Reduced binding of protein phosphatase 2A to tau protein with frontotemporal dementia and parkinsonism linked to chromosome 17 mutations (Q28577828)

31 January 2017

title

Reduced binding of protein phosphatase 2A to tau protein with frontotemporal dementia and parkinsonism linked to chromosome 17 mutations (English)

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Frontotemporal dementia and parkinsonism linked to chromosome 17

31 January 2017

main subject

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frontotemporal dementia

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based on heuristic

inferred from title

parkinsonian syndrome

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M. Goedert

1

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31 January 2017

S. Satumtira

2

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31 January 2017

R. Jakes

3

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31 January 2017

M. J. Smith

4

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31 January 2017

C. Kamibayashi

5

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31 January 2017

C. L. White

6

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31 January 2017

E. Sontag

7

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31 January 2017

language of work or name

English

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publication date

1 November 2000

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Journal of Neurochemistry

31 January 2017

published in

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31 January 2017

volume

75

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31 January 2017

issue

5

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31 January 2017

page(s)

2155–2162

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Structure and novel exons of the human tau gene

31 January 2017

cites work

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Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding

21 January 2018

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Frontotemporal dementia and corticobasal degeneration in a family with a P301S mutation in tau.

21 January 2018

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The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology.

21 January 2018

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Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17

21 January 2018

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Missense and silent tau gene mutations cause frontotemporal dementia with parkinsonism-chromosome 17 type, by affecting multiple alternative RNA splicing regulatory elements

21 January 2018

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Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

21 January 2018

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p42 map kinase phosphorylation sites in microtubule-associated protein tau are dephosphorylated by protein phosphatase 2A1Implications for Alzheimer's disease

21 January 2018

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Tau gene mutation in familial progressive subcortical gliosis

21 January 2018

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Identification of a novel microtubule binding and assembly domain in the developmentally regulated inter-repeat region of tau.

21 January 2018

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Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

21 January 2018

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Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17.

21 January 2018

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Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

21 January 2018

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Separation of PP2A core enzyme and holoenzyme with monoclonal antibodies against the regulatory A subunit: abundant expression of both forms in cells

21 January 2018

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Stable expression in Chinese hamster ovary cells of mutated tau genes causing frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17)

21 January 2018

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Site-specific dephosphorylation of tau protein at Ser202/Thr205 in response to microtubule depolymerization in cultured human neurons involves protein phosphatase 2A.

21 January 2018

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Tau pathology in a family with dementia and a P301L mutation in tau.

21 January 2018

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Tau gene mutation G389R causes a tauopathy with abundant pick body-like inclusions and axonal deposits.

21 January 2018

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Accelerated filament formation from tau protein with specific FTDP-17 missense mutations.

21 January 2018

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Protein phosphatase 2A subunit assembly: the catalytic subunit carboxy terminus is important for binding cellular B subunit but not polyomavirus middle tumor antigen

21 January 2018

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Tau is a candidate gene for chromosome 17 frontotemporal dementia

21 January 2018

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Autosomal dominant dementia with widespread neurofibrillary tangles.

21 January 2018

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High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands

21 January 2018

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Regulation of the phosphorylation state and microtubule-binding activity of Tau by protein phosphatase 2A.

21 January 2018

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Molecular interactions among protein phosphatase 2A, tau, and microtubules. Implications for the regulation of tau phosphorylation and the development of tauopathies

21 January 2018

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Familial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filaments

21 January 2018

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Mutation in the tau gene in familial multiple system tauopathy with presenile dementia

21 January 2018

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Tau pathology in two Dutch families with mutations in the microtubule-binding region of tau

21 January 2018

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Phenotypic variation in hereditary frontotemporal dementia with tau mutations

21 January 2018

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Identification of kinase-phosphatase signaling modules composed of p70 S6 kinase-protein phosphatase 2A (PP2A) and p21-activated kinase-PP2A.

21 January 2018

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Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation

21 January 2018

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10.1046/J.1471-4159.2000.0752155.X

21 January 2018

Identifiers

DOI

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