Leptin and the regulation of body weight in mammals (Q29615976)

Europe PubMed Central

title

Leptin and the regulation of body weight in mammals (English)

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30 April 2017

author name string

Friedman JM

series ordinal

1

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Halaas JL

series ordinal

2

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30 April 2017

language of work or name

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30 April 2017

publication date

22 October 1998

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30 April 2017

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30 April 2017

volume

395

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30 April 2017

issue

6704

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30 April 2017

page(s)

763-70

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The Body-Mass Index of Twins Who Have Been Reared Apart

30 April 2017

cites work

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Tackling a weighty problem

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Positional cloning of the mouse obese gene and its human homologue

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The stomach is a source of leptin

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Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans

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The molecular basis of the obese mutation in ob2J mice

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Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus

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Weight-reducing effects of the plasma protein encoded by the obese gene

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Human leptin characterization

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Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

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Physiological response to long-term peripheral and central leptin infusion in lean and obese mice

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Effects of the obese gene product on body weight regulation in ob/ob mice

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Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks

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The role of neuropeptide Y in the antiobesity action of the obese gene product

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Adipogenesis and obesity: rounding out the big picture

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Serum immunoreactive-leptin concentrations in normal-weight and obese humans

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Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin

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Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression

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Role of leptin in the neuroendocrine response to fasting

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Early onset of reproductive function in normal female mice treated with leptin

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Leptin accelerates the onset of puberty in normal female mice

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Hyperleptinemia of pregnancy associated with the appearance of a circulating form of the leptin receptor.

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Identification and expression cloning of a leptin receptor, OB-R

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Abnormal splicing of the leptin receptor in diabetic mice

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Absence of soluble leptin receptor in plasma from dbPas/dbPas and other db/db mice

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Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

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Divergent signaling capacities of the long and short isoforms of the leptin receptor

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Defective STAT signaling by the leptin receptor in diabetic mice

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Biological action of leptin as an angiogenic factor

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Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization

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Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues.

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Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice

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Leptin activation in hypothalamus.

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Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels.

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Acute stimulation of glucose metabolism in mice by leptin treatment

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7 January 2021

Leptin enters the brain by a saturable system independent of insulin

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7 January 2021

Leptin receptor immunoreactivity in chemically defined target neurons of the hypothalamus

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7 January 2021

OB-Rb gene transfer to leptin-resistant islets reverses diabetogenic phenotype

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7 January 2021

Leptin receptor (OB-R) signaling. Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization

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7 January 2021

Ligand-independent Dimerization of the Extracellular Domain of the Leptin Receptor and Determination of the Stoichiometry of Leptin Binding

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7 January 2021

Enhancing leptin response by preventing SH2-containing phosphatase 2 interaction with Ob receptor

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Identification of SOCS-3 as a potential mediator of central leptin resistance

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The alphabet of weight control

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7 January 2021

Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y.

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7 January 2021

Role of melanocortinergic neurons in feeding and the agouti obesity syndrome

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7 January 2021

Targeted disruption of the melanocortin-4 receptor results in obesity in mice

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7 January 2021

Satiety effect and sympathetic activation of leptin are mediated by hypothalamic melanocortin system

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7 January 2021

Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein

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7 January 2021

Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice

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7 January 2021

Synergy between leptin and cholecystokinin (CCK) to control daily caloric intake

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7 January 2021

Hypothalamic CART is a new anorectic peptide regulated by leptin

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7 January 2021

Mice lacking bombesin receptor subtype-3 develop metabolic defects and obesity

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7 January 2021

The evaluation of insulin as a metabolic signal influencing behavior via the brain

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7 January 2021

A role for melanin-concentrating hormone in the central regulation of feeding behaviour

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7 January 2021

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

1 reference

7 January 2021

Identification of targets of leptin action in rat hypothalamus

1 reference

7 January 2021

Leptin activates neurons in ventrobasal hypothalamus and brainstem

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7 January 2021

Central corticotropin-releasing factor administration prevents the excessive body weight gain of genetically obese (fa/fa) rats

1 reference

7 January 2021

Leptin affects food intake via CRF-receptor-mediated pathways

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7 January 2021

Effect of adrenalectomy and glucocorticoid replacement on development of obesity

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7 January 2021

A receptor subtype involved in neuropeptide-Y-induced food intake

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7 January 2021

Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors

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7 January 2021

Abnormal regulation of the leptin gene in the pathogenesis of obesity

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7 January 2021

A human leptin mutant induces weight gain in normal mice

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7 January 2021

Disappearance of body fat in normal rats induced by adenovirus-mediated leptin gene therapy

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7 January 2021

Mechanism of glucoregulatory responses to stress and their deficiency in diabetes

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7 January 2021

Receptor-mediated regional sympathetic nerve activation by leptin.

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7 January 2021

Role of leptin in fat regulation

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7 January 2021

Induction by leptin of uncoupling protein-2 and enzymes of fatty acid oxidation

1 reference

7 January 2021

Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action

1 reference

7 January 2021

Diet-induced obese mice develop peripheral, but not central, resistance to leptin

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7 January 2021

Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity

1 reference

7 January 2021

Impaired processing of brain proneurotensin and promelanin-concentrating hormone in obese fat/fat mice

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7 January 2021

Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene

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7 January 2021

Identification and characterization of the mouse obesity gene tubby: a member of a novel gene family

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7 January 2021

A candidate gene for the mouse mutation tubby

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7 January 2021

Cerebrospinal fluid leptin levels: relationship to plasma levels and to adiposity in humans

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7 January 2021

Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance

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7 January 2021

Obese gene expression at in vivo levels by fat pads derived from s.c. implanted 3T3-F442A preadipocytes

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7 January 2021

High-frequency firing helps replenish the readily releasable pool of synaptic vesicles

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7 January 2021

Transient increase in obese gene expression after food intake or insulin administration

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7 January 2021

High leptin concentrations in serum of very obese children are further stimulated by dexamethasone

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7 January 2021

The adipocyte specific transcription factor C/EBPalpha modulates human ob gene expression

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7 January 2021

Thiazolidinediones repress ob gene expression in rodents via activation of peroxisome proliferator-activated receptor gamma

1 reference

7 January 2021

Relatively low plasma leptin concentrations precede weight gain in Pima Indians

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7 January 2021

Serum immunoreactive leptin concentrations in patients with anorexia nervosa before and after partial weight recovery

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7 January 2021

Absence of mutations in the human OB gene in obese/diabetic subjects

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7 January 2021

Congenital leptin deficiency is associated with severe early-onset obesity in humans

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7 January 2021

A leptin missense mutation associated with hypogonadism and morbid obesity.

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7 January 2021

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

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7 January 2021

Indication for linkage of the human OB gene region with extreme obesity

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7 January 2021

Extreme obesity may be linked to markers flanking the human OB gene

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7 January 2021

A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2

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7 January 2021

Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

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7 January 2021

Long-term correction of obesity and diabetes in genetically obese mice by a single intramuscular injection of recombinant adeno-associated virus encoding mouse leptin

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7 January 2021

Effect of degree of weight loss on health benefits

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Body Weight and Mortality among Women

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9796811

Identifiers

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30 April 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1048314480

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Mendeley publication ID

871daa37-bf79-362f-8fe3-6726444f8b7f

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https://www.mendeley.com/catalogue/871daa37-bf79-362f-8fe3-6726444f8b7f/

title

Leptin and the regulation of body... preview & related info | Mendeley (British English)

9 October 2022

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Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9796811

PubMed publication ID

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017