Mouse homologue of HOS (mHOS) is overexpressed in skin tumors and implicated in constitutive activation of NF-kappaB (Q28593482)

31 January 2017

title

Mouse homologue of HOS (mHOS) is overexpressed in skin tumors and implicated in constitutive activation of NF-kappaB (English)

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S-phase kinase-associated protein 1

31 January 2017

main subject

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Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha

GOA release 2020-03-11

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F-box and WD-40 domain protein 11

GOA release 2020-03-11

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GOA release 2020-03-11

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Neehar Bhatia

1

1 reference

31 January 2017

Jason R. Herter

2

1 reference

31 January 2017

Thomas J. Slaga

3

1 reference

31 January 2017

Serge Y. Fuchs

4

1 reference

31 January 2017

Vladimir S. Spiegelman

5

1 reference

31 January 2017

language of work or name

English

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publication date

28 February 2002

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31 January 2017

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31 January 2017

volume

21

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31 January 2017

issue

10

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31 January 2017

page(s)

1501–1509

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Activate NF-kappa B or die?

31 January 2017

cites work

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https://api.crossref.org/works/10.1038/SJ.ONC.1205311

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

Increased expression of p50-NF-kappaB and constitutive activation of NF-kappaB transcription factors during mouse skin carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

SCF and Cullin/Ring H2-based ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

Further analysis of c-Ha-ras mutations in papillomas initiated by several polycyclic aromatic hydrocarbons and papillomas from uninitiated, promoter-treated skin in SENCAR mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

Oncogenic Ha-Ras-induced Signaling Activates NF-κB Transcriptional Activity, Which Is Required for Cellular Transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

NF-kappa B is required for H-ras oncogene induced abnormal cell proliferation and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

Inducible degradation of IkappaBalpha by the proteasome requires interaction with the F-box protein h-betaTrCP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

Requirement of NF-κB Activation to Suppress p53-Independent Apoptosis Induced by Oncogenic Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

Elevated expression and point mutation of the Ha-ras proto-oncogene in mouse skin tumors promoted by benzoyl peroxide and other promoting agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

Structure, regulation and function of NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

Rel/NF-κB transcription factors and the control of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

Induction of beta-transducin repeat-containing protein by JNK signaling and its role in the activation of NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

IκB kinase: Beginning, not the end

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

The SCF(HOS/beta-TRCP)-ROC1 E3 ubiquitin ligase utilizes two distinct domains within CUL1 for substrate targeting and ubiquitin ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

Inhibition of NF-kappa-B cellular function via specific targeting of the I-kappa-B-ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

The inhibitors of apoptosis (IAPs) and their emerging role in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

7 January 2021

Elevated expression of Ha-ras is an early event in two-stage skin carcinogenesis in SENCAR mice

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

7 January 2021

Epidermal papillomas and carcinomas induced in uninitiated mouse skin by tumor promoters alone contain a point mutation in the 61st codon of the Ha-ras oncogene

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

7 January 2021

Increased expression of mutated Ha-ras during premalignant progression in SENCAR mouse skin

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

7 January 2021

Wnt/beta-catenin signaling induces the expression and activity of betaTrCP ubiquitin ligase receptor

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

7 January 2021

Identification of a novel 300-kDa factor termed IkappaB alphaE3-F1 that is required for ubiquitinylation of IkappaB alpha

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

7 January 2021

NF-kappaB inactivation converts a hepatocyte cell line TNF-alpha response from proliferation to apoptosis.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

7 January 2021

Frequency ofBCL-2/JH translocations in peripheral blood of follicular lymphoma patients

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1205311

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205311

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Dimensions Publication ID

31 January 2017

1015851441

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