Investigations on recyclisation and hydrolysis in avibactam mediated serine β-lactamase inhibition (Q28834096)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27072755 AND SRC:MED&resulttype=core&format=json

1 April 2020

title

Investigations on recyclisation and hydrolysis in avibactam mediated serine β-lactamase inhibition (English)

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1 April 2020

0 references

1 reference

2

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1 April 2020

Christopher J. Schofield

series ordinal

4

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1 April 2020

author name string

Hwanho Choi

series ordinal

1

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1 April 2020

Hwangseo Park

series ordinal

3

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1 April 2020

language of work or name

English

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publication date

1 April 2016

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Organic and Biomolecular Chemistry

1 April 2020

published in

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1 April 2020

volume

14

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1 April 2020

issue

17

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1 April 2020

page(s)

4116-4128

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Molecular Mechanism of Avibactam-Mediated β-Lactamase Inhibition

1 April 2020

cites work

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Structural Origins of Oxacillinase Specificity in Class D -Lactamases

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Crystal Structures of Yellowtail Ascites Virus VP4 Protease: TRAPPING AN INTERNAL CLEAVAGE SITE TRANS ACYL-ENZYME COMPLEX IN A NATIVE SER/LYS DYAD ACTIVE SITE

16 March 2017

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Structural Insight into Potent Broad-Spectrum Inhibition with Reversible Recyclization Mechanism: Avibactam in Complex with CTX-M-15 and Pseudomonas aeruginosa AmpC -Lactamases

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16 March 2017

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16 March 2017

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Structural and mechanistic basis of penicillin-binding protein inhibition by lactivicins

16 March 2017

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16 March 2017

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Crystal structure of LexA: a conformational switch for regulation of self-cleavage

16 March 2017

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'pH-jump' crystallographic analyses of gamma-lactam-porcine pancreatic elastase complexes

16 March 2017

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Mechanistic insights into the inhibition of serine proteases by monocyclic lactams

16 March 2017

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Inhibition of elastase by N-sulfonylaryl beta-lactams: anatomy of a stable acyl-enzyme complex

16 March 2017

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Crystal structure of a bacterial signal peptidase in complex with a beta-lactam inhibitor

16 March 2017

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Structure of a specific acyl-enzyme complex formed between beta-casomorphin-7 and porcine pancreatic elastase

16 March 2017

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Molecular structure of the acyl-enzyme intermediate in beta-lactam hydrolysis at 1.7 A resolution

16 March 2017

1 reference

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Systematic optimization of long-range corrected hybrid density functionals

16 March 2017

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The chemistry and biological potential of azetidin-2-ones.

6 April 2017

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20 June 2018

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Comparative study of the efficacy and safety of ceftazidime/avibactam plus metronidazole versus meropenem in the treatment of complicated intra-abdominal infections in hospitalized adults: results of a randomized, double-blind, Phase II trial

20 June 2018

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Efficacy and safety of ceftazidime-avibactam versus imipenem-cilastatin in the treatment of complicated urinary tract infections, including acute pyelonephritis, in hospitalized adults: results of a prospective, investigator-blinded, randomized stud

20 June 2018

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Avibactam is a covalent, reversible, non-β-lactam β-lactamase inhibitor

20 June 2018

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20 June 2018

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Diazabicyclooctanes (DBOs): a potent new class of non-β-lactam β-lactamase inhibitors

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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High resolution crystal structures of the trans-enamine intermediates formed by sulbactam and clavulanic acid and E166A SHV-1 {beta}-lactamase

20 June 2018

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5,5-Fused thiophene gamma-lactams as templates for serine protease inhibition

21 January 2018

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Mechanism of acyl-enzyme complex formation from the Henry-Michaelis complex of class C β-lactamases with β-lactam antibiotics.

21 January 2018

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Geometrical reaction coordinates. II. Nucleophilic addition to a carbonyl group

21 January 2018

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Investigation of the mechanism of the cell wall DD-carboxypeptidase reaction of penicillin-binding protein 5 of Escherichia coli by quantum mechanics/molecular mechanics calculations.

21 January 2018

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Hydrolytic stability versus ring size in lactams: implications for the development of lactam antibiotics and other serine protease inhibitors

21 January 2018

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Comparison of simple potential functions for simulating liquid water

21 January 2018

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Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes

21 January 2018

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General atomic and molecular electronic structure system

21 January 2018

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Note on an Approximation Treatment for Many-Electron Systems

21 January 2018

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Inactivation of TEM-1 by Avibactam (NXL-104): Insights from Quantum Mechanics/Molecular Mechanics Metadynamics Simulations

21 January 2018

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Molecular dynamics with coupling to an external bath

21 January 2018

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An Evaluation of Harmonic Vibrational Frequency Scale Factors

21 January 2018

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Design and synthesis of bridged gamma-lactams as analogues of beta-lactam antibiotics

21 January 2018

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Occurrence of a serine residue in the penicillin-binding site of the exocellular DD-carboxy-peptidase-transpeptidase from Streptomyces R61

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27072755

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1039/C6OB00353B

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27072755 AND SRC:MED&resulttype=core&format=json

1 April 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27072755 AND SRC:MED&resulttype=core&format=json

1 April 2020

PubMed publication ID

27072755

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27072755 AND SRC:MED&resulttype=core&format=json