Inhibition of cyclin-dependent kinase 5 activity protects pancreatic beta cells from glucotoxicity (Q28571130)

31 January 2017

title

Inhibition of cyclin-dependent kinase 5 activity protects pancreatic beta cells from glucotoxicity (English)

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31 January 2017

3

Joel F. Habener

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31 January 2017

Mariano Ubeda

1

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31 January 2017

J. Michael Rukstalis

series ordinal

2

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31 January 2017

language of work or name

English

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publication date

29 September 2006

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Journal of Biological Chemistry

31 January 2017

published in

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31 January 2017

volume

281

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issue

39

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31 January 2017

page(s)

28858–28864

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Glucose-induced expression of the cyclin-dependent protein kinase 5 activator p35 involved in Alzheimer's disease regulates insulin gene transcription in pancreatic beta-cells

31 January 2017

cites work

1 reference

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Protective mechanism of glucose against alloxan-induced pancreatic beta-cell damage

21 January 2018

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The reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to high glucose concentration is associated with the loss of RIPE3b1 and STF-1 transcription factor expression

21 January 2018

1 reference

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Reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to a supraphysiologic glucose concentration is associated with loss of STF-1 transcription factor expression

21 January 2018

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Chronic hyperglycemia is associated with impaired glucose influence on insulin secretion. A study in normal rats using chronic in vivo glucose infusions

21 January 2018

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Cdk5, a therapeutic target for Alzheimer's disease?

21 January 2018

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Cdk5 deregulation in the pathogenesis of Alzheimer's disease

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Oxidative stress induces nucleo-cytoplasmic translocation of pancreatic transcription factor PDX-1 through activation of c-Jun NH(2)-terminal kinase.

21 January 2018

1 reference

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Oxidative stress-mediated, post-translational loss of MafA protein as a contributing mechanism to loss of insulin gene expression in glucotoxic beta cells

21 January 2018

1 reference

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Differential expression of the insulin gene transcriptional repressor CCAAT/enhancer-binding protein beta and transactivator islet duodenum homeobox-1 in rat pancreatic beta cells during the development of diabetes mellitus

21 January 2018

1 reference

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Pancreatic beta-cell-specific repression of insulin gene transcription by CCAAT/enhancer-binding protein beta. Inhibitory interactions with basic helix-loop-helix transcription factor E47.

21 January 2018

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Stress-induced binding of the transcriptional factor CHOP to a novel DNA control element

21 January 2018

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Reconstitution of glucotoxic HIT-T15 cells with somatostatin transcription factor-1 partially restores insulin promoter activity

21 January 2018

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Chronic exposure of betaTC-6 cells to supraphysiologic concentrations of glucose decreases binding of the RIPE3b1 insulin gene transcription activator

21 January 2018

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Cyclin-dependent kinase 5 in amyotrophic lateral sclerosis

21 January 2018

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Role of oxidative stress in pancreatic beta-cell dysfunction

21 January 2018

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Up-regulation of cDK5/p35 by oxidative stress in human neuroblastoma IMR-32 cells

21 January 2018

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Modulation of the JNK and p38 pathways by cdk5 protein kinase in a transgenic mouse model of Alzheimer's disease

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M604690200

1 reference

Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017