The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient (Q28587676)

31 January 2017

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8 January 2020

title

The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient (English)

2 references

31 January 2017

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8 January 2020

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GOA release 2020-03-11

author

Mansoor Husain

16

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8 January 2020

Charles Antzelevitch

17

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8 January 2020

Charles Antzelevitch

18

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8 January 2020

Benoit G. Bruneau

23

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8 January 2020

author name string

Pooja Agarwal

3

2 references

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8 January 2020

Kyoung-Han Kim

4

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8 January 2020

Yonghong Zhu

5

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8 January 2020

Wei Zhu

6

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31 January 2017

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8 January 2020

Melanie Lebel

7

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31 January 2017

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8 January 2020

Chi Wa Cheng

8

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8 January 2020

Alejandra Guerchicoff

11

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31 January 2017

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8 January 2020

Shuk Han Cheng

15

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31 January 2017

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8 January 2020

Danny L Costantini

1

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8 January 2020

Eric P Arruda

2

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8 January 2020

Chong Y Park

9

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8 January 2020

Stephanie A Pierce

10

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8 January 2020

Guido D Pollevick

12

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8 January 2020

Toby Y Chan

13

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8 January 2020

M Golam Kabir

14

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8 January 2020

Deepak Srivastava

19

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8 January 2020

Gil J Gross

20

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8 January 2020

Chi-chung Hui

21

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8 January 2020

Peter H Backx

22

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8 January 2020

language of work or name

English

0 references

publication date

1 October 2005

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8 January 2020

2 references

31 January 2017

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8 January 2020

volume

123

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8 January 2020

issue

2

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8 January 2020

page(s)

347-358

1 reference

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The Iroquois homeobox gene, Irx5, is required for retinal cone bipolar cell development

8 January 2020

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1 reference

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A fundamental role for KChIPs in determining the molecular properties and trafficking of Kv4.2 potassium channels

17 March 2017

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Regulation of Kv4.3 current by KChIP2 splice variants: a component of native cardiac I(to)?

17 March 2017

1 reference

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Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis

17 March 2017

1 reference

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A defect in the Kv channel-interacting protein 2 (KChIP2) gene leads to a complete loss of I(to) and confers susceptibility to ventricular tachycardia

17 March 2017

1 reference

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A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease

17 March 2017

1 reference

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The molecular physiology of the cardiac transient outward potassium current (I(to)) in normal and diseased myocardium

17 March 2017

1 reference

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Cardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expression

17 March 2017

1 reference

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Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand

17 March 2017

1 reference

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Regional contributions of Kv1.4, Kv4.2, and Kv4.3 to transient outward K current in rat ventricle

17 March 2017

1 reference

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Molecular basis of transient outward potassium current downregulation in human heart failure: a decrease in Kv4.3 mRNA correlates with a reduction in current density

17 March 2017

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Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animals

17 March 2017

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What causes sudden death in heart failure?

17 March 2017

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Cellular basis and mechanism underlying normal and abnormal myocardial repolarization and arrhythmogenesis.

29 September 2017

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The prepattern transcription factor Irx2, a target of the FGF8/MAP kinase cascade, is involved in cerebellum formation

29 September 2017

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The Iroquois Homeobox Gene Irx2 Is Not Essential for Normal Development of the Heart and Midbrain-Hindbrain Boundary in Mice

29 September 2017

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Short QT Syndrome: a familial cause of sudden death

29 September 2017

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Regulatory modules in the developing heart.

29 September 2017

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29 September 2017

Genetics and arrhythmias

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Heterogeneous expression of voltage-gated potassium channels in the heart: roles in normal excitation and arrhythmias

29 September 2017

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Modulation of Kv4-encoded K( ) currents in the mammalian myocardium by neuronal calcium sensor-1.

29 September 2017

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Role of heteromultimers in the generation of myocardial transient outward K currents.

29 September 2017

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Transcriptional regulation of vertebrate cardiac morphogenesis

29 September 2017

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Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death

29 September 2017

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The Iroquois family of genes: from body building to neural patterning.

29 September 2017

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Role of the iroquois3 homeobox gene in organizer formation

29 September 2017

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Patterning the embryonic heart: identification of five mouse Iroquois homeobox genes in the developing heart

29 September 2017

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Four kinetically distinct depolarization-activated K currents in adult mouse ventricular myocytes

29 September 2017

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29 September 2017

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Modulation of Ca(2 ) release in cardiac myocytes by changes in repolarization rate: role of phase-1 action potential repolarization in excitation-contraction coupling

29 September 2017

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Amplified transmural dispersion of repolarization as the basis for arrhythmogenesis in a canine ventricular-wedge model of short-QT syndrome

3 June 2018

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Heterogeneous expression of repolarizing, voltage-gated K currents in adult mouse ventricles

27 November 2018

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The phosphoinositide 3-kinase inhibitor LY294002 enhances cardiac myocyte contractility via a direct inhibition of Ik,slow currents

27 November 2018

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GATA and FOG2 transcription factors differentially regulate the promoter for Kv4.2 K( ) channel gene in cardiac myocytes and PC12 cells

27 November 2018

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Cardiac electrophysiologic abnormalities in the CREBA133 transgenic mouse model of idiopathic dilated cardiomyopathy

27 November 2018

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Conversion of an extracellular Dpp/BMP morphogen gradient into an inverse transcriptional gradient.

27 November 2018

1 reference

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Concordant expression of KChIP2 mRNA, protein and transient outward current throughout the canine ventricle

27 November 2018

1 reference

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Correlation of repolarization of ventricular monophasic action potential with ECG in the murine heart

27 November 2018

1 reference

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A role for iro1 and iro7 in the establishment of an anteroposterior compartment of the ectoderm adjacent to the midbrain-hindbrain boundary.

27 November 2018

1 reference

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Expression of Irx6 during mouse morphogenesis.

27 November 2018

1 reference

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The Wnt-activated Xiro1 gene encodes a repressor that is essential for neural development and downregulates Bmp4.

27 November 2018

1 reference

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Expression of two novel mouse Iroquois homeobox genes during neurogenesis

27 November 2018

1 reference

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Molecular basis of transient outward K current diversity in mouse ventricular myocytes.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480411

Regulation of chamber-specific gene expression in the developing heart by Irx4.

27 November 2018

1 reference

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In vivo temporal and spatial distribution of depolarization and repolarization and the illusive murine T wave

27 November 2018

1 reference

12 December 2020

Targeted expression of a dominant-negative K(v)4.2 K( ) channel subunit in the mouse heart

1 reference

12 December 2020

Functional consequences of elimination of i(to,f) and i(to,s): early afterdepolarizations, atrioventricular block, and ventricular arrhythmias in mice lacking Kv1.4 and expressing a dominant-negative Kv4 alpha subunit

1 reference

12 December 2020

Myocardial infarction in rat eliminates regional heterogeneity of AP profiles, I(to) K( ) currents, and [Ca(2 )](i) transients

1 reference

12 December 2020

10.1016/J.CELL.2005.08.004

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16239150 AND SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

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8 January 2020

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