Protein phosphatase fem-2 CELE_T19C3.8 (Q29796805)

PPM-type phosphatase domain superfamily

1 reference

PPM-type phosphatase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

PPM-type phosphatase, divalent cation binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Caenorhabditis elegans

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

1 reference

1 January 2018

protein binding

6 references

1 January 2018

Caenorhabditis elegans sex-determining protein FEM-2 is a protein phosphatase that promotes male development and interacts directly with FEM-3.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

1 January 2018

Structural Insight into Caenorhabditis elegans Sex-determining Protein FEM-2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

1 January 2018

The Caenorhabditis elegans F-box protein SEL-10 promotes female development and may target FEM-1 and FEM-3 for degradation by the proteasome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

1 January 2018

The Caenorhabditis elegans sex-determining protein FEM-2 and its human homologue, hFEM-2, are Ca2 /calmodulin-dependent protein kinase phosphatases that promote apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

1 January 2018

The Caenorhabditis elegans F-box protein SEL-10 promotes female development and may target FEM-1 and FEM-3 for degradation by the proteasome

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

1 January 2018

A CUL-2 ubiquitin ligase containing three FEM proteins degrades TRA-1 to regulate C. elegans sex determination

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

hydrolase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

1 reference

1 January 2018

calmodulin-dependent protein phosphatase activity

1 reference

1 January 2018

The Caenorhabditis elegans sex-determining protein FEM-2 and its human homologue, hFEM-2, are Ca2 /calmodulin-dependent protein kinase phosphatases that promote apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

cation binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

1 reference

1 January 2018

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

1 reference

1 January 2018

protein serine/threonine phosphatase activity

Structural Insight into Caenorhabditis elegans Sex-determining Protein FEM-2

4 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49863&geneProductId=UniProtKB:P49863

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49863&geneProductId=UniProtKB:P49863

7 November 2018

7 November 2018

Caenorhabditis elegans sex-determining protein FEM-2 is a protein phosphatase that promotes male development and interacts directly with FEM-3.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49863&geneProductId=UniProtKB:P49863

7 November 2018

The Caenorhabditis elegans sex-determining protein FEM-2 and its human homologue, hFEM-2, are Ca2 /calmodulin-dependent protein kinase phosphatases that promote apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49863&geneProductId=UniProtKB:P49863

protein serine/threonine phosphatase activity

Structural Insight into Caenorhabditis elegans Sex-determining Protein FEM-2

5 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

1 January 2018

1 January 2018

Caenorhabditis elegans sex-determining protein FEM-2 is a protein phosphatase that promotes male development and interacts directly with FEM-3.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

1 January 2018

The Caenorhabditis elegans sex-determining protein FEM-2 and its human homologue, hFEM-2, are Ca2 /calmodulin-dependent protein kinase phosphatases that promote apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

protein-containing complex

IBA

cell component

1 reference

1 January 2018

Structural Insight into Caenorhabditis elegans Sex-determining Protein FEM-2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

protein dephosphorylation

biological process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

3 references

1 January 2018

1 January 2018

Caenorhabditis elegans sex-determining protein FEM-2 is a protein phosphatase that promotes male development and interacts directly with FEM-3.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

1 January 2018

The Caenorhabditis elegans sex-determining protein FEM-2 and its human homologue, hFEM-2, are Ca2 /calmodulin-dependent protein kinase phosphatases that promote apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

apoptotic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

1 reference

1 January 2018

male sex determination

1 reference

1 January 2018

Caenorhabditis elegans sex-determining protein FEM-2 is a protein phosphatase that promotes male development and interacts directly with FEM-3.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

masculinization of hermaphroditic germ-line

1 reference

1 January 2018

Caenorhabditis elegans sex-determining protein FEM-2 is a protein phosphatase that promotes male development and interacts directly with FEM-3.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

1 reference

1 January 2018

The Caenorhabditis elegans sex-determining protein FEM-2 and its human homologue, hFEM-2, are Ca2 /calmodulin-dependent protein kinase phosphatases that promote apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

nematode male tail tip morphogenesis

1 reference

1 January 2018

Caenorhabditis elegans sex-determining protein FEM-2 is a protein phosphatase that promotes male development and interacts directly with FEM-3.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

peptidyl-threonine dephosphorylation

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

1 reference

1 January 2018

sex differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

1 reference

1 January 2018

cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49863

1 reference

1 January 2018

PPM-type phosphatase domain

has part(s)

1 reference

PPM-type phosphatase, divalent cation binding

1 reference