PPAR-gamma agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease (Q28742454)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21147840 AND SRC:MED&resulttype=core&format=json

18 January 2020

title

PPAR-gamma agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease (English)

1 reference

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autosomal recessive polycystic kidney

18 January 2020

main subject

0 references

1 reference

6

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18 January 2020

2

Hiroki Kurahashi

1 reference

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18 January 2020

author name string

Daisuke Yoshihara

1

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18 January 2020

Miwa Morita

3

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18 January 2020

Masanori Kugita

4

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18 January 2020

Yoshiyuki Hiki

5

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18 January 2020

Tamio Yamaguchi

7

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18 January 2020

James P Calvet

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21147840 AND SRC:MED&resulttype=core&format=json

18 January 2020

Darren P Wallace

9

1 reference

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18 January 2020

Shizuko Nagao

10

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18 January 2020

language of work or name

English

0 references

publication date

8 December 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21147840 AND SRC:MED&resulttype=core&format=json

American Journal of Physiology - Renal Physiology

18 January 2020

published in

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18 January 2020

volume

300

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18 January 2020

issue

2

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18 January 2020

page(s)

F465-74

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Autosomal dominant polycystic kidney disease: the last 3 years

18 January 2020

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Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1.

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Sirolimus reduces polycystic liver volume in ADPKD patients

3 June 2018

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Cholangiocytes with mesenchymal features contribute to progressive hepatic fibrosis of the polycystic kidney rat

3 June 2018

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Fibrocystin/polyductin, found in the same protein complex with polycystin-2, regulates calcium responses in kidney epithelia.

3 June 2018

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Peroxisome proliferator-activated receptor-gamma and retinoic acid X receptor alpha represses the TGFbeta1 gene via PTEN-mediated p70 ribosomal S6 kinase-1 inhibition: role for Zf9 dephosphorylation

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The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease

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Biliary dysgenesis in the PCK rat, an orthologous model of autosomal recessive polycystic kidney disease

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21 January 2018

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PPAR-gamma agonist attenuates renal interstitial fibrosis and inflammation through reduction of TGF-beta

21 January 2018

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21 January 2018

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Pioglitazone improves the phenotype and molecular defects of a targeted Pkd1 mutant

21 January 2018

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Renal activation of extracellular signal-regulated kinase in rats with autosomal-dominant polycystic kidney disease

21 January 2018

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Calcium channel inhibition accelerates polycystic kidney disease progression in the Cy/ rat.

21 January 2018

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Inhibition of mTOR with sirolimus does not attenuate progression of liver and kidney disease in PCK rats

21 January 2018

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Sirolimus and kidney growth in autosomal dominant polycystic kidney disease

21 January 2018

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https://api.crossref.org/works/10.1152/AJPRENAL.00460.2010

Effect of pioglitazone on the early stage of type 2 diabetic nephropathy in KK/Ta mice

21 January 2018

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Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease

21 January 2018

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Mitotic activation of Akt signalling pathway in Han:SPRD rats with polycystic kidney disease.

21 January 2018

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Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD).

21 January 2018

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Everolimus in patients with autosomal dominant polycystic kidney disease.

21 January 2018

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Effectiveness of vasopressin V2 receptor antagonists OPC-31260 and OPC-41061 on polycystic kidney disease development in the PCK rat.

21 January 2018

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21 January 2018

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Cyclic AMP activates B-Raf and ERK in cyst epithelial cells from autosomal-dominant polycystic kidneys

21 January 2018

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Sirolimus attenuates disease progression in an orthologous mouse model of human autosomal dominant polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPRENAL.00460.2010

Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) agonist inhibits transforming growth factor-beta1 and matrix production in human dermal fibroblasts.

21 January 2018

1 reference

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Increased water intake decreases progression of polycystic kidney disease in the PCK rat

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21147840

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Secretion of cytokines and growth factors into autosomal dominant polycystic kidney disease liver cyst fluid

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21147840

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Polycystic liver disease: new insights into disease pathogenesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21147840

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1152/AJPRENAL.00460.2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21147840 AND SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21147840 AND SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

21147840

1 reference