T cell exhaustion (Q29620463)

Europe PubMed Central

title

T cell exhaustion (English)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21739672

30 April 2017

1 reference

E. John Wherry

1

1 reference

Europe PubMed Central

PubMed publication ID

21739672

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21739672

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21739672

6 December 2024

language of work or name

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30 April 2017

publication date

June 2011

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21739672

full work available at URL

30 April 2017

http://www.nature.com/articles/ni.2035.pdf

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1038/NI.2035

http://www.nature.com/articles/ni.2035

6 December 2024

1 reference

https://api.crossref.org/works/10.1038/NI.2035

6 December 2024

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21739672

30 April 2017

volume

12

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21739672

30 April 2017

issue

6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21739672

30 April 2017

page(s)

492-9

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21739672

Modulation of dendritic cell function by persistent viruses.

30 April 2017

cites work

1 reference

12 December 2020

Analysis of successful immune responses in persons infected with hepatitis C virus

1 reference

12 December 2020

Regulatory T-cell expansion during chronic viral infection is dependent on endogenous retroviral superantigens

1 reference

12 December 2020

Diversity in T cell memory: an embarrassment of riches

1 reference

12 December 2020

Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection

1 reference

12 December 2020

Programmed death-1-induced interleukin-10 production by monocytes impairs CD4 T cell activation during HIV infection

1 reference

12 December 2020

PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine

1 reference

12 December 2020

Alternative activation of macrophages: an immunologic functional perspective

1 reference

12 December 2020

Essential roles of CD8 CD122 regulatory T cells in the maintenance of T cell homeostasis

1 reference

12 December 2020

B7-1 and B7-2 selectively recruit CTLA-4 and CD28 to the immunological synapse

1 reference

12 December 2020

Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection

1 reference

12 December 2020

Telomerase activity of HIV-1-specific CD8 T cells: constitutive up-regulation in controllers and selective increase by blockade of PD ligand 1 in progressors

1 reference

12 December 2020

Human virus-specific CD8 T cells: diversity specialists.

1 reference

12 December 2020

IDO expression by dendritic cells: tolerance and tryptophan catabolism

1 reference

12 December 2020

Spontaneous resolution of chronic hepatitis C virus infection: are we missing something?

1 reference

12 December 2020

Tissue-specific differences in PD-1 and PD-L1 expression during chronic viral infection: implications for CD8 T-cell exhaustion

1 reference

12 December 2020

NFATc2 and T-bet contribute to T-helper-cell-subset-specific regulation of IL-21 expression

1 reference

12 December 2020

Tumor-infiltrating NY-ESO-1-specific CD8 T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer

1 reference

12 December 2020

Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8 T cells

1 reference

12 December 2020

PD-1 is a regulator of virus-specific CD8 T cell survival in HIV infection

1 reference

12 December 2020

IL-35-mediated induction of a potent regulatory T cell population.

1 reference

12 December 2020

A vital role for interleukin-21 in the control of a chronic viral infection

1 reference

12 December 2020

Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8 T cells

1 reference

12 December 2020

Defective human immunodeficiency virus-specific CD8 T-cell polyfunctionality, proliferation, and cytotoxicity are not restored by antiretroviral therapy.

1 reference

12 December 2020

Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates

1 reference

12 December 2020

HIV-1-specific interleukin-21 CD4 T cell responses contribute to durable viral control through the modulation of HIV-specific CD8 T cell function

1 reference

12 December 2020

Ablation of CD8 and CD4 T cell responses by high viral loads

1 reference

12 December 2020

Hepatitis C Virus (HCV)-Specific CD8 Cells Produce Transforming Growth Factor That Can Suppress HCV-Specific T-Cell Responses

1 reference

12 December 2020

Upregulation of CTLA-4 by HIV-specific CD4 T cells correlates with disease progression and defines a reversible immune dysfunction

1 reference

12 December 2020

Adaptive immune responses in acute and chronic hepatitis C virus infection

1 reference

12 December 2020

HIV nonprogressors preferentially maintain highly functional HIV-specific CD8 T cells

1 reference

12 December 2020

Effector and memory CTL differentiation

1 reference

12 December 2020

IL-7 Engages Multiple Mechanisms to Overcome Chronic Viral Infection and Limit Organ Pathology

1 reference

12 December 2020

Coregulation of CD8 T cell exhaustion by multiple inhibitory receptors during chronic viral infection.

1 reference

12 December 2020

The inhibitory cytokine IL-35 contributes to regulatory T-cell function

1 reference

12 December 2020

Regulation of virus-specific CD4 T cell function by multiple costimulatory receptors during chronic HIV infection

1 reference

12 December 2020

Critical role for perforin-, Fas/FasL-, and TNFR1-mediated cytotoxic pathways in down-regulation of antigen-specific T cells during persistent viral infection

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12 December 2020

IL-10, T cell exhaustion and viral persistence

1 reference

12 December 2020

Viral immune evasion due to persistence of activated T cells without effector function

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12 December 2020

Transcriptional analysis of HIV-specific CD8 T cells shows that PD-1 inhibits T cell function by upregulating BATF

1 reference

12 December 2020

Chronic antigen stimulation alone is sufficient to drive CD8 T cell exhaustion

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12 December 2020

Molecular profiling of cytomegalovirus-induced human CD8 T cell differentiation

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12 December 2020

The AP-1 transcription factor Batf controls T(H)17 differentiation

1 reference

12 December 2020

Intrinsic functional dysregulation of CD4 T cells occurs rapidly following persistent viral infection

1 reference

12 December 2020

Transcriptional repressor Blimp-1 promotes CD8( ) T cell terminal differentiation and represses the acquisition of central memory T cell properties

1 reference

12 December 2020

HIV antigens can induce TGF-beta(1)-producing immunoregulatory CD8 T cells

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12 December 2020

CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms

1 reference

12 December 2020

Identification of a human CD8 regulatory T cell subset that mediates suppression through the chemokine CC chemokine ligand 4.

1 reference

12 December 2020

Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo

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12 December 2020

Redefining chronic viral infection

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12 December 2020

IL-10 blockade facilitates DNA vaccine-induced T cell responses and enhances clearance of persistent virus infection

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12 December 2020

Elimination of chronic viral infection by blocking CD27 signaling.

1 reference

12 December 2020

Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals

1 reference

12 December 2020

Natural regulatory T cells in infectious disease

1 reference

12 December 2020

IL-2, IL-7 and IL-15 as immuno-modulators during SIV/HIV vaccination and treatment

1 reference

12 December 2020

Interleukin-10 determines viral clearance or persistence in vivo

1 reference

12 December 2020

Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

1 reference

12 December 2020

Functional Restoration of HCV-Specific CD8 T Cells by PD-1 Blockade Is Defined by PD-1 Expression and Compartmentalization

1 reference

12 December 2020

Blimp-1 transcription factor is required for the differentiation of effector CD8( ) T cells and memory responses

1 reference

12 December 2020

Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic hepatitis B virus infection

1 reference

12 December 2020

CD3zeta and CD28 down-modulation on CD8 T cells during viral infection.

1 reference

12 December 2020

Characterization of murine BATF: a negative regulator of activator protein-1 activity in the thymus.

1 reference

12 December 2020

Enhancing SIV-specific immunity in vivo by PD-1 blockade

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12 December 2020

Restoring function in exhausted CD8 T cells during chronic viral infection

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12 December 2020

Antigen-independent memory CD8 T cells do not develop during chronic viral infection

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12 December 2020

CD8 T cell dysfunction during chronic viral infection.

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12 December 2020

Regulation and functions of Blimp-1 in T and B lymphocytes

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12 December 2020

NFATc1 regulates PD-1 expression upon T cell activation.

1 reference

12 December 2020

Atypical memory B cells are greatly expanded in individuals living in a malaria-endemic area

1 reference

12 December 2020

Effector CD8 T cell development: a balancing act between memory cell potential and terminal differentiation

1 reference

12 December 2020

HIV-specific IL-21 producing CD4 T cells are induced in acute and chronic progressive HIV infection and are associated with relative viral control

1 reference

12 December 2020

T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes

1 reference

12 December 2020

Integrating genomic signatures for immunologic discovery

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12 December 2020

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

1 reference

12 December 2020

Viral antigen and extensive division maintain virus-specific CD8 T cells during chronic infection

1 reference

12 December 2020

IL-21R on T cells is critical for sustained functionality and control of chronic viral infection

1 reference

12 December 2020

Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment

1 reference

12 December 2020

Are senescence and exhaustion intertwined or unrelated processes that compromise immunity?

1 reference

12 December 2020

Cell-intrinsic transforming growth factor-beta signaling mediates virus-specific CD8 T cell deletion and viral persistence in vivo

1 reference

12 December 2020

Molecular signature of CD8 T cell exhaustion during chronic viral infection.

1 reference

12 December 2020

1 reference

12 December 2020

Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes.

1 reference

12 December 2020

Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells

1 reference

12 December 2020

Continuous recruitment of naive T cells contributes to heterogeneity of antiviral CD8 T cells during persistent infection.

1 reference

12 December 2020

Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8 T cell responses during chronic infection.

1 reference

12 December 2020

SIV-specific CD8 T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection

1 reference

12 December 2020

Transcriptional mechanisms underlying lymphocyte tolerance.

1 reference

12 December 2020

The diversity of costimulatory and inhibitory receptor pathways and the regulation of antiviral T cell responses.

1 reference

12 December 2020

Resolution of a chronic viral infection after interleukin-10 receptor blockade

1 reference

12 December 2020

Hepatitis C Virus (HCV) Sequence Variation Induces an HCV-Specific T-Cell Phenotype Analogous to Spontaneous Resolution

1 reference

12 December 2020

Lytic granule loading of CD8 T cells is required for HIV-infected cell elimination associated with immune control

1 reference

12 December 2020

Infection of dendritic cells by lymphocytic choriomeningitis virus

1 reference

12 December 2020

IL-21 is required to control chronic viral infection

1 reference

12 December 2020

Upregulation of PD-1 expression on HIV-specific CD8 T cells leads to reversible immune dysfunction

1 reference

12 December 2020

An expanding job description for Blimp-1/PRDM1.

1 reference

12 December 2020

Interleukin-21-producing HIV-1-specific CD8 T cells are preferentially seen in elite controllers

1 reference

12 December 2020

Outcome of acute hepatitis C is related to virus-specific CD4 function and maturation of antiviral memory CD8 responses.

1 reference

12 December 2020

Role of thymic output in regulating CD8 T-cell homeostasis during acute and chronic viral infection.

1 reference

12 December 2020

Memory CD8 T-cell differentiation during viral infection

1 reference

12 December 2020

The role of secondary lymphatic tissue in immune deficiency of HIV infection.

1 reference

12 December 2020

Impaired NFAT nuclear translocation results in split exhaustion of virus-specific CD8 T cell functions during chronic viral infection.

1 reference

12 December 2020

Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections

1 reference

12 December 2020

Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection

1 reference

12 December 2020

Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade

1 reference

12 December 2020

Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen–specific CD8 T cell dysfunction in melanoma patients

1 reference

12 December 2020

Comparison of activation versus induction of unresponsiveness of virus-specific CD4 and CD8 T cells upon acute versus persistent viral infection

1 reference

12 December 2020

Repetitive antigen stimulation induces stepwise transcriptome diversification but preserves a core signature of memory CD8( ) T cell differentiation

1 reference

12 December 2020

SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation

1 reference

12 December 2020

A role for the transcriptional repressor Blimp-1 in CD8( ) T cell exhaustion during chronic viral infection.

1 reference

12 December 2020

Lymphocyte activation gene-3 (CD223) regulates the size of the expanding T cell population following antigen activation in vivo

1 reference

12 December 2020

IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection

1 reference

12 December 2020

Functionally distinct LAG-3 and PD-1 subsets on activated and chronically stimulated CD8 T cells

1 reference

12 December 2020

Selective expansion of a subset of exhausted CD8 T cells by alphaPD-L1 blockade

1 reference

12 December 2020

Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection

1 reference

12 December 2020

Immunotherapeutic effects of IL-7 during a chronic viral infection in mice

1 reference

12 December 2020

Synergistic Reversal of Intrahepatic HCV-Specific CD8 T Cell Exhaustion by Combined PD-1/CTLA-4 Blockade

1 reference

12 December 2020

Identifiers

DOI

10.1038/NI.2035

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21739672

PubMed publication ID

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017