A small molecule p75(NTR) ligand protects neurogenesis after traumatic brain injury (Q28568991)

31 January 2017

title

A small molecule p75(NTR) ligand protects neurogenesis after traumatic brain injury (English)

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31 January 2017

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Jian Shi

1

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31 January 2017

Frank M. Longo

series ordinal

2

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31 January 2017

Stephen M. Massa

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3

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31 January 2017

publication date

1 November 2013

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31 January 2017

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31 January 2017

volume

31

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31 January 2017

issue

11

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31 January 2017

page(s)

2561–2574

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Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury

31 January 2017

cites work

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Modulation of p75-dependent motor neuron death by a small non-peptidyl mimetic of the neurotrophin loop 1 domain

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Signaling of the neurotrophin receptor p75 in relation to Alzheimer's disease

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The p75 neurotrophin receptor promotes amyloid-beta(1-42)-induced neuritic dystrophy in vitro and in vivo

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Abeta(1-42) stimulates adult SVZ neurogenesis through the p75 neurotrophin receptor

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ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury

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p75 neurotrophin receptor signaling in nervous system injury and degeneration: paradox and opportunity

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Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease

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Dissecting the diverse actions of pro- and mature neurotrophins

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The p75 neurotrophin receptor

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Small molecule modulation of p75 neurotrophin receptor functions

21 January 2018

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p75 neurotrophin receptor expression defines a population of BDNF-responsive neurogenic precursor cells

21 January 2018

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The p75 neurotrophin receptor regulates hippocampal neurogenesis and related behaviours.

21 January 2018

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The p75 neurotrophin receptor is expressed by adult mouse dentate progenitor cells and regulates neuronal and non-neuronal cell genesis

21 January 2018

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Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75.

21 January 2018

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Immunohistological markers for staging neurogenesis in adult hippocampus.

21 January 2018

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Mechanisms and functional implications of adult neurogenesis

21 January 2018

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Adult neurogenesis in the mammalian brain: significant answers and significant questions

21 January 2018

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Different polysialic acid-neural cell adhesion molecule expression patterns in distinct types of mossy fiber boutons in the adult hippocampus

21 January 2018

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Expression patterns of immature neuronal markers PSA-NCAM, CRMP-4 and NeuroD in the hippocampus of young adult and aged rodents

21 January 2018

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Morris water maze learning in two rat strains increases the expression of the polysialylated form of the neural cell adhesion molecule in the dentate gyrus but has no effect on hippocampal neurogenesis

21 January 2018

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Selective learning and memory impairments in mice deficient for polysialylated NCAM in adulthood

21 January 2018

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Hippocampal up-regulation of NCAM expression and polysialylation plays a key role on spatial memory

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Upregulation of polysialylated neural cell adhesion molecule in the dorsal hippocampus after contextual fear conditioning is involved in long-term memory formation.

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Ventromedial temporal lobe pathology in dementia, brain trauma, and schizophrenia

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Dentate gyrus neurogenesis, integration and microRNAs

21 January 2018

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Temporally specified genetic ablation of neurogenesis impairs cognitive recovery after traumatic brain injury

21 January 2018

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Optical controlling reveals time-dependent roles for adult-born dentate granule cells.

21 January 2018

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Neurogenesis and hippocampal plasticity in adult brain.

21 January 2018

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Small, nonpeptide p75NTR ligands induce survival signaling and inhibit proNGF-induced death.

21 January 2018

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Small molecule, non-peptide p75 ligands inhibit Abeta-induced neurodegeneration and synaptic impairment

21 January 2018

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Anti-cancer drug induced neurotoxicity and identification of Rho pathway signaling modulators as potential neuroprotectants

21 January 2018

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Oral administration of a small molecule targeted to block proNGF binding to p75 promotes myelin sparing and functional recovery after spinal cord injury

21 January 2018

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Small molecule p75NTR ligand prevents cognitive deficits and neurite degeneration in an Alzheimer's mouse model.

21 January 2018

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Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents

21 January 2018

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Intranasal administration with NAD profoundly decreases brain injury in a rat model of transient focal ischemia

21 January 2018

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Injury-induced neurogenesis in Bax-deficient mice: evidence for regulation by voltage-gated potassium channels

21 January 2018

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Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system

21 January 2018

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Bax limits adult neural stem cell persistence through caspase and IP3 receptor activation

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Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons

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Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS.

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Microglial activation induced by brain trauma is suppressed by post-injury treatment with a PARP inhibitor

21 January 2018

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Buoyant density gradient fractionation and flow cytometric analysis of embryonic rat cortical neurons and progenitor cells

21 January 2018

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Developments of a water-maze procedure for studying spatial learning in the rat

21 January 2018

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TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment

21 January 2018

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p75NTR immunoreactivity in the rat dentate gyrus is mostly within presynaptic profiles but is also found in some astrocytic and postsynaptic profiles

21 January 2018

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Role of the cholinergic system in regulating survival of newborn neurons in the adult mouse dentate gyrus and olfactory bulb

21 January 2018

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SOX2 functions to maintain neural progenitor identity

21 January 2018

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Inflammatory Blockade Restores Adult Hippocampal Neurogenesis

21 January 2018

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Inflammation is detrimental for neurogenesis in adult brain

21 January 2018

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Long-term upregulation of inflammation and suppression of cell proliferation in the brain of adult rats exposed to traumatic brain injury using the controlled cortical impact model

21 January 2018

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IGF-I instructs multipotent adult neural progenitor cells to become oligodendrocytes

21 January 2018

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Differential properties of adult rat and mouse brain-derived neural stem/progenitor cells

21 January 2018

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Neurotrophins inhibit major histocompatibility class II inducibility of microglia: involvement of the p75 neurotrophin receptor

21 January 2018

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Neurotrophins regulate proliferation and survival of two microglial cell lines in vitro

21 January 2018

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Suppression of immunodeficiency virus-associated neural damage by the p75 neurotrophin receptor ligand, LM11A-31, in an in vitro feline model

21 January 2018

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Alterations in hippocampal neurogenesis following traumatic brain injury in mice

21 January 2018

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Selective death of newborn neurons in hippocampal dentate gyrus following moderate experimental traumatic brain injury

21 January 2018

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Brain remodeling due to neuronal and astrocytic proliferation after controlled cortical injury in mice.

21 January 2018

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Forebrain neurogenesis after focal Ischemic and traumatic brain injury

21 January 2018

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Traumatic brain injury-induced hippocampal neurogenesis requires activation of early nestin-expressing progenitors.

21 January 2018

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Brain-derived neurotrophic factor signaling does not stimulate subventricular zone neurogenesis in adult mice and rats

21 January 2018

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p75 neurotrophin receptor regulates basal and fluoxetine-stimulated hippocampal neurogenesis

21 January 2018

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Time-lapse imaging reveals symmetric neurogenic cell division of GFAP-expressing progenitors for expansion of postnatal dentate granule neurons

21 January 2018

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Brain-derived neurotrophic factor in traumatic brain injury, post-traumatic stress disorder, and their comorbid conditions: role in pathogenesis and treatment

21 January 2018

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Brain-derived neurotrophic factor (BDNF) has proliferative effects on neural stem cells through the truncated TRK-B receptor, MAP kinase, AKT, and STAT-3 signaling pathways

21 January 2018

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BDNF promotes differentiation and maturation of adult-born neurons through GABAergic transmission

21 January 2018

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Simvastatin-mediated upregulation of VEGF and BDNF, activation of the PI3K/Akt pathway, and increase of neurogenesis are associated with therapeutic improvement after traumatic brain injury

21 January 2018

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Erythropoietin promotes neurovascular remodeling and long-term functional recovery in rats following traumatic brain injury

21 January 2018

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Effects of erythropoietin on reducing brain damage and improving functional outcome after traumatic brain injury in mice

21 January 2018

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Treatment of traumatic brain injury with thymosin β₄ in rats

21 January 2018

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Impact of inhibition of erythropoietin treatment-mediated neurogenesis in the dentate gyrus of the hippocampus on restoration of spatial learning after traumatic brain injury

21 January 2018

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Sequential activation of p75 and TrkB is involved in dendritic development of subventricular zone-derived neuronal progenitors in vitro

21 January 2018

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