Structural and functional studies of the modulator NS9283 reveal agonist-like mechanism of action at α4β2 nicotinic acetylcholine receptors (Q28655994)

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English	Structural and functional studies of the modulator NS9283 reveal agonist-like mechanism of action at α4β2 nicotinic acetylcholine receptors	scientific article

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21 March 2020

Structural and functional studies of the modulator NS9283 reveal agonist-like mechanism of action at α4β2 nicotinic acetylcholine receptors (English)

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21 March 2020

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Michael Gajhede

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21 March 2020

Joergen Philip Kiaer Ahring

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21 March 2020

Jette S Kastrup

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21 March 2020

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21 March 2020

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Jeppe A Olsen

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21 March 2020

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30 June 2014

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21 March 2020

Journal of Biological Chemistry

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21 March 2020

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21 March 2020

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21 March 2020

24911-24921

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21 March 2020

Molecular recognition of the neurotransmitter acetylcholine by an acetylcholine binding protein reveals determinants of binding to nicotinic acetylcholine receptors

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17 March 2017

A unified model of the GABA(A) receptor comprising agonist and benzodiazepine binding sites

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17 March 2017

Unravelling the mechanism of action of NS9283, a positive allosteric modulator of (α4)3(β2)2 nicotinic ACh receptors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155659

17 March 2017

Synthesis, pharmacology, and biostructural characterization of novel α4β2 nicotinic acetylcholine receptor agonists

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17 March 2017

Structure, function, and modulation of GABA(A) receptors

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17 March 2017

Crystal Structure of Lymnaea stagnalis AChBP Complexed with the Potent nAChR Antagonist DHβE Suggests a Unique Mode of Antagonism

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17 March 2017

Intersubunit Bridge Formation Governs Agonist Efficacy at Nicotinic Acetylcholine 4 2 Receptors: UNIQUE ROLE OF HALOGEN BONDING REVEALED

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17 March 2017

The positive allosteric modulator morantel binds at noncanonical subunit interfaces of neuronal nicotinic acetylcholine receptors

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17 March 2017

Nicotine binding to brain receptors requires a strong cation-pi interaction

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Atomic interactions of neonicotinoid agonists with AChBP: Molecular recognition of the distinctive electronegative pharmacophore

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Galanthamine and Non-competitive Inhibitor Binding to ACh-binding Protein: Evidence for a Binding Site on Non-α-subunit Interfaces of Heteromeric Neuronal Nicotinic Receptors

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17 March 2017

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

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17 March 2017

Comparative protein modelling by satisfaction of spatial restraints

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17 March 2017

Differential regulation of gamma-aminobutyric acid receptor channels by diazepam and phenobarbital

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17 March 2017

Statistical potential for assessment and prediction of protein structures

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7 April 2017

Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures

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7 April 2017

Two distinct allosteric binding sites at α4β2 nicotinic acetylcholine receptors revealed by NS206 and NS9283 give unique insights to binding activity-associated linkage at Cys-loop receptors.

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3 June 2018

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3 June 2018

Augmentation of cognitive function by NS9283, a stoichiometry-dependent positive allosteric modulator of α2- and α4-containing nicotinic acetylcholine receptors.

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3 June 2018

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3 June 2018

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Allosteric modulators of the α4β2 subtype of neuronal nicotinic acetylcholine receptors

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3 June 2018

Binding, activation and modulation of Cys-loop receptors.

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10.1074/JBC.M114.568097

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21 March 2020

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Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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21 March 2020

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