eph and NMDA receptors control Ca2 /calmodulin-dependent protein kinase II activation during C. elegans oocyte meiotic maturation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

calcium ion transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

1 reference

1 January 2018

positive regulation of cytosolic calcium ion concentration

1 reference

1 January 2018

The inositol trisphosphate receptor regulates a 50-second behavioral rhythm in C. elegans.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

1 reference

1 January 2018

rhythmic behavior

1 reference

1 January 2018

The inositol trisphosphate receptor regulates a 50-second behavioral rhythm in C. elegans.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

programmed cell death

1 reference

1 January 2018

Necrotic cell death in C. elegans requires the function of calreticulin and regulators of Ca(2 ) release from the endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

regulation of cell migration

1 reference

1 January 2018

The inositol 1,4,5-trisphosphate receptor regulates epidermal cell migration in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

ejaculation

1 reference

1 January 2018

Inositol 1,4,5-trisphosphate signaling regulates mating behavior in Caenorhabditis elegans males

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

regulation of pharyngeal pumping

Caenorhabditis elegans Galphaq regulates egg-laying behavior via a PLCbeta-independent and serotonin-dependent signaling pathway and likely functions both in the nervous system and in muscle

2 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

1 January 2018

Caenorhabditis elegans Galphaq regulates egg-laying behavior via a PLCbeta-independent and serotonin-dependent signaling pathway and likely functions both in the nervous system and in muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

inositol phosphate-mediated signaling

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

embryonic morphogenesis

1 reference

1 January 2018

Regulated disruption of inositol 1,4,5-trisphosphate signaling in Caenorhabditis elegans reveals new functions in feeding and embryogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

multicellular organismal reproductive process

1 reference

1 January 2018

Calreticulin, a calcium-binding molecular chaperone, is required for stress response and fertility in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

hermaphrodite genitalia morphogenesis

1 reference

1 January 2018

pat-4/ILK and unc-112/Mig-2 are required for gonad function in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

release of sequestered calcium ion into cytosol

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

regulation of filopodium assembly

1 reference

1 January 2018

The inositol 1,4,5-trisphosphate receptor regulates epidermal cell migration in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

transmembrane transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

1 reference

1 January 2018

male mating behavior

1 reference

1 January 2018

Inositol 1,4,5-trisphosphate signaling regulates mating behavior in Caenorhabditis elegans males

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

calcium ion transmembrane transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y0A1

1 reference

1 January 2018

1 reference

Inositol 1,4,5-trisphosphate/ryanodine receptor domain

1 reference

RIH domain

1 reference

RyR/IP3R Homology associated domain

1 reference

Ion transport domain

1 reference

Transporter Classification Database ID

Identifiers

1 reference

14 December 2018

1 reference

14 December 2018

1 reference

14 December 2018

1 reference

14 December 2018

1 reference

14 December 2018

1 reference

14 December 2018

1 reference

5 December 2018

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1.A.3.2.16

2 references

Transporter Classification database

13 March 2020

Transporter Classification database