Requirement for Akt (protein kinase B) in insulin-induced activation of glycogen synthase and phosphorylation of 4E-BP1 (PHAS-1) (Q28564335)

31 January 2017

title

Requirement for Akt (protein kinase B) in insulin-induced activation of glycogen synthase and phosphorylation of 4E-BP1 (PHAS-1) (English)

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31 January 2017

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M. Takata

1

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31 January 2017

W. Ogawa

2

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31 January 2017

T. Kitamura

3

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31 January 2017

Y. Hino

4

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31 January 2017

S. Kuroda

5

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31 January 2017

K. Kotani

6

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31 January 2017

A. Klip

7

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31 January 2017

A. C. Gingras

8

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31 January 2017

N. Sonenberg

9

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31 January 2017

M. Kasuga

10

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31 January 2017

language of work or name

English

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publication date

16 July 1999

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Journal of Biological Chemistry

31 January 2017

published in

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31 January 2017

volume

274

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31 January 2017

issue

29

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31 January 2017

page(s)

20611–20618

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Role of binding proteins to IRS-1 in insulin signalling

31 January 2017

cites work

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Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

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A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

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Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport

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Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B

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Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

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Regulation of protein kinase C zeta by PI 3-kinase and PDK-1

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Platelet-derived growth factor activates protein kinase C epsilon through redundant and independent signaling pathways involving phospholipase C gamma or phosphatidylinositol 3-kinase

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Activation of protein kinase C (alpha, beta, and zeta) by insulin in 3T3/L1 cells. Transfection studies suggest a role for PKC-zeta in glucose transport

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Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes

21 January 2018

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Insulin activates a p21-activated kinase in muscle cells via phosphatidylinositol 3-kinase

21 January 2018

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The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote

21 January 2018

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Inhibition of phosphatidylinositol 3-kinase activity by adenovirus-mediated gene transfer and its effect on insulin action

21 January 2018

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Phosphatidylinositol 3-kinase mediates epidermal growth factor-induced activation of the c-Jun N-terminal kinase signaling pathway.

21 January 2018

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Ras-independent and wortmannin-sensitive activation of glycogen synthase by insulin in Chinese hamster ovary cells

21 January 2018

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Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein-S6 kinase

21 January 2018

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Potential role of protein kinase B in insulin-induced glucose transport, glycogen synthesis, and protein synthesis

21 January 2018

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Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

21 January 2018

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The mRNA 5' cap-binding protein eIF4E and control of cell growth

21 January 2018

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PHAS-I as a link between mitogen-activated protein kinase and translation initiation

21 January 2018

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Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

21 January 2018

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4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

21 January 2018

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Construction and characterization of a conditionally active version of the serine/threonine kinase Akt.

21 January 2018

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Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB.

21 January 2018

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Requirement of the serine-threonine kinase Akt for heat treatment-induced activation of p70 S6 kinase

21 January 2018

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Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha

21 January 2018

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A human protein kinase Bgamma with regulatory phosphorylation sites in the activation loop and in the C-terminal hydrophobic domain

21 January 2018

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Cap-binding protein (eukaryotic initiation factor 4E) and 4E-inactivating protein BP-1 independently regulate cap-dependent translation

21 January 2018

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Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome

21 January 2018

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

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The role of protein phosphorylation in neural and hormonal control of cellular activity

21 January 2018

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes.

21 January 2018

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Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway

21 January 2018

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Molecular cloning and characterization of a novel p38 mitogen-activated protein kinase

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.274.29.20611

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