Mouse tumor model for neurofibromatosis type 1 (Q28591456)

31 January 2017

title

Mouse tumor model for neurofibromatosis type 1 (English)

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Transformation related protein 53

31 January 2017

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GOA release 2020-03-11

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GOA release 2020-03-11

author name string

K. S. Vogel

1

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31 January 2017

L. J. Klesse

2

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31 January 2017

S. Velasco-Miguel

3

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31 January 2017

K. Meyers

4

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31 January 2017

E. J. Rushing

5

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31 January 2017

L. F. Parada

6

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31 January 2017

language of work or name

English

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publication date

10 December 1999

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31 January 2017

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31 January 2017

volume

286

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31 January 2017

issue

5447

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31 January 2017

page(s)

2176–2179

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Mouse models of tumor development in neurofibromatosis type 1

31 January 2017

cites work

1 reference

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Sympathetic neuron survival and proliferation are prolonged by loss of p53 and neurofibromin

17 March 2017

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Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors

17 March 2017

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17 March 2017

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17 March 2017

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Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues

17 March 2017

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Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

17 March 2017

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The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins

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17 March 2017

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

17 March 2017

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7 April 2017

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Schwann cell hyperplasia and tumors in transgenic mice expressing a naturally occurring mutant NF2 protein

7 April 2017

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The murine gene p27Kip1 is haplo-insufficient for tumour suppression

29 September 2017

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29 September 2017

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Increased tumor proliferation and genomic instability without decreased apoptosis in MMTV-ras mice deficient in p53

29 September 2017

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29 September 2017

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Ras-GTP levels are elevated in human NF1 peripheral nerve tumors

29 September 2017

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A genetic linkage map of the mouse: current applications and future prospects

29 September 2017

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29 September 2017

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29 September 2017

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Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis

29 September 2017

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29 September 2017

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29 September 2017

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3 June 2018

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Tumor suppressor gene mutations in mice

3 June 2018

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Participation of p53 cellular tumour antigen in transformation of normal embryonic cells

3 June 2018

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Sequence homology shared by neurofibromatosis type-1 gene and IRA-1 and IRA-2 negative regulators of the RAS cyclic AMP pathway.

3 June 2018

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3 June 2018

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27 November 2018

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27 November 2018

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27 November 2018

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Somatic deletion of the neurofibromatosis type 1 gene in a neurofibrosarcoma supports a tumour suppressor gene hypothesis

27 November 2018

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12 December 2020

Tumor suppressor genes

1 reference

12 December 2020

Prognostic factors of colorectal cancer: K-ras mutation, overexpression of the p53 protein, and cell proliferative activity

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12 December 2020

Leiomyosarcoma of the small intestine associated with von Recklinghausen's disease: report of a case

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12 December 2020

p53 expression in neurofibroma and malignant peripheral nerve sheath tumor. An immunohistochemical study of sporadic and NF1-associated tumors

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12 December 2020

Involvement of the Ink4a gene (p16 and p19arf) in murine tumorigenesis

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12 December 2020

10.1126/SCIENCE.286.5447.2176

Identifiers

DOI

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