Rho and Rac take center stage (Q28645748)

3 February 2017

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Europe PubMed Central

title

Rho and Rac take center stage (English)

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3 February 2017

2

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author name string

Keith Burridge

series ordinal

1

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3 February 2017

language of work or name

English

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publication date

23 January 2004

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3 February 2017

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3 February 2017

volume

116

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3 February 2017

issue

2

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3 February 2017

page(s)

167–179

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RhoB, not RhoA, represses the transcription of the transforming growth factor beta type II receptor by a mechanism involving activator protein 1.

3 February 2017

cites work

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Chp, a homologue of the GTPase Cdc42Hs, activates the JNK pathway and is implicated in reorganizing the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Bacterial toxins that modify the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Rho GTPases and their effector proteins

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Interactions of ADF/cofilin, Arp2/3 complex, capping protein and profilin in remodeling of branched actin filament networks

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Yop effectors of Yersinia spp. and actin rearrangements

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Biology of the p21-activated kinases

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

ADP-ribosylation factor 6 regulates actin cytoskeleton remodeling in coordination with Rac1 and RhoA.

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Cell-cell adhesion and signalling

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Protein kinase C induces actin reorganization via a Src- and Rho-dependent pathway

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

GTPase regulation: getting aRnd Rock and Rho inhibition

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Both farnesylated and geranylgeranylated RhoB inhibit malignant transformation and suppress human tumor growth in nude mice

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Structural mimicry of DH domains by Arfaptin suggests a model for the recognition of Rac-GDP by its guanine nucleotide exchange factors

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Cloning and functional characterization of related TC10 isoforms, a subfamily of Rho proteins involved in insulin-stimulated glucose transport

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Genomic analysis of metastasis reveals an essential role for RhoC

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Rac regulates integrin-mediated spreading and increased adhesion of T lymphocytes

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

A role for POR1, a Rac1-interacting protein, in ARF6-mediated cytoskeletal rearrangements

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Integrin signaling to the actin cytoskeleton.

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Cell growth inhibition by farnesyltransferase inhibitors is mediated by gain of geranylgeranylated RhoB.

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Rho GTPases in cell biology

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Exploitation of mammalian host cell functions by bacterial pathogens

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Phospholipase C-gamma, protein kinase C and Ca2 /calmodulin-dependent protein kinase II are involved in platelet-derived growth factor-induced phosphorylation of Tiam1.

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Identification of a novel human Rho protein with unusual properties: GTPase deficiency and in vivo farnesylation

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

RGS-containing RhoGEFs: the missing link between transforming G proteins and Rho?

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Small interfering RNAs as a tool to assign Rho GTPase exchange-factor function in vivo

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Regulation of epidermal growth factor receptor traffic by the small GTPase rhoB

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

RhoG GTPase controls a pathway that independently activates Rac1 and Cdc42Hs

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Cdc42Hs facilitates cytoskeletal reorganization and neurite outgrowth by localizing the 58-kD insulin receptor substrate to filamentous actin

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

RhoE regulates actin cytoskeleton organization and cell migration.

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

DBC2, a candidate for a tumor suppressor gene involved in breast cancer

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Induced expression of Rnd3 is associated with transformation of polarized epithelial cells by the Raf-MEK-extracellular signal-regulated kinase pathway

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Both stimulatory and inhibitory exchange proteins, smg GDS and rho GDI, are active on multiple small GTP-binding proteins

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1.

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Arfaptin 1, a putative cytosolic target protein of ADP-ribosylation factor, is recruited to Golgi membranes

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Regulation of the Association of Adducin with Actin Filaments by Rho-associated Kinase (Rho-kinase) and Myosin Phosphatase

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Rac recruits high-affinity integrin alphavbeta3 to lamellipodia in endothelial cell migration

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

The GTPase-activating protein n-chimaerin cooperates with Rac1 and Cdc42Hs to induce the formation of lamellipodia and filopodia

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Localized Rac activation dynamics visualized in living cells

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

The mouse Formin mDia1 is a potent actin nucleation factor regulated by autoinhibition

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

RhoB alteration is necessary for apoptotic and antineoplastic responses to farnesyltransferase inhibitors

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Role of Actin Polymerization and Adhesion to Extracellular Matrix in Rac- and Rho-induced Cytoskeletal Reorganization

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Role of citron kinase as a target of the small GTPase Rho in cytokinesis

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

RhoA is required for cortical retraction and rigidity during mitotic cell rounding

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Activation of ERM proteins in vivo by Rho involves phosphatidyl-inositol 4-phosphate 5-kinase and not ROCK kinases

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Regulation of Tiam1-Rac signalling.

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Rho GTPase-activating proteins in cell regulation

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Coupling of Ras and Rac Guanosine Triphosphatases Through the Ras Exchanger Sos

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Redox-dependent downregulation of Rho by Rac.

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Rho GTPases control polarity, protrusion, and adhesion during cell movement

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Cadherin engagement inhibits RhoA via p190RhoGAP.

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

The small GTPase RalA targets filamin to induce filopodia

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Structural basis for the signaling specificity of RhoG and Rac1 GTPases

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

RhoE binds to ROCK I and inhibits downstream signaling

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

ROCK and Dia have opposing effects on adherens junctions downstream of Rho

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Inhibition of myosin light chain kinase by p21-activated kinase

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

EPS8 and E3B1 transduce signals from Ras to Rac

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Differential binding of arfaptin 2/POR1 to ADP-ribosylation factors and Rac1

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

The pleckstrin homology domain of phospholipase C-beta2 as an effector site for Rac.

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Structural mimicry in bacterial virulence

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Filamins as integrators of cell mechanics and signalling

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Overexpression of the rhoC gene correlates with progression of ductal adenocarcinoma of the pancreas

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Intercellular Adhesion Molecule (ICAM)-1, But Not ICAM-2, Activates RhoA and Stimulates c-fos and rhoA Transcription in Endothelial Cells

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Rho Family GTPases Bind to Phosphoinositide Kinases

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Paxillin-ARF GAP signaling and the cytoskeleton

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Rac regulates phosphorylation of the myosin-II heavy chain, actinomyosin disassembly and cell spreading

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Growth-regulated expression of rhoG, a new member of the ras homolog gene family

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

A novel strategy for specifically down-regulating individual Rho GTPase activity in tumor cells

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Cooperation between mDia1 and ROCK in Rho-induced actin reorganization

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

RhoG signals in parallel with Rac1 and Cdc42

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Rnd proteins function as RhoA antagonists by activating p190 RhoGAP

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

RhoA and ROCK promote migration by limiting membrane protrusions

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

RhoA is required for monocyte tail retraction during transendothelial migration

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

Phosphorylation of ADF/cofilin abolishes EGF-induced actin nucleation at the leading edge and subsequent lamellipod extension

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(04)50003-0

7 January 2021

10.1016/S0092-8674(04)00003-0

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017