Pin1 inhibition activates cyclin D and produces neurodegenerative pathology (Q28572716)

31 January 2017

title

Pin1 inhibition activates cyclin D and produces neurodegenerative pathology (English)

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31 January 2017

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Kutay Deniz Atabay

1

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31 January 2017

Arzu Karabay

2

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31 January 2017

language of work or name

English

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publication date

1 February 2012

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31 January 2017

5 May 2011

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21443524

full work available at URL

28 November 2024

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111/j.1471-4159.2011.07259.x

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https://api.crossref.org/works/10.1111/J.1471-4159.2011.07259.X

https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1471-4159.2011.07259.x

28 November 2024

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https://api.crossref.org/works/10.1111/J.1471-4159.2011.07259.X

Journal of Neurochemistry

28 November 2024

published in

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31 January 2017

volume

120

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31 January 2017

issue

3

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31 January 2017

page(s)

430–439

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Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms.

31 January 2017

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Prevalent overexpression of prolyl isomerase Pin1 in human cancers

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Regeneration and proliferation of embryonic and adult rat hippocampal neurons in culture

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Pin1 affects Tau phosphorylation in response to Abeta oligomers

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Induction of mitosis in mature neurons in central nervous system by sustained depolarization

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The neuronal cell cycle as a mechanism of pathogenesis in Alzheimer's disease

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Alternative functions of core cell cycle regulators in neuronal migration, neuronal maturation, and synaptic plasticity

21 January 2018

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The peptidylprolyl cis/trans-isomerase Pin1 modulates stress-induced dephosphorylation of Tau in neurons. Implication in a pathological mechanism related to Alzheimer disease

21 January 2018

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Phosphorylation of microtubule-associated protein tau is regulated by protein phosphatase 2A in mammalian brain. Implications for neurofibrillary degeneration in Alzheimer's disease.

21 January 2018

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Peptidyl-prolyl cis-trans isomerases, a superfamily of ubiquitous folding catalysts

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Selective inactivation of parvulin-like peptidyl-prolyl cis/trans isomerases by juglone.

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Divide and die: cell cycle events as triggers of nerve cell death.

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Prolyl isomerases and nuclear function

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Axonal growth is sensitive to the levels of katanin, a protein that severs microtubules

21 January 2018

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Inhibition of Pin1 reduces glutamate-induced perikaryal accumulation of phosphorylated neurofilament-H in neurons

21 January 2018

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The binding and phosphorylation of Thr231 is critical for Tau's hyperphosphorylation and functional regulation by glycogen synthase kinase 3beta

21 January 2018

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Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes

21 January 2018

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Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration.

21 January 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

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Pinning down cell signaling, cancer and Alzheimer's disease

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A human peptidyl-prolyl isomerase essential for regulation of mitosis

21 January 2018

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The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein

21 January 2018

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Pinning down proline-directed phosphorylation signaling

21 January 2018

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Adult neural stem cells in the mammalian central nervous system

21 January 2018

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A fluorescence vital assay for the recognition and quantification of excitotoxic cell death by necrosis and apoptosis using confocal microscopy on neurons in culture.

21 January 2018

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The cell cycle as a therapeutic target for Alzheimer's disease

21 January 2018

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The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production

21 January 2018

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Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC

21 January 2018

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PIN1 is an E2F target gene essential for Neu/Ras-induced transformation of mammary epithelial cells

21 January 2018

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Analyzing real-time PCR data by the comparative C(T) method

21 January 2018

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PIN1 promoter polymorphisms are associated with Alzheimer's disease.

21 January 2018

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Cell cycle activation and CNS injury.

21 January 2018

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Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysis

21 January 2018

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Role of cyclin D1 cytoplasmic sequestration in the survival of postmitotic neurons

21 January 2018

1 reference

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Increased cyclin D1 in vulnerable neurons in the hippocampus after ischaemia and epilepsy: a modulator of in vivo programmed cell death?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2011.07259.X

Neural cell cycle dysregulation and central nervous system diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2011.07259.X

Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage

21 January 2018

1 reference

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Cell division in the CNS: protective response or lethal event in post-mitotic neurons?

21 January 2018

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PIN1, the cell cycle and cancer.

21 January 2018

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Primary support cultures of hippocampal and substantia nigra neurons

21 January 2018

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Inverse association of Pin1 and tau accumulation in Alzheimer's disease hippocampus

21 January 2018

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Cyclin-dependent kinase 4 and cyclin D1 are required for excitotoxin-induced neuronal cell death in vivo.

28 November 2024

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https://api.crossref.org/works/10.1111/J.1471-4159.2011.07259.X

Cyclin D1 is an essential mediator of apoptotic neuronal cell death.

28 November 2024

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https://api.crossref.org/works/10.1111/J.1471-4159.2011.07259.X

Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis.

28 November 2024

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https://api.crossref.org/works/10.1111/J.1471-4159.2011.07259.X

Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease.

28 November 2024

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https://api.crossref.org/works/10.1111/J.1471-4159.2011.07259.X

28 November 2024

Identifiers

1 reference

31 January 2017

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