Functional regulation of the epithelial Na channel by IkappaB kinase-beta occurs via phosphorylation of the ubiquitin ligase Nedd4-2 (Q28589043)

31 January 2017

title

Functional regulation of the epithelial Na channel by IkappaB kinase-beta occurs via phosphorylation of the ubiquitin ligase Nedd4-2 (English)

1 reference

Inhibitor of kappaB kinase beta

31 January 2017

0 references

1 reference

Neural precursor cell expressed, developmentally down-regulated gene 4-like

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Robert S. Edinger

1

1 reference

31 January 2017

Jonathan Lebowitz

2

1 reference

31 January 2017

Hui Li

3

1 reference

31 January 2017

Rodrigo Alzamora

4

1 reference

31 January 2017

Huamin Wang

5

1 reference

31 January 2017

John P. Johnson

6

1 reference

31 January 2017

Kenneth R. Hallows

7

1 reference

31 January 2017

language of work or name

English

0 references

publication date

2 January 2009

1 reference

Journal of Biological Chemistry

31 January 2017

published in

1 reference

31 January 2017

volume

284

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31 January 2017

issue

1

1 reference

31 January 2017

page(s)

150–157

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GRK2 interacts with and phosphorylates Nedd4 and Nedd4-2

31 January 2017

cites work

1 reference

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The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family

17 March 2017

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Regulation and function of IKK and IKK-related kinases

17 March 2017

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Increased airway epithelial Na absorption produces cystic fibrosis-like lung disease in mice

17 March 2017

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betaTrCP-mediated proteolysis of NF-kappaB1 p105 requires phosphorylation of p105 serines 927 and 932.

17 March 2017

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Interactions of beta and gamma ENaC with Nedd4 can be facilitated by an ERK-mediated phosphorylation

17 March 2017

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Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na( ) channel cell surface expression

17 March 2017

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IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

17 March 2017

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The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

17 March 2017

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17 March 2017

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AMP-activated kinase inhibits the epithelial Na channel through functional regulation of the ubiquitin ligase Nedd4-2.

29 September 2017

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Minireview: regulation of epithelial Na channel trafficking

29 September 2017

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Serum- and glucocorticoid-regulated kinase 1 regulates ubiquitin ligase neural precursor cell-expressed, developmentally down-regulated protein 4-2 by inducing interaction with 14-3-3.

29 September 2017

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Cytokines and sodium induce protein kinase A-dependent cell-surface Na,K-ATPase recruitment via dissociation of NF-kappaB/IkappaB/protein kinase A catalytic subunit complex in collecting duct principal cells.

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29 September 2017

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14-3-3 proteins modulate the expression of epithelial Na channels by phosphorylation-dependent interaction with Nedd4-2 ubiquitin ligase.

29 September 2017

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Serum and glucocorticoid inducible kinases functionally regulate ClC-2 channels

29 September 2017

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cAMP and serum and glucocorticoid-inducible kinase (SGK) regulate the epithelial Na( ) channel through convergent phosphorylation of Nedd4-2.

29 September 2017

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Ikappab kinase-beta (ikkbeta) modulation of epithelial sodium channel activity

29 September 2017

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The kinase Grk2 regulates Nedd4/Nedd4-2-dependent control of epithelial Na channels

29 September 2017

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29 September 2017

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29 September 2017

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Differential phosphorylation of the signal-responsive domain of I kappa B alpha and I kappa B beta by I kappa B kinases

29 September 2017

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Targeted degradation of ENaC in response to PKC activation of the ERK1/2 cascade

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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21 January 2018

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21 January 2018

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21 January 2018

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27 November 2018

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27 November 2018

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14-3-3 isoforms are induced by aldosterone and participate in its regulation of epithelial sodium channels

27 November 2018

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