GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence (Q28567229)

31 January 2017

title

GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence (English)

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31 January 2017

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Irmgard Tegeder

1

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Jörn Lötsch

object named as

Jörn Lötsch

21

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David Goldman

object named as

David Goldman

15

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Inna Belfer

5

object named as

Inna Belfer

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31 January 2017

24

Gerd Geisslinger

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Steven J. Atlas

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26

Clifford J. Woolf

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31 January 2017

Michael Costigan

2

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31 January 2017

Robert S. Griffin

3

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31 January 2017

Andrea Abele

4

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31 January 2017

Helmut Schmidt

6

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31 January 2017

Corina Ehnert

7

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31 January 2017

Jemiel Nejim

8

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31 January 2017

Claudiu Marian

9

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Joachim Scholz

10

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31 January 2017

Tianxia Wu

11

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31 January 2017

Andrew Allchorne

12

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31 January 2017

Luda Diatchenko

13

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31 January 2017

Alexander M. Binshtok

14

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31 January 2017

Jan Adolph

16

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Swetha Sama

17

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William A. Carlezon

19

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Aram Parsegian

20

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Roger B. Fillingim

22

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31 January 2017

William Maixner

23

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31 January 2017

Mitchell B. Max

25

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31 January 2017

language of work or name

English

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publication date

1 November 2006

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31 January 2017

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31 January 2017

volume

12

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31 January 2017

issue

11

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31 January 2017

page(s)

1269–1277

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Role of neurotransmitters in sensitization of pain responses

31 January 2017

cites work

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7 January 2021

Evidence for a central component of post-injury pain hypersensitivity

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7 January 2021

Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord.

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Chronic pain and medullary descending facilitation

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Transcriptional and posttranslational plasticity and the generation of inflammatory pain

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Voltage-gated sodium channels and pain pathways

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Src, a molecular switch governing gain control of synaptic transmission mediated by N-methyl-D-aspartate receptors

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Role of the immune system in chronic pain.

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Blocking caspase activity prevents transsynaptic neuronal apoptosis and the loss of inhibition in lamina II of the dorsal horn after peripheral nerve injury.

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7 January 2021

Heritability of nociception I: responses of 11 inbred mouse strains on 12 measures of nociception

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Genetic basis for individual variations in pain perception and the development of a chronic pain condition

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7 January 2021

Structural, psychological, and genetic influences on low back and neck pain: A study of adult female twins

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7 January 2021

Replicate high-density rat genome oligonucleotide microarrays reveal hundreds of regulated genes in the dorsal root ganglion after peripheral nerve injury

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7 January 2021

Tetrahydrobiopterin biosynthesis, regeneration and functions

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7 January 2021

Induction of inducible nitric oxide synthase and its corresponding tetrahydrobiopterin-cofactor-synthesizing enzyme GTP-cyclohydrolase I during cutaneous wound repair

1 reference

7 January 2021

Glial cell line-derived neurotrophic factor up-regulates GTP-cyclohydrolase I activity and tetrahydrobiopterin levels in primary dopaminergic neurones

1 reference

7 January 2021

Phosphorylation of GTP cyclohydrolase I and modulation of its activity in rodent mast cells. GTP cyclohydrolase I hyperphosphorylation is coupled to high affinity IgE receptor signaling and involves protein kinase C.

1 reference

7 January 2021

Crystal structure of the stimulatory complex of GTP cyclohydrolase I and its feedback regulatory protein GFRP.

1 reference

7 January 2021

Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene

1 reference

7 January 2021

Mutations in the sepiapterin reductase gene cause a novel tetrahydrobiopterin-dependent monoamine-neurotransmitter deficiency without hyperphenylalaninemia

1 reference

7 January 2021

Spared nerve injury: an animal model of persistent peripheral neuropathic pain

1 reference

7 January 2021

Biosynthesis of pteridines. Reaction mechanism of GTP cyclohydrolase I

1 reference

7 January 2021

Activating transcription factor 3 (ATF3) induction by axotomy in sensory and motoneurons: A novel neuronal marker of nerve injury

1 reference

7 January 2021

The mechanism of potent GTP cyclohydrolase I inhibition by 2,4-diamino-6-hydroxypyrimidine: requirement of the GTP cyclohydrolase I feedback regulatory protein

1 reference

7 January 2021

GTP cyclohydrolase I inhibition by the prototypic inhibitor 2, 4-diamino-6-hydroxypyrimidine. Mechanisms and unanticipated role of GTP cyclohydrolase I feedback regulatory protein

1 reference

7 January 2021

Antidepressant-like effects of kappa-opioid receptor antagonists in the forced swim test in rats

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7 January 2021

Tetrahydro-sepiapterin is an intermediate in tetrahydrobiopterin biosynthesis

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7 January 2021

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7 January 2021

The Maine Lumbar Spine Study, Part II. 1-year outcomes of surgical and nonsurgical management of sciatica.

1 reference

7 January 2021

Long-term outcomes of surgical and nonsurgical management of sciatica secondary to a lumbar disc herniation: 10 year results from the maine lumbar spine study

1 reference

7 January 2021

Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals

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7 January 2021

Characterization of GTP cyclohydrolase I gene expression in the human neuroblastoma SKN-BE(2)M17: enhanced transcription in response to cAMP is conferred by the proximal promoter

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7 January 2021

Identification and characterization of basal and cyclic AMP response elements in the promoter of the rat GTP cyclohydrolase I gene

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7 January 2021

S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding

1 reference

7 January 2021

A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds

1 reference

7 January 2021

Reduced inflammatory hyperalgesia with preservation of acute thermal nociception in mice lacking cGMP-dependent protein kinase I.

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7 January 2021

Cyclic GMP pathway is critical for inducing long-term sensitization of nociceptive sensory neurons

1 reference

7 January 2021

cGMP/protein kinase G-dependent potentiation of glutamatergic transmission induced by nitric oxide in immature rat rostral ventrolateral medulla neurons in vitro

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7 January 2021

Tetrahydrobiopterin is released from and causes preferential death of catecholaminergic cells by oxidative stress

1 reference

7 January 2021

Stimulating effect of 6R-tetrahydrobiopterin on Ca2 channels in neurons of rat dorsal motor nucleus of the vagus

1 reference

7 January 2021

Neuropathic pain and spinal microglia: a big problem from molecules in "small" glia

1 reference

7 January 2021

High mutation rate in dopa-responsive dystonia: detection with comprehensive GCHI screening

1 reference

7 January 2021

COMT val158met genotype affects mu-opioid neurotransmitter responses to a pain stressor

1 reference

7 January 2021

The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans

1 reference

7 January 2021

Characteristics and prediction of early pain after laparoscopic cholecystectomy

1 reference

7 January 2021

From acute to chronic pain after laparoscopic cholecystectomy: a prospective follow-up analysis

1 reference

7 January 2021

Removal of GABAergic inhibition facilitates polysynaptic A fiber-mediated excitatory transmission to the superficial spinal dorsal horn

1 reference

7 January 2021

Cluster analysis of multiple experimental pain modalities

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7 January 2021