PI 3-kinase p110beta: a new target for antithrombotic therapy (Q28588127)

31 January 2017

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10 January 2020

title

PI 3-kinase p110beta: a new target for antithrombotic therapy (English)

2 references

31 January 2017

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Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

10 January 2020

main subject

1 reference

GOA release 2020-03-11

author

Shaun P Jackson

1

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10 January 2020

Simone M Schoenwaelder

2

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10 January 2020

Warwick Nesbitt

4

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10 January 2020

Christine E Wright

6

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10 January 2020

Philip E. Thompson

13

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10 January 2020

Belinda Abbott

18

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10 January 2020

Sai Lu

21

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10 January 2020

James Angus

24

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10 January 2020

author name string

Isaac Goncalves

3

2 references

31 January 2017

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10 January 2020

Vijaya Kenche

7

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10 January 2020

Hishani Prabaharan

12

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10 January 2020

Nathalie Daniele

16

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Suhasini Kulkarni

17

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10 January 2020

Dilek Saylik

19

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10 January 2020

Catherine Jones

20

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10 January 2020

Simon Giuliano

22

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31 January 2017

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10 January 2020

Cindy L Yap

5

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10 January 2020

Karen E Anderson

8

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10 January 2020

Sacha M Dopheide

9

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10 January 2020

Yuping Yuan

10

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10 January 2020

Sharelle A Sturgeon

11

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Gregg D Smith

14

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10 January 2020

Peter R Shepherd

15

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Sascha C Hughan

23

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Alan D Robertson

25

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10 January 2020

Hatem H Salem

26

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10 January 2020

language of work or name

English

0 references

publication date

17 April 2005

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10 January 2020

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31 January 2017

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10 January 2020

volume

11

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10 January 2020

issue

5

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10 January 2020

page(s)

507-514

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Signaling by distinct classes of phosphoinositide 3-kinases

10 January 2020

cites work

1 reference

p110δ, a novel phosphoinositide 3-kinase in leukocytes

21 April 2017

1 reference

Integrin alpha IIb beta 3-dependent calcium signals regulate platelet-fibrinogen interactions under flow. Involvement of phospholipase C gamma 2

21 April 2017

1 reference

Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine

21 April 2017

1 reference

Fibrinogen-independent platelet adhesion and thrombus formation on subendothelium mediated by glycoprotein IIb-IIIa complex at high shear rate

21 April 2017

1 reference

7 January 2021

Increased platelet deposition on atherosclerotic coronary arteries

1 reference

7 January 2021

Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque

1 reference

7 January 2021

Tissue factor modulates the thrombogenicity of human atherosclerotic plaques.

1 reference

7 January 2021

Distinct mechanisms of platelet aggregation as a consequence of different shearing flow conditions

1 reference

7 January 2021

Expression of tissue factor in high-grade carotid artery stenosis: association with plaque destabilization

1 reference

7 January 2021

Platelets in atherothrombosis

1 reference

7 January 2021

Antiplatelet therapy: in search of the 'magic bullet'.

1 reference

7 January 2021

Essential role for phosphoinositide 3-kinase in shear-dependent signaling between platelet glycoprotein Ib/V/IX and integrin alpha(IIb)beta(3).

1 reference

7 January 2021

Purinergic P2Y12 receptor blockade inhibits shear-induced platelet phosphatidylinositol 3-kinase activation

1 reference

7 January 2021

Phosphoinositide 3-kinases: A conserved family of signal transducers

1 reference

7 January 2021

Class I phosphoinositide 3-kinases.

1 reference

7 January 2021

Phosphoinositide 3-kinases and the regulation of platelet function

1 reference

7 January 2021

Human platelets contain p110delta phosphoinositide 3-kinase

1 reference

7 January 2021

Functional phenotype of phosphoinositide 3-kinase p85alpha-null platelets characterized by an impaired response to GP VI stimulation

1 reference

7 January 2021

Distinct glycoprotein Ib/V/IX and integrin alpha IIbbeta 3-dependent calcium signals cooperatively regulate platelet adhesion under flow.

1 reference

7 January 2021

Signaling through GP Ib-IX-V activates alpha IIb beta 3 independently of other receptors.

1 reference

7 January 2021

The P2Y(12) receptor induces platelet aggregation through weak activation of the alpha(IIb)beta(3) integrin--a phosphoinositide 3-kinase-dependent mechanism

1 reference

7 January 2021

SHIP1 and Lyn Kinase Negatively Regulate Integrin alpha IIb beta 3 signaling in platelets.

1 reference

7 January 2021

Importance of temporal flow gradients and integrin alphaIIbbeta3 mechanotransduction for shear activation of platelets

1 reference

7 January 2021

Relationships between Rap1b, affinity modulation of integrin alpha IIbbeta 3, and the actin cytoskeleton

1 reference

7 January 2021

Intravenous nitroglycerin infusion inhibits cyclic blood flow responses caused by periodic platelet thrombus formation in stenosed canine coronary arteries

1 reference

7 January 2021

In vivo models of arterial thrombosis and thrombolysis.

1 reference

7 January 2021

Functional significance of adenosine 5'-diphosphate receptor (P2Y(12)) in platelet activation initiated by binding of von Willebrand factor to platelet GP Ibalpha induced by conditions of high shear rate

1 reference

7 January 2021

The role of Rap1 in integrin-mediated cell adhesion

1 reference

7 January 2021

Structural insight into substrate specificity and regulatory mechanisms of phosphoinositide 3-kinases

1 reference

7 January 2021

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

1 reference

7 January 2021

PI3-kinase inhibition: a target for drug development?

1 reference

7 January 2021

Synergistic adhesive interactions and signaling mechanisms operating between platelet glycoprotein Ib/IX and integrin alpha IIbbeta 3. Studies in human platelets ans transfected Chinese hamster ovary cells

1 reference

7 January 2021

A selective role for phosphatidylinositol 3,4,5-trisphosphate in the Gi-dependent activation of platelet Rap1B.

1 reference

7 January 2021

Activation of Rap1B by G(i) family members in platelets

1 reference

7 January 2021

Direct effects of caffeine and theophylline on p110 delta and other phosphoinositide 3-kinases. Differential effects on lipid kinase and protein kinase activities

1 reference

7 January 2021

Aprotinin reduces clopidogrel-induced prolongation of the bleeding time in the rat

1 reference

7 January 2021

Identifiers

DOI

10.1038/NM1232

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15834429 AND SRC:MED&resulttype=core&format=json

10 January 2020

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017