Disturbed cholesterol homeostasis in a peroxisome-deficient PEX2 knockout mouse model (Q28586335)

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14673138 AND SRC:MED&resulttype=core&format=json

22 December 2019

title

Disturbed cholesterol homeostasis in a peroxisome-deficient PEX2 knockout mouse model (English)

2 references

31 January 2017

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Peroxisomal biogenesis factor 2

22 December 2019

main subject

knockout mouse

0 references

1 reference

GOA release 2020-03-11

author

Werner J Kovacs

1

1 reference

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22 December 2019

author name string

Janis E Shackelford

2

1 reference

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22 December 2019

Khanichi N Tape

3

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22 December 2019

Michael J Richards

4

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22 December 2019

Phyllis L Faust

5

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22 December 2019

Steven J Fliesler

6

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22 December 2019

Skaidrite K Krisans

7

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22 December 2019

language of work or name

English

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publication date

1 January 2004

2 references

31 January 2017

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Molecular and Cellular Biology

22 December 2019

published in

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31 January 2017

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22 December 2019

volume

24

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31 January 2017

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22 December 2019

issue

1

2 references

31 January 2017

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22 December 2019

page(s)

1-13

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describes a project that uses

22 December 2019

ImageQuant

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11 June 2022

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inferred from PubMed Central ID database lookup

cites work

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Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover

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Absence of functional peroxisomes does not lead to deficiency of enzymes involved in cholesterol biosynthesis

17 March 2017

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17 March 2017

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The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

17 March 2017

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Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

17 March 2017

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ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport

17 March 2017

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Differential binding of proteins to peroxisomes in rat hepatoma cells: unique association of enzymes involved in isoprenoid metabolism

17 March 2017

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17 March 2017

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Farnesyl-diphosphate synthase is localized in peroxisomes

17 March 2017

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Mevalonate kinase is predominantly localized in peroxisomes and is defective in patients with peroxisome deficiency disorders

17 March 2017

1 reference

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SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

17 March 2017

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Evaluation of methods for the measurement of low-density lipoprotein cholesterol.

7 April 2017

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Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor

7 April 2017

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Central role of peroxisomes in isoprenoid biosynthesis

29 September 2017

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Nuclear hormone receptors and cholesterol trafficking: the orphans find a new home

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Expression of sterol regulatory element-binding protein 1c (SREBP-1c) mRNA in rat hepatoma cells requires endogenous LXR ligands

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

1 reference

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29 September 2017

1 reference

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Complete nucleotide sequence of cDNA and predicted amino acid sequence of rat acyl-CoA oxidase

29 September 2017

1 reference

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Normal cholesterol synthesis in human cells requires functional peroxisomes

29 September 2017

1 reference

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29 September 2017

Bile acid biosynthesis

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Mechanism of degradation of the steroid side chain in the formation of bile acids

29 September 2017

1 reference

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Isoprenoid biosynthesis is not compromised in a Zellweger syndrome mouse model

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303355

Bile acid induction of cytokine expression by macrophages correlates with repression of hepatic cholesterol 7alpha-hydroxylase

3 June 2018

1 reference

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Disruption of cholesterol 7alpha-hydroxylase gene in mice. I. Postnatal lethality reversed by bile acid and vitamin supplementation

3 June 2018

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Subcellular localization of squalene synthase in rat hepatic cells. Biochemical and immunochemical evidence

3 June 2018

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Tissue fractionation studies. 17. Intracellular distribution of monoamine oxidase, aspartate aminotransferase, alanine aminotransferase, D-amino acid oxidase and catalase in rat-liver tissue

3 June 2018

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Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge

3 June 2018

1 reference

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Increased cholesterol synthesis in Chinese hamster ovary cells deficient in peroxisomes

3 June 2018

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Role of the hepatic ABCA1 transporter in modulating intrahepatic cholesterol and plasma HDL cholesterol concentrations

3 June 2018

1 reference

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Inhibition of cholesterol absorption by SCH 58053 in the mouse is not mediated via changes in the expression of mRNA for ABCA1, ABCG5, or ABCG8 in the enterocyte

27 November 2018

1 reference

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27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells

27 November 2018

1 reference

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Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding

27 November 2018

1 reference

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Marked alteration of sterol metabolism and composition without compromising retinal development or function.

27 November 2018

1 reference

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Cholesterol biosynthesis in dermal fibroblasts from patients with metabolic disorders of peroxisomal origin

27 November 2018

1 reference

12 December 2020

Cholesterol synthesis in the vertebrate retina: effects of U18666A on rat retinal structure, photoreceptor membrane assembly, and sterol metabolism and composition

1 reference

12 December 2020

Reduced cellular cholesterol content in peroxisome-deficient fibroblasts is associated with impaired uptake of the patient's low density lipoprotein and with reduced cholesterol synthesis

1 reference

12 December 2020

Cholesterol biosynthesis in Zellweger syndrome: normal activity of mevalonate kinase, mevalonate-5'-pyrophosphate decarboxylase and IPP-isomerase in patients' fibroblasts but deficient mevalonate kinase activity in liver

1 reference

12 December 2020

Analysis of isoprenoid biosynthesis in peroxisomal-deficient Pex2 CHO cell lines

1 reference

12 December 2020

Marked reduction in bile acid synthesis in cholesterol 7alpha-hydroxylase-deficient mice does not lead to diminished tissue cholesterol turnover or to hypercholesterolemia

1 reference

12 December 2020

10.1128/MCB.24.1.1-13.2004

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14673138 AND SRC:MED&resulttype=core&format=json

22 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14673138 AND SRC:MED&resulttype=core&format=json

22 December 2019

2 references

31 January 2017