IRAK-4 as the central TIR signaling mediator in innate immunity (Q28611512)

3 February 2017

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Europe PubMed Central

title

IRAK-4 as the central TIR signaling mediator in innate immunity (English)

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3 February 2017

Nobutaka Suzuki

1

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3 February 2017

Shinobu Suzuki

series ordinal

2

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3 February 2017

Wen-Chen Yeh

series ordinal

3

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3 February 2017

publication date

1 October 2002

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3 February 2017

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3 February 2017

volume

23

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3 February 2017

issue

10

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3 February 2017

page(s)

503–506

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The evolution and genetics of innate immunity

3 February 2017

cites work

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Chromosomal localization of TIL, a gene encoding a protein related to the Drosophila transmembrane receptor Toll, to human chromosome 4p14.

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Toll-like receptors: critical proteins linking innate and acquired immunity

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

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The Toll/interleukin-1 receptor domain: a molecular switch for inflammation and host defence

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pelle encodes a protein kinase required to establish dorsoventral polarity in the Drosophila embryo

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Activation of the kinase Pelle by Tube in the dorsoventral signal transduction pathway of Drosophila embryo.

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A conserved signaling pathway: the Drosophila toll-dorsal pathway

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IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

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7 January 2021

MyD88: An Adapter That Recruits IRAK to the IL-1 Receptor Complex

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MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways

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7 January 2021

MyD88, an adapter protein involved in interleukin-1 signaling

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7 January 2021

IRAK: a kinase associated with the interleukin-1 receptor

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7 January 2021

IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family

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7 January 2021

IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase

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7 January 2021

Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice

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7 January 2021

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

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7 January 2021

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

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7 January 2021

Unresponsiveness of MyD88-deficient mice to endotoxin

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7 January 2021

Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes

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7 January 2021

Toll-like receptor signal transduction and the tailoring of innate immunity: a role for Mal?

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TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway

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7 January 2021

Interleukin (IL)-1 receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production

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7 January 2021

Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 responses in IL-1 receptor-associated kinase (IRAK)-deficient mice

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7 January 2021

IL-1 receptor-associated kinase modulates host responsiveness to endotoxin.

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7 January 2021

IRAK-M is a negative regulator of Toll-like receptor signaling

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7 January 2021

Effects of IL-1 receptor-associated kinase (IRAK) expression on IL-1 signaling are independent of its kinase activity

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7 January 2021

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

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7 January 2021

TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway

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7 January 2021

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

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7 January 2021

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

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7 January 2021

Interleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway

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7 January 2021

IRAK-mediated translocation of TRAF6 and TAB2 in the interleukin-1-induced activation of NFkappa B

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7 January 2021

Regulation of IL-1 receptor-associated kinases by lipopolysaccharide

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7 January 2021

A variety of microbial components induce tolerance to lipopolysaccharide by differentially affecting MyD88-dependent and -independent pathways

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7 January 2021

Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression

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7 January 2021

Lipopolysaccharide- and lipoteichoic acid-induced tolerance and cross-tolerance: distinct alterations in IL-1 receptor-associated kinase.

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7 January 2021

TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages.

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7 January 2021

Divergence of apoptosis-inducing and preventing signals in bacteria-faced macrophages through myeloid differentiation factor 88 and IL-1 receptor-associated kinase members

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7 January 2021

10.1016/S1471-4906(02)02298-6

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017