Psoriasiform dermatitis is driven by IL-36-mediated DC-keratinocyte crosstalk (Q28587108)

31 January 2017

title

Psoriasiform dermatitis is driven by IL-36-mediated DC-keratinocyte crosstalk (English)

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Interleukin 1 receptor-like 2

31 January 2017

main subject

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GOA release 2020-03-11

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8

Sabine Werner

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31 January 2017

Jan Kisielow

9

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Manfred Kopf

object named as

Manfred Kopf

10

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Jean-Christophe Renauld

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ORCID Public Data File 2021

Anthony J Coyle

6

object named as

Anthony J. Coyle

1 reference

31 January 2017

Luigi Tortola

1

1 reference

31 January 2017

Esther Rosenwald

2

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31 January 2017

Brian Abel

3

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31 January 2017

Hal Blumberg

4

1 reference

31 January 2017

Matthias Schäfer

5

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31 January 2017

Jean-Christoph Renauld

7

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31 January 2017

language of work or name

English

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publication date

1 November 2012

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Journal of Clinical Investigation

31 January 2017

published in

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31 January 2017

volume

122

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31 January 2017

issue

11

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31 January 2017

page(s)

3965–3976

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Interleukin-36 (IL-36) ligands require processing for full agonist (IL-36α, IL-36β, and IL-36γ) or antagonist (IL-36Ra) activity

31 January 2017

cites work

1 reference

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IL-36R ligands are potent regulators of dendritic and T cells

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17 March 2017

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17 March 2017

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17 March 2017

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Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)

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17 March 2017

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A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes

17 March 2017

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Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

17 March 2017

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Interleukin (IL)-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP to activate the pathway leading to NF-kappaB and MAPKs

17 March 2017

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Two novel IL-1 family members, IL-1 delta and IL-1 epsilon, function as an antagonist and agonist of NF-kappa B activation through the orphan IL-1 receptor-related protein 2

17 March 2017

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17 March 2017

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Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

7 April 2017

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Rorγt innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice

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29 September 2017

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29 September 2017

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Interleukin-36-receptor antagonist deficiency and generalized pustular psoriasis

29 September 2017

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Mutations in IL36RN/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis.

29 September 2017

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Cutting edge: Identification of a motile IL-17-producing gammadelta T cell population in the dermis

29 September 2017

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CCL20, γδ T cells, and IL-22 in corneal epithelial healing

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Skin immune sentinels in health and disease

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis

29 September 2017

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Latent TGFbeta1 overexpression in keratinocytes results in a severe psoriasis-like skin disorder

29 September 2017

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Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-alpha

29 September 2017

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Resolution of psoriasis upon blockade of IL-15 biological activity in a xenograft mouse model

29 September 2017

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Absence of IL-1 signaling and reduced inflammatory response in IL-1 type I receptor-deficient mice

29 September 2017

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Inflammatory skin disease in transgenic mice that express high levels of interleukin 1 alpha in basal epidermis

29 September 2017

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Generalized exacerbation of psoriasis associated with imiquimod cream treatment of superficial basal cell carcinomas

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484446

Psoriasis induced by topical imiquimod

3 June 2018

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IL-23 production by cosecretion of endogenous p19 and transgenic p40 in keratin 14/p40 transgenic mice: evidence for enhanced cutaneous immunity

3 June 2018

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IL-22 is required for imiquimod-induced psoriasiform skin inflammation in mice

3 June 2018

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Expression of interleukin (IL)-1 family members upon stimulation with IL-17 differs in keratinocytes derived from patients with psoriasis and healthy donors.

27 November 2018

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Cutting edge: crucial role of IL-1 and IL-23 in the innate IL-17 response of peripheral lymph node NK1.1- invariant NKT cells to bacteria.

27 November 2018

1 reference

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IL-1RL2 and its ligands contribute to the cytokine network in psoriasis.

27 November 2018

1 reference

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Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity.

27 November 2018

1 reference

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Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals

27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484446

27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484446

Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484446

In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: enhanced expression in psoriatic skin.

27 November 2018

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Psoriasis-like cutaneous inflammation in mice lacking interleukin-1 receptor antagonist

27 November 2018

1 reference

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Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses

27 November 2018

1 reference

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Inter-regulation of Th17 cytokines and the IL-36 cytokines in vitro and in vivo: implications in psoriasis pathogenesis

27 November 2018

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12 December 2020

c-Jun and JunB antagonistically control cytokine-regulated mesenchymal-epidermal interaction in skin

1 reference

12 December 2020

Human keratinocytes express functional Toll-like receptor 3, 4, 5, and 9

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12 December 2020

IL-22 is expressed by Th17 cells in an IL-23-dependent fashion, but not required for the development of autoimmune encephalomyelitis

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12 December 2020

Identifiers

DOI

10.1172/JCI63451

1 reference

1 reference

1 reference

1 reference