A catabolic block does not sufficiently explain how 2-deoxy-D-glucose inhibits cell growth (Q29396272)

14 April 2017

1 reference

M. Ralser

1

Markus

Ralser

1 reference

13 December 2023

7

H. Lehrach

Hans

Lehrach

2 references

14 April 2017

13 December 2023

M. M. Wamelink

2

Mirjam M

Wamelink

2 references

14 April 2017

13 December 2023

E. A. Struys

3

Eduard A

Struys

2 references

14 April 2017

13 December 2023

C. Joppich

4

Christian

Joppich

2 references

14 April 2017

13 December 2023

S. Krobitsch

5

Sylvia

Krobitsch

2 references

14 April 2017

13 December 2023

C. Jakobs

6

Cornelis

Jakobs

2 references

14 April 2017

13 December 2023

language of work or name

English

0 references

publication date

11 November 2008

1 reference

Proceedings of the National Academy of Sciences of the United States of America

14 April 2017

published in

1 reference

14 April 2017

volume

105

1 reference

14 April 2017

issue

46

1 reference

14 April 2017

page(s)

17807-17811

1 reference

Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress

14 April 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress

14 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

2-Deoxy-D-glucose reduces epilepsy progression by NRSF-CtBP-dependent metabolic regulation of chromatin structure

14 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

Glycolysis inhibition for anticancer treatment

14 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding

14 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

Localization of the primary metabolic block produced by 2-deoxyglucose

14 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

On the Origin of Cancer Cells

14 April 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

14 April 2017

https://api.crossref.org/works/10.1073/PNAS.0803090105

S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

Pho85 phosphorylates the Glc7 protein phosphatase regulator Glc8 in vivo.

14 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

The role of the NAD-dependent glutamate dehydrogenase in restoring growth on glucose of a Saccharomyces cerevisiae phosphoglucose isomerase mutant

14 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

P bodies and the control of mRNA translation and degradation

14 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

Intrinsically lower AKT, mammalian target of rapamycin, and hypoxia-inducible factor activity correlates with increased sensitivity to 2-deoxy-D-glucose under hypoxia in lung cancer cell lines

14 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

2-deoxy-D-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

Molecular basis of cyclin-CDK-CKI regulation by reversible binding of an inositol pyrophosphate

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

Under normoxia, 2-deoxy-D-glucose elicits cell death in select tumor types not by inhibition of glycolysis but by interfering with N-linked glycosylation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

Differential toxic mechanisms of 2-deoxy-D-glucose versus 2-fluorodeoxy-D-glucose in hypoxic and normoxic tumor cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

2-Deoxyglucose: an anticancer and antiviral therapeutic, but not any more a low glucose mimetic

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

Role of trehalose phosphate synthase and trehalose during hypoxia: from flies to mammals

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

Identification of the first fungal NADP-GAPDH from Kluyveromyces lactis.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

The hexokinase 2-dependent glucose signal transduction pathway of Saccharomyces cerevisiae

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

Caloric restriction in primates and relevance to humans

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

Mammalian TOR: a homeostatic ATP sensor

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

REG1 binds to protein phosphatase type 1 and regulates glucose repression in Saccharomyces cerevisiae.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

Effects of null mutations in the hexokinase genes of Saccharomyces cerevisiae on catabolite repression

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

Selective depletion of tumor ATP by 2-deoxyglucose and insulin, detected by 31P magnetic resonance spectroscopy

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

The inhibition of bovine heart hexokinase by 2-deoxy-D-glucose-6-phosphate: characterization by 31P NMR and metabolic implications

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

Selective down-regulation of human papillomavirus transcription by 2-deoxyglucose

3 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.0803090105

Quantification of sugar phosphate intermediates of the pentose phosphate pathway by LC-MS/MS: application to two new inherited defects of metabolism

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.0803090105

Glyceraldehyde-3-phosphate dehydrogenase is a GABAA receptor kinase linking glycolysis to neuronal inhibition.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.0803090105

Substrate specificity of brain hexokinase.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584745

Epithelial cell motility: the effect of 2-deoxyglucose on cell migration, ATP production, and the structure of the cytoplasmic ground substance in lamellipodia of epithelial cells in culture

26 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/19004802

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhibition of cell cycle progression by rapamycin induces T cell clonal anergy even in the presence of costimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19004802

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0803090105

2 references

14 April 2017

ADS bibcode

2008PNAS..10517807R

0 references

1 reference

1 reference

1 reference