Transforming growth factor-beta prevents osteoblast apoptosis induced by skeletal unloading via PI3K/Akt, Bcl-2, and phospho-Bad signaling (Q28569490)

31 January 2017

title

Transforming growth factor-beta prevents osteoblast apoptosis induced by skeletal unloading via PI3K/Akt, Bcl-2, and phospho-Bad signaling (English)

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31 January 2017

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Cécilie Dufour

1

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31 January 2017

Xavier Holy

series ordinal

2

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31 January 2017

Pierre J. Marie

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3

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31 January 2017

publication date

1 April 2008

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American Journal of Physiology - Endocrinology and Metabolism

31 January 2017

published in

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volume

294

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issue

4

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31 January 2017

page(s)

E794–801

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Transforming growth factor beta2 inhibits adipocyte differentiation induced by skeletal unloading in rat bone marrow stroma

31 January 2017

cites work

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Transforming growth factor-beta inhibits CCAAT/enhancer-binding protein expression and PPARgamma activity in unloaded bone marrow stromal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Mechanotransduction: all signals point to cytoskeleton, matrix, and integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts by beta-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Adhesion-dependent cell mechanosensitivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Extracellular matrix proteoglycans control the fate of bone marrow stromal cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

The Wnt antagonist secreted frizzled-related protein-1 controls osteoblast and osteocyte apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Mechanical strain on osteoblasts activates autophosphorylation of focal adhesion kinase and proline-rich tyrosine kinase 2 tyrosine sites involved in ERK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Control of TGF-beta receptor expression in bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

TGF-beta1 inhibits multiple caspases induced by TNF-alpha in murine osteoblastic MC3T3-E1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Extracellular matrix-integrin interactions in osteoblast function and tissue remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Cellular survival: a play in three Akts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Fibroblast growth factor-2 induces osteoblast survival through a phosphatidylinositol 3-kinase-dependent, -beta-catenin-independent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Disorders associated with acute rapid and severe bone loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Apoptosis and survival of osteoblast-like cells are regulated by surface attachment

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Bone morphogenetic protein-2 promotes osteoblast apoptosis through a Smad-independent, protein kinase C-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

TGFbeta1 and TGFbeta2 mRNA and protein expression in human bone samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Osteoblast apoptosis and bone turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Anchorage-dependent ERK signaling--mechanisms and consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Signal transduction and mechanical stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Cbl-mediated ubiquitination of alpha5 integrin subunit mediates fibronectin-dependent osteoblast detachment and apoptosis induced by FGFR2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Matrix metalloproteinase-dependent activation of latent transforming growth factor-beta controls the conversion of osteoblasts into osteocytes by blocking osteoblast apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Role of the Akt/FoxO3a pathway in TGF-beta1-mediated mesangial cell dysfunction: a novel mechanism related to diabetic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Transforming growth factor-beta1 to the bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

alpha5beta1 integrin protects intestinal epithelial cells from apoptosis through a phosphatidylinositol 3-kinase and protein kinase B-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Systemic administration of transforming growth factor-beta 2 prevents the impaired bone formation and osteopenia induced by unloading in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Role of growth factors in osteoblast alterations induced by skeletal unloading in rats

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1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

A signaling pathway from the alpha5beta1 and alpha(v)beta3 integrins that elevates bcl-2 transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

The hindlimb unloading rat model: literature overview, technique update and comparison with space flight data

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

TGF-beta1-stimulated osteoblasts require intracellular calcium signaling for enhanced alpha5 integrin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Mechanical loading: biphasic osteocyte survival and targeting of osteoclasts for bone destruction in rat cortical bone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Mechanical stimulation prevents osteocyte apoptosis: requirement of integrins, Src kinases, and ERKs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

The mode of mechanical integrin stressing controls intracellular signaling in osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Upregulation of two BH3-only proteins, Bmf and Bim, during TGF beta-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Structure—Function Analysis of Bcl-2 Family Proteins

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1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Transforming growth factor-beta regulates collagen gel contraction by increasing alpha 2 beta 1 integrin expression in osteogenic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Skeletal unloading induces resistance to insulin-like growth factor-I (IGF-I) by inhibiting activation of the IGF-I signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Dual role for TGF-beta1 in apoptosis

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1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Role of integrins in cellular responses to mechanical stress and adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Mechanically strained cells of the osteoblast lineage organize their extracellular matrix through unique sites of alphavbeta3-integrin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Regulation of apoptosis in osteoclasts and osteoblastic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

Rat tail suspension reduces messenger RNA level for growth factors and osteopontin and decreases the osteoblastic differentiation of bone marrow stromal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

The alpha 5 beta 1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00791.2007

10.1152/AJPENDO.00791.2007

21 January 2018

Identifiers

DOI

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31 January 2017

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