Insulin-like receptor subunit beta;Receptor protein-tyrosine kinase;hypothetical protein CELE_Y55D5A.5 (Q29793736)

Protein kinase-like domain superfamily

1 reference

Fibronectin type III superfamily

1 reference

Growth factor receptor cysteine-rich domain superfamily

1 reference

Receptor L-domain superfamily

1 reference

Fibronectin type III, protein family

1 reference

Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family

1 reference

Receptor L-domain, protein family

1 reference

Furin-like cysteine-rich domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Tyrosine-protein kinase, catalytic domain, protein family

1 reference

Tyrosine-protein kinase, active site, protein family

1 reference

found in taxon

Caenorhabditis elegans

1 reference

10 April 2019

1 reference

10 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 reference

1 January 2018

protein kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 reference

1 January 2018

insulin-activated receptor activity

1 reference

21 June 2018

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q968Y9&geneProductId=UniProtKB:Q968Y9

protein binding

1 reference

1 January 2018

Role of synaptic phosphatidylinositol 3-kinase in a behavioral learning response in C. elegans.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

ATP binding

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 January 2018

kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 reference

1 January 2018

transferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 reference

1 January 2018

peptide hormone binding

1 reference

1 January 2018

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

protein kinase binding

1 reference

1 January 2018

Modulation of Caenorhabditis elegans infection sensitivity by the LIN-7 cell junction protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

SH2 domain binding

1 reference

1 January 2018

SHC-1/p52Shc targets the insulin/IGF-1 and JNK signaling pathways to modulate life span and stress response in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 reference

1 January 2018

PTB domain binding

1 reference

1 January 2018

SHC-1/p52Shc targets the insulin/IGF-1 and JNK signaling pathways to modulate life span and stress response in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

receptor tyrosine kinase

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q968Y9&geneProductId=UniProtKB:Q968Y9

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q968Y9&geneProductId=UniProtKB:Q968Y9

10 September 2018

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q968Y9&geneProductId=UniProtKB:Q968Y9

transmembrane signaling receptor activity

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q968Y9&geneProductId=UniProtKB:Q968Y9

insulin receptor substrate binding

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

transmembrane receptor protein tyrosine kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 January 2018

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

cell component

cytoplasm

1 reference

1 January 2018

DAF-2 and ERK couple nutrient availability to meiotic progression during Caenorhabditis elegans oogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

integral component of membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 reference

1 January 2018

axon

1 reference

21 June 2018

Role of synaptic phosphatidylinositol 3-kinase in a behavioral learning response in C. elegans.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q968Y9&geneProductId=UniProtKB:Q968Y9

cytoplasmic vesicle

1 reference

1 January 2018

DAF-2 and ERK couple nutrient availability to meiotic progression during Caenorhabditis elegans oogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

soma

1 reference

1 January 2018

Role of synaptic phosphatidylinositol 3-kinase in a behavioral learning response in C. elegans.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

spanning component of plasma membrane

1 reference

1 January 2018

DAF-2 and ERK couple nutrient availability to meiotic progression during Caenorhabditis elegans oogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

non-motile cilium

1 reference

1 January 2018

IFTA-2 is a conserved cilia protein involved in pathways regulating longevity and dauer formation in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

integral component of plasma membrane

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

insulin receptor complex

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

receptor complex

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

biological process

immune system process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 reference

1 January 2018

carbohydrate metabolic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 reference

1 January 2018

protein phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 reference

1 January 2018

response to oxidative stress

transmembrane receptor protein tyrosine kinase signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q968Y9&geneProductId=UniProtKB:Q968Y9

1 reference

10 September 2018

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 reference

1 January 2018

insulin receptor signaling pathway

1 reference

1 January 2018

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

determination of adult lifespan

Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling

11 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 January 2018

Cell nonautonomy of C. elegans daf-2 function in the regulation of diapause and life span

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 January 2018

Asymmetric arginine dimethylation determines life span in C. elegans by regulating forkhead transcription factor DAF-16.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 January 2018

Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 January 2018

Attenuation of insulin signalling contributes to FSN-1-mediated regulation of synapse development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 January 2018

Mg2 Extrusion from Intestinal Epithelia by CNNM Proteins Is Essential for Gonadogenesis via AMPK-TORC1 Signaling in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 January 2018

eIF4E function in somatic cells modulates ageing in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 January 2018

Manipulation of behavioral decline in Caenorhabditis elegans with the Rag GTPase raga-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 January 2018

Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 January 2018

eIF4E function in somatic cells modulates ageing in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 January 2018

Asymmetric arginine dimethylation determines life span in C. elegans by regulating forkhead transcription factor DAF-16.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

response to UV

heat acclimation

regulation of gene expression

1 reference

1 January 2018

Asymmetric arginine dimethylation determines life span in C. elegans by regulating forkhead transcription factor DAF-16.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

positive regulation of gene expression

1 reference

1 January 2018

Endogenous cGMP regulates adult longevity via the insulin signaling pathway in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

negative regulation of gene expression

regulation of lipid storage

1 reference

1 January 2018

Asymmetric arginine dimethylation determines life span in C. elegans by regulating forkhead transcription factor DAF-16.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

negative regulation of lipid storage

1 reference

1 January 2018

Asymmetric arginine dimethylation determines life span in C. elegans by regulating forkhead transcription factor DAF-16.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 reference

1 January 2018

peptidyl-tyrosine phosphorylation

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

larval feeding behavior

positive regulation of multicellular organism growth

1 reference

1 January 2018

Cyclic GMP-dependent protein kinase EGL-4 controls body size and lifespan in C elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

dauer larval development

6 references

1 January 2018

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 January 2018

Targets of TGF-beta signaling in Caenorhabditis elegans dauer formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 January 2018

Cell nonautonomy of C. elegans daf-2 function in the regulation of diapause and life span

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 January 2018

Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 January 2018

Attenuation of insulin signalling contributes to FSN-1-mediated regulation of synapse development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 January 2018

Functional interaction between beta-catenin and FOXO in oxidative stress signaling

GOA

curator

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

regulation of development, heterochronic

1 reference

1 January 2018

The zinc-finger protein SEA-2 regulates larval developmental timing and adult lifespan in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

dauer exit

1 reference

1 January 2018

Cell nonautonomy of C. elegans daf-2 function in the regulation of diapause and life span

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

innate immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

1 reference

1 January 2018

positive regulation of synaptic assembly at neuromuscular junction

1 reference

1 January 2018

Attenuation of insulin signalling contributes to FSN-1-mediated regulation of synapse development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

protein autophosphorylation

1 reference

1 January 2018

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

positive regulation of neuromuscular synaptic transmission

1 reference

1 January 2018

Attenuation of insulin signalling contributes to FSN-1-mediated regulation of synapse development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

negative regulation of protein localization to nucleus

1 reference

1 January 2018

A Caenorhabditis elegans developmental decision requires insulin signaling-mediated neuron-intestine communication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

regulation of response to reactive oxygen species

1 reference

1 January 2018

Timing requirements for insulin/IGF-1 signaling in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

cellular response to salt

regulation of eating behavior

regulation of dauer entry

negative regulation of dauer entry

regulation of autophagosome assembly

1 reference

1 January 2018

TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

regulation of dauer larval development

1 reference

1 January 2018

Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

1 reference

1 January 2018

Insulin/IGF-1 signaling regulates proteasome activity through the deubiquitinating enzyme UBH-4.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

positive regulation of transcription by RNA polymerase II

1 reference

1 January 2018

Insulin/IGF-1 signaling regulates proteasome activity through the deubiquitinating enzyme UBH-4.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

negative regulation of signal transduction

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q968Y9&geneProductId=UniProtKB:Q968Y9

cell differentiation

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q968Y9&geneProductId=UniProtKB:Q968Y9

glucose homeostasis

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

negative regulation of apoptotic process

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q968Y9&geneProductId=UniProtKB:Q968Y9

positive regulation of ERK1 and ERK2 cascade

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q968Y9&geneProductId=UniProtKB:Q968Y9

positive regulation of phosphatidylinositol 3-kinase signaling

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

positive regulation of MAPK cascade

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

positive regulation of protein kinase B signaling

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q968Y9

tyrosine-protein kinase, active site

has part(s)

1 reference

serine-threonine/tyrosine-protein kinase, catalytic domain

1 reference

Receptor L-domain

1 reference

tyrosine-protein kinase, catalytic domain

1 reference

Furin-like cysteine-rich domain

1 reference

protein kinase domain

1 reference

fibronectin type III

1 reference