Molecular mechanisms of necroptosis: an ordered cellular explosion (Q29616004)

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20823910

30 April 2017

1 reference

necroptotic signaling pathway

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0097527

execution phase of necroptosis

1 reference

Gene Ontology release 2020-05-02

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Gene Ontology release 2020-05-02

2

Galluzzi L

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30 April 2017

4

Kroemer G

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30 April 2017

Vandenabeele P

1

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20823910

30 April 2017

Vanden Berghe T

series ordinal

3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20823910

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20823910

30 April 2017

language of work or name

1 reference

30 April 2017

publication date

October 2010

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20823910

Nature Reviews Molecular Cell Biology

30 April 2017

published in

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20823910

30 April 2017

volume

11

1 reference

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30 April 2017

issue

10

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20823910

30 April 2017

page(s)

700-14

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20823910

Programmed cell death—II. Endocrine potentiation of the breakdown of the intersegmental muscles of silkmoths

30 April 2017

cites work

1 reference

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

31 March 2020

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Developmental apoptosis in C. elegans: a complex CEDnario

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The morphology of various types of cell death in prenatal tissues

31 March 2020

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Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

31 March 2020

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Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

31 March 2020

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TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

31 March 2020

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Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

31 March 2020

1 reference

Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

31 March 2020

1 reference

Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

31 March 2020

1 reference

RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis

31 March 2020

1 reference

Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.

31 March 2020

1 reference

Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway

31 March 2020

1 reference

Regulation of tumor necrosis factor-induced, mitochondria- and reactive oxygen species-dependent cell death by the electron flux through the electron transport chain complex I.

31 March 2020

1 reference

TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death

31 March 2020

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Riboflavin kinase couples TNF receptor 1 to NADPH oxidase

31 March 2020

1 reference

The oxidative metabolism of glutamine. A modulator of reactive oxygen intermediate-mediated cytotoxicity of tumor necrosis factor in L929 fibrosarcoma cells

31 March 2020

1 reference

Alkylating DNA damage stimulates a regulated form of necrotic cell death

31 March 2020

1 reference

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

31 March 2020

1 reference

Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia

31 March 2020

1 reference

Inhibition of ADP/ATP exchange in receptor-interacting protein-mediated necrosis

31 March 2020

1 reference

Lysosomal membrane permeabilization in cell death

31 March 2020

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Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features.

31 March 2020

1 reference

Mitochondrial membrane permeabilization in cell death

31 March 2020

1 reference

Pharmacological manipulation of cell death: clinical applications in sight?

31 March 2020

1 reference

Molecular mechanisms and pathophysiology of necrotic cell death

31 March 2020

1 reference

Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways

31 March 2020

1 reference

A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses

31 March 2020

1 reference

Regulation and function of IKK and IKK-related kinases

31 March 2020

1 reference

Death receptor signal transducers: nodes of coordination in immune signaling networks

31 March 2020

1 reference

NALP inflammasomes: a central role in innate immunity.

31 March 2020

1 reference

Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA.

31 March 2020

1 reference

NF-kappaB protects macrophages from lipopolysaccharide-induced cell death: the role of caspase 8 and receptor-interacting protein

31 March 2020

1 reference

Induction of necrosis in human neutrophils by Shigella flexneri requires type III secretion, IpaB and IpaC invasins, and actin polymerization

31 March 2020

1 reference

Virulent Shigella flexneri causes damage to mitochondria and triggers necrosis in infected human monocyte-derived macrophages

31 March 2020

1 reference

Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC.

31 March 2020

1 reference

The mechanism of cell death during West Nile virus infection is dependent on initial infectious dose

31 March 2020

1 reference

The mode of death of pig kidney cells infected with cowpox virus is governed by the expression of the crmA gene

31 March 2020

1 reference

A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling

31 March 2020

1 reference

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

31 March 2020

1 reference

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

31 March 2020

1 reference

Enhanced cytoprotective effects of the inhibitor of apoptosis protein cellular IAP1 through stabilization with TRAF2.

31 March 2020

1 reference

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

31 March 2020

1 reference

cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

31 March 2020

1 reference

RIPK1 is not essential for TNFR1-induced activation of NF-kappaB.

31 March 2020

1 reference

Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

31 March 2020

1 reference

Necroptosis as an alternative form of programmed cell death

31 March 2020

1 reference

Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes

31 March 2020

1 reference

NF-kappaB suppression by the deubiquitinating enzyme Cezanne: a novel negative feedback loop in pro-inflammatory signaling

31 March 2020

1 reference

Ubiquitin-specific peptidase 21 inhibits tumor necrosis factor alpha-induced nuclear factor kappaB activation via binding to and deubiquitinating receptor-interacting protein 1.

31 March 2020

1 reference

Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain.

31 March 2020

1 reference

TNF-alpha induces two distinct caspase-8 activation pathways

31 March 2020

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Tumor necrosis factor-induced nonapoptotic cell death requires receptor-interacting protein-mediated cellular reactive oxygen species accumulation

31 March 2020

1 reference

Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses

31 March 2020

1 reference

RIP kinases at the crossroads of cell death and survival

31 March 2020

1 reference

Caspase inhibitors promote alternative cell death pathways

31 March 2020

1 reference

Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3.

31 March 2020

1 reference

The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

31 March 2020

1 reference

Identification of RIP1 kinase as a specific cellular target of necrostatins

31 March 2020

1 reference

Structure-activity relationship study of [1,2,3]thiadiazole necroptosis inhibitors

31 March 2020

1 reference

Necrotic cell death and 'necrostatins': now we can control cellular explosion

31 March 2020

1 reference

Virus inhibition of RIP3-dependent necrosis

31 March 2020

1 reference

Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: an update

31 March 2020

1 reference

Protein synthesis persists during necrotic cell death

31 March 2020

1 reference

Caspase activation inhibits proteasome function during apoptosis

31 March 2020

1 reference

Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis

31 March 2020

1 reference

Transcriptional control by PARP-1: chromatin modulation, enhancer-binding, coregulation, and insulation

31 March 2020

1 reference

Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling.

31 March 2020

1 reference

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

31 March 2020

1 reference

Critical role of calpain I in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury.

31 March 2020

1 reference

Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis.

31 March 2020

1 reference

Causal role of apoptosis-inducing factor for neuronal cell death following traumatic brain injury

31 March 2020

1 reference

Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia.

31 March 2020

1 reference

Mitochondrial membrane permeabilization in neuronal injury

31 March 2020

1 reference

AIF-mediated programmed necrosis: a highly regulated way to die.

31 March 2020

1 reference

Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation

31 March 2020

1 reference

Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD depletion and mitochondrial permeability transition

31 March 2020

1 reference

Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator

31 March 2020

1 reference

Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death

31 March 2020

1 reference

The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore

31 March 2020

1 reference

Butylated hydroxyanisole is more than a reactive oxygen species scavenger

31 March 2020

1 reference

The Cellular Fate of Glucose and Its Relevance in Type 2 Diabetes

31 March 2020

1 reference

Tumor necrosis factor-induced modulation of glyoxalase I activities through phosphorylation by PKA results in cell death and is accompanied by the formation of a specific methylglyoxal-derived AGE

31 March 2020

1 reference

Dicarbonyls linked to damage in the powerhouse: glycation of mitochondrial proteins and oxidative stress

31 March 2020

1 reference

Glutamine homeostasis and mitochondrial dynamics

31 March 2020

1 reference

Glutamine: a Trojan horse in ammonia neurotoxicity

31 March 2020

1 reference

TNFalpha and reactive oxygen species in necrotic cell death

31 March 2020

1 reference

Mitochondrial H( ) leak and ROS generation: an odd couple

31 March 2020

1 reference

Mitochondrial generation of free radicals and hypoxic signaling

31 March 2020

1 reference

Reactive oxygen species are involved in FasL-induced caspase-independent cell death and inflammatory responses.

31 March 2020

1 reference

Ceramide mediates caspase-independent programmed cell death

31 March 2020

1 reference

Tumor necrosis factor-alpha-induced reactive oxygen species formation is mediated by JNK1-dependent ferritin degradation and elevation of labile iron pool

31 March 2020

1 reference

Autophagy, ageing and apoptosis: the role of oxidative stress and lysosomal iron

31 March 2020

1 reference

Distinct roles of basal steady-state and induced H-ferritin in tumor necrosis factor-induced death in L929 cells

31 March 2020

1 reference

The intimate relation between nitric oxide and superoxide in apoptosis and cell survival

31 March 2020

1 reference

Reactions of *NO, *NO2 and peroxynitrite in membranes: physiological implications

31 March 2020

1 reference

Peroxynitrite-mediated modification of proteins at physiological carbon dioxide concentration: pH dependence of carbonyl formation, tyrosine nitration, and methionine oxidation

31 March 2020

1 reference

Nitration of the mitochondrial complex I subunit NDUFB8 elicits RIP1- and RIP3-mediated necrosis

31 March 2020

1 reference

Nitrite protects against morbidity and mortality associated with TNF- or LPS-induced shock in a soluble guanylate cyclase-dependent manner

31 March 2020

1 reference

Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer

31 March 2020

1 reference

Identification of 4-hydroxynonenal as a cytotoxic product originating from the peroxidation of liver microsomal lipids

31 March 2020

1 reference

Mitochondrial oxidative stress: implications for cell death

31 March 2020

1 reference

Lysosomes in iron metabolism, ageing and apoptosis

31 March 2020

1 reference

Intralysosomal iron chelation protects against oxidative stress-induced cellular damage.

31 March 2020

1 reference

Phospholipase A2 structure/function, mechanism, and signaling

31 March 2020

1 reference

Tumour-necrosis-factor-mediated cytotoxicity is correlated with phospholipase-A2 activity, but not with arachidonic acid release per se.

31 March 2020

1 reference

Sphingolipid signaling and redox regulation

31 March 2020

1 reference

Ceramide induces non-apoptotic cell death in human glioma cells

31 March 2020

1 reference

Inhibition of tumor necrosis factor-induced cell death in MCF7 by a novel inhibitor of neutral sphingomyelinase

31 March 2020

1 reference

Susceptibility of lysosomes to rupture is a determinant for plasma membrane disruption in tumor necrosis factor alpha-induced cell death

31 March 2020

1 reference

Sustained calpain activation associated with lysosomal rupture executes necrosis of the postischemic CA1 neurons in primates

31 March 2020

1 reference

The role of lysosomal rupture in neuronal death

31 March 2020

1 reference

Inhibition of ischaemic hippocampal neuronal death in primates with cathepsin B inhibitor CA-074: a novel strategy for neuroprotection based on 'calpain-cathepsin hypothesis'.

31 March 2020

1 reference

Cleavage of the plasma membrane Na /Ca2 exchanger in excitotoxicity

31 March 2020

1 reference

Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology.

31 March 2020

1 reference

Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization

31 March 2020

1 reference

Nuclear heat shock protein 72 as a negative regulator of oxidative stress (hydrogen peroxide)-induced HMGB1 cytoplasmic translocation and release

31 March 2020

1 reference

Involvement of heat shock protein-70 in the mechanism of hydrogen peroxide-induced DNA damage: the role of lysosomes and iron

31 March 2020

1 reference

Mitochondria protection from hypoxia/reoxygenation injury with mitochondria heat shock protein 70 overexpression

31 March 2020

1 reference

Decoding cell death signals in inflammation and immunity

31 March 2020

1 reference

Molecular mechanisms of late apoptotic/necrotic cell clearance

31 March 2020

1 reference

Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal.

31 March 2020

1 reference

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

31 March 2020

1 reference

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl

31 March 2020

1 reference

Macrophages use different internalization mechanisms to clear apoptotic and necrotic cells

31 March 2020

1 reference

Phosphatidylserine exposure during early primary necrosis (oncosis) in JB6 cells as evidenced by immunogold labeling technique

31 March 2020

1 reference

Phagocytosis of necrotic cells by macrophages is phosphatidylserine dependent and does not induce inflammatory cytokine production

31 March 2020

1 reference

Rapid, noninflammatory and PS-dependent phagocytic clearance of necrotic cells

31 March 2020

1 reference

Mechanisms of internalization of apoptotic and necrotic L929 cells by a macrophage cell line studied by electron microscopy

31 March 2020

1 reference

Alveolar macrophages from subjects with chronic obstructive pulmonary disease are deficient in their ability to phagocytose apoptotic airway epithelial cells

31 March 2020

1 reference

A deficiency in the in vivo clearance of apoptotic cells is a feature of the NOD mouse

31 March 2020

1 reference

Phagocytosis in atherosclerosis: Molecular mechanisms and implications for plaque progression and stability.

31 March 2020

1 reference

SLE--a disease of clearance deficiency?

31 March 2020

1 reference

Immune response against dying tumor cells

31 March 2020

1 reference

Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death

31 March 2020

1 reference

Extracellular histones are major mediators of death in sepsis

31 March 2020

1 reference

Circulating mitochondrial DAMPs cause inflammatory responses to injury

31 March 2020

1 reference

Role of murine cytomegalovirus US22 gene family members in replication in macrophages

31 March 2020

1 reference

Inhibition of proinflammatory and innate immune signaling pathways by a cytomegalovirus RIP1-interacting protein

31 March 2020

1 reference

Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling

31 March 2020

1 reference

Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice

31 March 2020

1 reference

Physiological cell death of chondrocytes in vivo is not confined to apoptosis. New observations on the mammalian growth plate

31 March 2020

1 reference

The fate of epithelial cells in the human large intestine

31 March 2020

1 reference

Interdigital cell death can occur through a necrotic and caspase-independent pathway.

31 March 2020

1 reference

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

31 March 2020

1 reference

Metals in our minds: therapeutic implications for neurodegenerative disorders

31 March 2020

1 reference

Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation

31 March 2020

1 reference

Disruption of HSP90 function reverts tumor necrosis factor-induced necrosis to apoptosis

31 March 2020

1 reference

Diversity in the mechanisms of neuronal cell death.

31 March 2020

1 reference

The cardioprotective effect of necrostatin requires the cyclophilin-D component of the mitochondrial permeability transition pore

31 March 2020

1 reference

Necrostatin-1 reduces histopathology and improves functional outcome after controlled cortical impact in mice

31 March 2020

1 reference

Protection against hemorrhagic shock in mice genetically deficient in poly(ADP-ribose)polymerase

31 March 2020

1 reference

Inhibition of poly(ADP-ribose) polymerase attenuates the severity of acute pancreatitis and associated lung injury.

31 March 2020

1 reference

Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A2

31 March 2020

1 reference

No death without life: vital functions of apoptotic effectors

31 March 2020

1 reference

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes.

31 March 2020

1 reference

Apoptosis and necrosis: detection, discrimination and phagocytosis

31 March 2020

1 reference

31 March 2020

Signaling to NF-kappaB

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Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

31 March 2020

1 reference

Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

31 March 2020

1 reference

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

31 March 2020

1 reference

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

31 March 2020

1 reference

Nuclear factor-kappaB inhibitors as sensitizers to anticancer drugs

31 March 2020

1 reference

Cancer. Addiction to oncogenes--the Achilles heal of cancer

31 March 2020

1 reference

RIP3, a novel apoptosis-inducing kinase

31 March 2020

1 reference

Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis.

31 March 2020

1 reference

12 December 2020

TNF-induced intracellular signaling leading to gene induction or to cytotoxicity by necrosis or by apoptosis.

1 reference

12 December 2020

RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis

1 reference

12 December 2020

Sphingosine-induced apoptosis is dependent on lysosomal proteases

1 reference

12 December 2020

Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation

1 reference

12 December 2020

Necroptosis, a novel form of caspase-independent cell death, contributes to neuronal damage in a retinal ischemia-reperfusion injury model

1 reference

12 December 2020

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20823910

Identifiers

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1014854268

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Fatcat ID

release_kn3etefjh5evjhsztt5fnn4i3a

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Fatcat

https://api.fatcat.wiki/v0/release/kn3etefjh5evjhsztt5fnn4i3a

24 November 2022

mapped directly with Wikidata item

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Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20823910

PubMed publication ID

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017