The pathogenesis of systemic lupus erythematosus—an update (Q29394347)

systemic lupus erythematosus

14 April 2017

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author name string

Jinyoung Choi

series ordinal

1

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14 April 2017

Sang Taek Kim

series ordinal

2

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14 April 2017

Joe Craft

series ordinal

3

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14 April 2017

publication date

December 2012

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Current Opinion in Immunology

14 April 2017

published in

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14 April 2017

volume

24

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14 April 2017

issue

6

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14 April 2017

page(s)

651-657

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A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus

14 April 2017

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IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus

14 April 2017

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Neutrophils in the pathogenesis and manifestations of SLE

14 April 2017

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Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial

14 April 2017

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Follicular helper T cells: lineage and location

14 April 2017

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Neutrophil extracellular traps kill bacteria

14 April 2017

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Follicular helper CD4 T cells (TFH)

14 April 2017

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Interferon and granulopoiesis signatures in systemic lupus erythematosus blood

14 April 2017

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Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

14 April 2017

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Extrafollicular B cell activation by marginal zone dendritic cells drives T cell-dependent antibody responses

14 April 2017

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The genetics of type I interferon in systemic lupus erythematosus

3 June 2018

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Updates on B-cell immunotherapies for systemic lupus erythematosus and Sjogren's syndrome

3 June 2018

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Treatment of systemic lupus erythematosus: new advances in targeted therapy

3 June 2018

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Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: the Lupus Nephritis Assessment with Rituximab study

3 June 2018

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Interferon alpha as a primary pathogenic factor in human lupus

3 June 2018

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An Acquired Defect in IgG-Dependent Phagocytosis Explains the Impairment in Antibody-Mediated Cellular Depletion in Lupus

3 June 2018

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The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans

3 June 2018

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BAFF and selection of autoreactive B cells

3 June 2018

1 reference

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Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus.

3 June 2018

1 reference

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Abnormalities of T cell signaling in systemic lupus erythematosus

3 June 2018

1 reference

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Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus

3 June 2018

1 reference

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Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus

3 June 2018

1 reference

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Dissecting the Immune Cell Mayhem That Drives Lupus Pathogenesis

3 June 2018

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Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes

3 June 2018

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Interferon‐α induces unabated production of short‐lived plasma cells in pre‐autoimmune lupus‐prone (NZB×NZW)F1 mice but not in BALB/c mice

3 June 2018

1 reference

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Human blood CXCR5( )CD4( ) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion

3 June 2018

1 reference

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Dendritic cells in lupus are not required for activation of T and B cells but promote their expansion, resulting in tissue damage

3 June 2018

1 reference

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Genetic susceptibility to systemic lupus erythematosus in the genomic era

3 June 2018

1 reference

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Recent findings on genetics of systemic autoimmune diseases

3 June 2018

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Anti-CD40L immune complexes potently activate platelets in vitro and cause thrombosis in FCGR2A transgenic mice

3 June 2018

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TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus

3 June 2018

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In vivo regulation of Bcl6 and T follicular helper cell development

3 June 2018

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Basophils and the T helper 2 environment can promote the development of lupus nephritis

3 June 2018

1 reference

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Prolonged effects of short-term anti-CD20 B cell depletion therapy in murine systemic lupus erythematosus

3 June 2018

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T cells as therapeutic targets in SLE.

3 June 2018

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Autoimmune response of IgE antibodies to cellular self-antigens in systemic Lupus Erythematosus

3 June 2018

1 reference

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Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: the randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial

3 June 2018

1 reference

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Effect of long-term belimumab treatment on B cells in systemic lupus erythematosus: extension of a phase II, double-blind, placebo-controlled, dose-ranging study

3 June 2018

1 reference

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Dysregulation of germinal centres in autoimmune disease.

3 June 2018

1 reference

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Autoimmune diseases induced by biological agents: a double-edged sword?

3 June 2018

1 reference

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Follicular helper T cells are required for systemic autoimmunity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508331

A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508331

ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity

3 June 2018

1 reference

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Altered B cell receptor signaling in human systemic lupus erythematosus

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508331

T cell-independent and toll-like receptor-dependent antigen-driven activation of autoreactive B cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508331

Association of plasma B lymphocyte stimulator levels and disease activity in systemic lupus erythematosus

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508331

Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors

3 June 2018

1 reference

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Development of TLR inhibitors for the treatment of autoimmune diseases

3 June 2018

1 reference

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Sites and stages of autoreactive B cell activation and regulation.

3 June 2018

1 reference

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B-cell self-tolerance in humans

3 June 2018

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B lymphocyte stimulator (BLyS) isoforms in systemic lupus erythematosus: disease activity correlates better with blood leukocyte BLyS mRNA levels than with plasma BLyS protein levels

3 June 2018

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Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus.

3 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508331

3 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508331

B cell abnormalities in systemic lupus erythematosus

3 June 2018

1 reference

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Short-lived plasmablasts and long-lived plasma cells contribute to chronic humoral autoimmunity in NZB/W mice

3 June 2018

1 reference

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The role of complement in the development of systemic lupus erythematosus

3 June 2018

1 reference

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Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions.

3 June 2018

1 reference

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The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: molecular mechanisms for gene repression

3 June 2018

1 reference

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Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508331

The natural interferon-alpha producing cells in systemic lupus erythematosus

3 June 2018

1 reference

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From T to B and back again: positive feedback in systemic autoimmune disease

3 June 2018

1 reference

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The central and multiple roles of B cells in lupus pathogenesis

3 June 2018

1 reference

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A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus

3 June 2018

1 reference

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Genetic, structural and functional properties of an IgG DNA-binding monoclonal antibody from a lupus patient with nephritis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508331

The role of B cells in lpr/lpr-induced autoimmunity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508331

Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508331

Interleukin 21 correlates with T cell and B cell subset alterations in systemic lupus erythematosus.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508331

Safety and pharmacodynamics of rontalizumab in patients with systemic lupus erythematosus: results of a phase I, placebo-controlled, double-blind, dose-escalation study.

26 November 2018

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Active immunisation of human interferon α transgenic mice with a human interferon α Kinoid induces antibodies that neutralise interferon α in sera from patients with systemic lupus erythematosus

26 November 2018

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Plasma cells in systemic lupus erythematosus: the long and short of it all.

26 November 2018

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Short term administration of costimulatory blockade and cyclophosphamide induces remission of systemic lupus erythematosus nephritis in NZB/W F1 mice by a mechanism downstream of renal immune complex deposition

26 November 2018

1 reference

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Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus.

26 November 2018

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Safety profile and clinical activity of sifalimumab, a fully human anti-interferon α monoclonal antibody, in systemic lupus erythematosus: a phase I, multicentre, double-blind randomised study

26 November 2018

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12 December 2020

Type I IFN protects against murine lupus

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12 December 2020

Short-lived plasmablasts dominate the early spontaneous rheumatoid factor response: differentiation pathways, hypermutating cell types, and affinity maturation outside the germinal center

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12 December 2020

Extrafollicular activation of lymph node B cells by antigen-bearing dendritic cells

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12 December 2020

FcR-bearing myeloid cells are responsible for triggering murine lupus nephritis

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12 December 2020

Depletion of B cells in murine lupus: efficacy and resistance

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12 December 2020

Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus

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12 December 2020

Predominance of Th1 immune response in diffuse proliferative lupus nephritis

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12 December 2020

Evolution of autoantibody responses via somatic hypermutation outside of germinal centers

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12 December 2020

10.1016/J.COI.2012.10.004

Identifiers

DOI

2 references

14 April 2017

1 reference

1 reference

PubMed publication ID

23131610

1 reference