New therapeutic targets for mood disorders (Q28743068)

1

0 references

Lobna A Ibrahim

4

object named as

Lobna Ibrahim

0 references

Carlos A Zarate Jr

9

object named as

Carlos A Zarate

0 references

author name string

Giacomo Salvadore

2

0 references

Nancy DiazGranados

3

0 references

David Latov

5

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Cristina Wheeler-Castillo

6

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Jacqueline Baumann

7

0 references

Ioline D Henter

The Scientific World Journal

8

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language of work or name

English

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publication date

13 April 2010

3 references

13 March 2019

25 January 2021

27 January 2021

3 references

13 March 2019

25 January 2021

27 January 2021

10

0 references

page(s)

713-26

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copyright license

Creative Commons Attribution 3.0 Unported

3 references

Europe PubMed Central

13 March 2019

Europe PubMed Central

25 January 2021

Europe PubMed Central

on focus list of Wikimedia project

27 January 2021

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

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Bipolar disorder: candidate drug targets

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Oxidative stress in psychiatric disorders: evidence base and therapeutic implications

16 March 2017

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16 March 2017

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Additional evidence for anxiolytic- and antidepressant-like activities of saredutant (SR48968), an antagonist at the neurokinin-2 receptor in various rodent-models

6 April 2017

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Agomelatine adjunctive therapy for acute bipolar depression: preliminary open data

16 March 2017

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Efficacy of a protein kinase C inhibitor (tamoxifen) in the treatment of acute mania: a pilot study

16 March 2017

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Severe depression and antidepressants: focus on a pooled analysis of placebo-controlled studies on agomelatine

16 March 2017

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Metabotropic glutamate receptor ligands as possible anxiolytic and antidepressant drugs

16 March 2017

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The prevalence and correlates of adult ADHD in the United States: results from the National Comorbidity Survey Replication

16 March 2017

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Anxiolytic properties of agomelatine, an antidepressant with melatoninergic and serotonergic properties: role of 5-HT2C receptor blockade

16 March 2017

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Epigenetic programming by maternal behavior

16 March 2017

1 reference

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Adenosine administration produces an antidepressant-like effect in mice: evidence for the involvement of A1 and A2A receptors

16 March 2017

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Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7

16 March 2017

1 reference

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5-HT2A and 5-HT2C receptors and their atypical regulation properties

16 March 2017

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Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

(R,S)-4-phosphonophenylglycine, a potent and selective group III metabotropic glutamate receptor agonist, is anticonvulsive and neuroprotective in vivo

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Distinct mechanism for antidepressant activity by blockade of central substance P receptors

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Tachykinins: receptor to effector

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

A molecular mechanism for the effect of lithium on development

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Antidepressant effects of ketamine in depressed patients

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Increased uric acid levels in drug-naïve subjects with bipolar disorder during a first manic episode

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Antidepressant actions of histone deacetylase inhibitors

9 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Mood stabilization and destabilization during acute and continuation phase treatment for bipolar I disorder with lamotrigine or placebo

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Verapamil augmentation of lithium treatment improves outcome in mania unresponsive to lithium alone: preliminary findings and a discussion of therapeutic mechanisms

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

The role of the tripartite glutamatergic synapse in the pathophysiology and therapeutics of mood disorders

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Tachykinin receptors as therapeutic targets in stress-related disorders.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Early effects of mood stabilizers on the Akt/GSK-3beta signaling pathway and on cell survival and proliferation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Treatment of bipolar disorder: new perspectives

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

A double-blind, randomized, placebo-controlled 4-week study on the efficacy and safety of the purinergic agents allopurinol and dipyridamole adjunctive to lithium in acute bipolar mania

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Oxidative stress markers in bipolar disorder: a meta-analysis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

N-acetyl cysteine for depressive symptoms in bipolar disorder--a double-blind randomized placebo-controlled trial

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Rapid onset of antidepressant action: a new paradigm in the research and treatment of major depressive disorder

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Protein kinase C inhibition in the treatment of mania: a double-blind, placebo-controlled trial of tamoxifen

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Mitochondrially mediated plasticity in the pathophysiology and treatment of bipolar disorder.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Physiology and pathophysiology of purinergic neurotransmission

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Preliminary evidence of riluzole efficacy in antidepressant-treated patients with residual depressive symptoms

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Targeting glycogen synthase kinase-3 in the CNS: implications for the development of new treatments for mood disorders

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Involvement of adenosine in the neurobiology of schizophrenia and its therapeutic implications

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Medication augmentation after the failure of SSRIs for depression.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

A pilot study of hormone modulation as a new treatment for mania in women with bipolar affective disorder

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Placebo-controlled trial of agomelatine in the treatment of major depressive disorder

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Lack of efficacy of the substance p (neurokinin1 receptor) antagonist aprepitant in the treatment of major depressive disorder

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

The antiapoptotic actions of mood stabilizers: molecular mechanisms and therapeutic potentials

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Genetic or epigenetic difference causing discordance between monozygotic twins as a clue to molecular basis of mental disorders

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Glycogen synthase kinase-3: a putative molecular target for lithium mimetic drugs

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Remodeling chromatin and stress resistance in the central nervous system: histone deacetylase inhibitors as novel and broadly effective neuroprotective agents.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Therapeutic potential of positive AMPA modulators and their relationship to AMPA receptor subunits. A review of preclinical data

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Antidepressant-like effects of neurokinin receptor antagonists in the forced swim test in the rat.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Sex-specific association between bipolar affective disorder in women and GPR50, an X-linked orphan G protein-coupled receptor

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Riluzole enhances glutamate uptake in rat astrocyte cultures

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Glycogen synthase kinase-3: a target for novel bipolar disorder treatments.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

An open-label trial of riluzole in patients with treatment-resistant major depression

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Regulation of cellular plasticity cascades in the pathophysiology and treatment of mood disorders: role of the glutamatergic system

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Demonstration of the efficacy and safety of a novel substance P (NK1) receptor antagonist in major depression

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Neuropeptide systems as novel therapeutic targets for depression and anxiety disorders

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Modulators of the glutamatergic system: implications for the development of improved therapeutics in mood disorders

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Lithium and valproic acid: parallels and contrasts in diverse signaling contexts

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Determination of the dose of agomelatine, a melatoninergic agonist and selective 5-HT(2C) antagonist, in the treatment of major depressive disorder: a placebo-controlled dose range study

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Glycogen synthase kinase-3beta, mood stabilizers, and neuroprotection

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Riluzole stimulates nerve growth factor, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor synthesis in cultured mouse astrocytes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Novel AMPA receptor potentiators LY392098 and LY404187: effects on recombinant human AMPA receptors in vitro

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Abnormalities in protein kinase C signaling and the pathophysiology of bipolar disorder

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

The purinergic P2 receptor antagonist pyridoxalphosphate-6-azophenyl-2'4'-disulphonic acid prevents both the acute locomotor effects of amphetamine and the behavioural sensitization caused by repeated amphetamine injections in rats

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: molecular transduction of mood stabilization in the treatment of manic-depressive illness

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Ketamine blocks a conditioned taste aversion (CTA) in neonatal rats

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Acute effects of ketamine in the holeboard, the elevated-plus maze, and the social interaction test in Wistar rats

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Effects of the NMDA receptor antagonist ketamine on flavor memory: conditioned aversion, latent inhibition, and habituation of neophobia

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Dizocilpine antagonizes the effect of chronic imipramine on learned helplessness in rats.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Uric-acid metabolism in manic-depressive illness and during lithium therapy

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Functional antagonists at the NMDA receptor complex exhibit antidepressant actions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Chronic treatment with 1-aminocyclopropanecarboxylic acid desensitizes behavioral responses to compounds acting at the N-methyl-D-aspartate receptor complex

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Serotonin, folic acid, and uric acid metabolism in the diagnosis of neuropsychiatric disorders

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035047

Behavioral effects of saredutant, a tachykinin NK2 receptor antagonist, in experimental models of mood disorders under basal and stress-related conditions.

3 June 2018

1 reference

12 December 2020

Decreased glutamate/glutamine levels may mediate cytidine's efficacy in treating bipolar depression: a longitudinal proton magnetic resonance spectroscopy study

1 reference

12 December 2020

1 reference

12 December 2020

Altered platelet protein kinase C activity in bipolar affective disorder, manic episode

1 reference

12 December 2020

Lithium decreases membrane-associated protein kinase C in hippocampus: selectivity for the alpha isozyme

1 reference

12 December 2020

Successful use of S20098 and melatonin in an animal model of delayed sleep-phase syndrome (DSPS).

1 reference

12 December 2020

Chronic sodium valproate selectively decreases protein kinase C alpha and epsilon in vitro.

1 reference

12 December 2020

Chronic administration of imipramine and lithium changes the phase-angle relationship between the activity and core body temperature circadian rhythms in rats

1 reference

12 December 2020

Entrainment of Rat Circadian Rhythms by the Melatonin Agonist S-20098 Requires Intact Suprachiasmatic Nuclei But Not the Pineal

1 reference

12 December 2020

Platelet protein kinase C alpha levels in drug-free and lithium-treated subjects with bipolar disorder

1 reference

12 December 2020

AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test

1 reference

12 December 2020

An open-label trial of the glutamate-modulating agent riluzole in combination with lithium for the treatment of bipolar depression

1 reference

12 December 2020

A detailed behavioral analysis of the acute motor effects of caffeine in the rat: involvement of adenosine A1 and A2A receptors

1 reference

12 December 2020

Analysis of single nucleotide polymorphisms in genes in the chromosome 12Q24.31 region points to P2RX7 as a susceptibility gene to bipolar affective disorder

1 reference

12 December 2020

Agomelatine, a new antidepressant, induces regional changes in hippocampal neurogenesis

1 reference

12 December 2020

P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder

1 reference

12 December 2020

Allopurinol as an adjunct to lithium and haloperidol for treatment of patients with acute mania: a double-blind, randomized, placebo-controlled trial

1 reference

12 December 2020

Antidepressant-like effects of agomelatine (S 20098) in the learned helplessness model

1 reference

12 December 2020

Serum creatine kinase level in unmedicated nonpsychotic, psychotic, bipolar and schizoaffective depressed patients

1 reference

12 December 2020

The anticonvulsants lamotrigine, riluzole, and valproate differentially regulate AMPA receptor membrane localization: relationship to clinical effects in mood disorders

1 reference

12 December 2020

Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse

1 reference

12 December 2020

Oxidative stress parameters in unmedicated and treated bipolar subjects during initial manic episode: A possible role for lithium antioxidant effects

1 reference

12 December 2020

Protein kinase C inhibition by tamoxifen antagonizes manic-like behavior in rats: implications for the development of novel therapeutics for bipolar disorder.

1 reference

12 December 2020

Creatine monohydrate in resistant depression: a preliminary study

1 reference

12 December 2020

Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus

1 reference

12 December 2020

Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors

1 reference

12 December 2020

Brain creatine kinase activity in an animal model of mania

1 reference

12 December 2020

A preliminary investigation of a protein kinase C inhibitor in the treatment of acute mania

1 reference

12 December 2020

Melatonin add-on in manic patients with treatment resistant insomnia

1 reference

12 December 2020

Selective blockade of neurokinin-2 receptors produces antidepressant-like effects associated with reduced corticotropin-releasing factor function

1 reference

12 December 2020

Therapeutic efficacy of allopurinol in mania associated with hyperuricemia

1 reference

12 December 2020

Antidepressant activity of memory-enhancing drugs in the reduction of submissive behavior model

1 reference

12 December 2020

Lipid peroxidation and antioxidant enzyme levels in patients with schizophrenia and bipolar disorder

1 reference

12 December 2020

Purinergic dysfunction in mania: an integrative model

1 reference

12 December 2020

The long-term natural history of the weekly symptomatic status of bipolar I disorder

1 reference

12 December 2020

Effect of agomelatine in the chronic mild stress model of depression in the rat.

1 reference

12 December 2020

Secondary mania caused by caffeine

1 reference

12 December 2020

Effect of riluzole on MK-801 and amphetamine-induced hyperlocomotion

1 reference

12 December 2020

Antidepressant-like effects of NMDA-receptor antagonist injected into the dorsal hippocampus of rats

1 reference

12 December 2020

Danazol and the rapid-cycling patient

1 reference

12 December 2020

Supersensitivity to melatonin suppression by light in young people at high risk for affective disorder. A preliminary report

1 reference

12 December 2020