The Effect of DNA-Dependent Protein Kinase on Adeno-Associated Virus Replication (Q28744087)

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0015073

20 November 2024

author name string

Young-Kook Choi

1

0 references

Kevin Nash

2

0 references

Nicholas Muzyczka

4

0 references

Sihong Song

5

0 references

Barry J. Byrne

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21188139

full work available at URL

20 November 2024

language of work or name

English

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publication date

20 December 2010

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0015073&type=printable

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21188139

https://europepmc.org/articles/PMC3004791

20 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21188139

https://europepmc.org/articles/PMC3004791?pdf=render

20 November 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21188139

http://dx.plos.org/10.1371/journal.pone.0015073

20 November 2024

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0015073

20 November 2024

0 references

5

0 references

issue

12

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page(s)

e15073

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copyright license

Creative Commons Attribution 4.0 International

start time

20 December 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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DNA-dependent protein kinase is a molecular target for the development of noncytotoxic radiation-sensitizing drugs

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Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant glioma cells by inducing autophagy

3 June 2018

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3 June 2018

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The Rep protein of adeno-associated virus type 2 interacts with single-stranded DNA-binding proteins that enhance viral replication

3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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DNA damage-induced apoptosis requires the DNA-dependent protein kinase, and is mediated by the latent population of p53.

3 June 2018

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3 June 2018

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Rep-dependent initiation of adeno-associated virus type 2 DNA replication by a herpes simplex virus type 1 replication complex in a reconstituted system

3 June 2018

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DNA helicase-mediated packaging of adeno-associated virus type 2 genomes into preformed capsids

3 June 2018

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Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

3 June 2018

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Effect of DNA-dependent protein kinase on the molecular fate of the rAAV2 genome in skeletal muscle

3 June 2018

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Ku acts in a unique way at the mammalian telomere to prevent end joining

3 June 2018

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Mechanism of Rep-mediated adeno-associated virus origin nicking

3 June 2018

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Mutational analysis of adeno-associated virus type 2 Rep68 protein endonuclease activity on partially single-stranded substrates

3 June 2018

1 reference

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Rep-mediated nicking of the adeno-associated virus origin requires two biochemical activities, DNA helicase activity and transesterification.

3 June 2018

1 reference

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Adeno-associated virus type 2 protein interactions: formation of pre-encapsidation complexes

3 June 2018

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Factors affecting the terminal resolution site endonuclease, helicase, and ATPase activities of adeno-associated virus type 2 Rep proteins

3 June 2018

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Analysis of the effects of charge cluster mutations in adeno-associated virus Rep68 protein in vitro

3 June 2018

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Biochemical characterization of adeno-associated virus rep68 DNA helicase and ATPase activities

3 June 2018

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Herpes simplex virus type 1 immediate-early protein vmw110 induces the proteasome-dependent degradation of the catalytic subunit of DNA-dependent protein kinase.

3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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Recombinant adeno-associated virus type 2 replication and packaging is entirely supported by a herpes simplex virus type 1 amplicon expressing Rep and Cap

3 June 2018

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Control of adeno-associated virus type 2 cap gene expression: relative influence of helper virus, terminal repeats, and Rep proteins

3 June 2018

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Mutational analysis of the adeno-associated virus type 2 Rep68 protein helicase motifs

3 June 2018

1 reference

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The adeno-associated virus type 2 p40 promoter requires a proximal Sp1 interaction and a p19 CArG-like element to facilitate Rep transactivation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3004791

Adeno-associated virus Rep78 protein and terminal repeats enhance integration of DNA sequences into the cellular genome

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3004791

Mutational analysis of the adeno-associated virus Rep68 protein: identification of critical residues necessary for site-specific endonuclease activity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3004791

The cellular transcription factor SP1 and an unknown cellular protein are required to mediate Rep protein activation of the adeno-associated virus p19 promoter.

3 June 2018

1 reference

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The adeno-associated virus (AAV) Rep protein acts as both a repressor and an activator to regulate AAV transcription during a productive infection

3 June 2018

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3 June 2018

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3 June 2018

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Sequence requirements for binding of Rep68 to the adeno-associated virus terminal repeats

3 June 2018

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The phosphatidylinositol 3-kinase inhibitor wortmannin sensitizes murine fibroblasts and human tumor cells to radiation and blocks induction of p53 following DNA damage

3 June 2018

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3 June 2018

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Adeno-associated virus DNA replication in vitro: activation by a maltose binding protein/Rep 68 fusion protein.

3 June 2018

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Identification of linear DNA sequences that specifically bind the adeno-associated virus Rep protein.

3 June 2018

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3 June 2018

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Genetics of adeno-associated virus: isolation and preliminary characterization of adeno-associated virus type 2 mutants

3 June 2018

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Latent infection of KB cells with adeno-associated virus type 2

3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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Expression from the adeno-associated virus p5 and p19 promoters is negatively regulated in trans by the rep protein

3 June 2018

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Effects of PGE1 on platelet deformability.

3 June 2018

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The AAV origin binding protein Rep68 is an ATP-dependent site-specific endonuclease with DNA helicase activity

3 June 2018

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Sequences required for coordinate induction of adeno-associated virus p19 and p40 promoters by Rep protein

3 June 2018

1 reference

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A subset of herpes simplex virus replication genes provides helper functions for productive adeno-associated virus replication

3 June 2018

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Targeted integration of adeno-associated virus (AAV) into human chromosome 19

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3004791

DNA-dependent protein kinase enhances DNA damage-induced apoptosis in association with Friend gp70.

3 June 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0015073

Identification of a replication-defective herpes simplex virus for recombinant adeno-associated virus type 2 (rAAV2) particle assembly using stable producer cell lines

21 January 2018

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Silencing expression of the catalytic subunit of DNA-dependent protein kinase by small interfering RNA sensitizes human cells for radiation-induced chromosome damage, cell killing, and mutation.

21 January 2018

1 reference

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Binding of Ku protein to DNA. Measurement of affinity for ends and demonstration of binding to nicks.

27 November 2018

1 reference

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The inhibition of prostaglandin E1-induced corneal neovascularization by steroid eye drops

27 November 2018

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12 December 2020

Ku polypeptides synthesized in vitro assemble into complexes which recognize ends of double-stranded DNA

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12 December 2020

Competitive and noncompetitive inhibition of the DNA-dependent protein kinase

1 reference

12 December 2020

Wortmannin is a potent inhibitor of DNA double strand break but not single strand break repair in Chinese hamster ovary cells

1 reference

12 December 2020

In vitro replication of adeno-associated virus DNA

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1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0015073

20 November 2024

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