ALK activation induces Shc and FRS2 recruitment: Signaling and phenotypic outcomes in PC12 cells differentiation (Q28564190)

31 January 2017

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25 December 2019

title

ALK activation induces Shc and FRS2 recruitment: Signaling and phenotypic outcomes in PC12 cells differentiation (English)

2 references

31 January 2017

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3

1 reference

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25 December 2019

author name string

Joffrey Degoutin

series ordinal

1

2 references

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25 December 2019

Marc Vigny

series ordinal

2

2 references

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language of work or name

English

0 references

publication date

25 January 2007

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25 December 2019

2 references

31 January 2017

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25 December 2019

volume

581

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issue

4

2 references

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25 December 2019

page(s)

727-734

1 reference

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Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system

25 December 2019

cites work

1 reference

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ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)

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Identification and characterization of DAlk: a novel Drosophila melanogaster RTK which drives ERK activation in vivo

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Identification of anaplastic lymphoma kinase as a receptor for the growth factor pleiotrophin

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Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types

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Expression and functional analysis of the anaplastic lymphoma kinase (ALK) gene in tumor cell lines

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Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines

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ALK receptor tyrosine kinase promotes cell growth and neurite outgrowth

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Activation and inhibition of anaplastic lymphoma kinase receptor tyrosine kinase by monoclonal antibodies and absence of agonist activity of pleiotrophin.

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Characterization of the expression of the ALK receptor tyrosine kinase in mice

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Activation of anaplastic lymphoma kinase receptor tyrosine kinase induces neuronal differentiation through the mitogen-activated protein kinase pathway

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Role of the subcellular localization of ALK tyrosine kinase domain in neuronal differentiation of PC12 cells

21 January 2018

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Signaling Through Scaffold, Anchoring, and Adaptor Proteins

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A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway

21 January 2018

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Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins

21 January 2018

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The signaling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. A model for discriminating proliferation and differentiation

21 January 2018

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Identification of SNT/FRS2 docking site on RET receptor tyrosine kinase and its role for signal transduction

21 January 2018

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Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascade

21 January 2018

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Potential involvement of FRS2 in insulin signaling

21 January 2018

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Overexpression of the signaling adapter FRS2 reconstitutes the cell cycle deficit of a nerve growth factor non-responsive TrkA receptor mutant.

21 January 2018

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Multiple effector domains within SNT1 coordinate ERK activation and neuronal differentiation of PC12 cells

21 January 2018

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FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors

21 January 2018

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Critical role for the docking-protein FRS2 alpha in FGF receptor-mediated signal transduction pathways

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Association of the signaling adaptor FRS2 with fibroblast growth factor receptor 1 (Fgfr1) is mediated by alternative splicing of the juxtamembrane domain

21 January 2018

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Anaplastic lymphoma kinase is a dependence receptor whose proapoptotic functions are activated by caspase cleavage.

21 January 2018

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Characterization of the transforming activity of p80, a hyperphosphorylated protein in a Ki-1 lymphoma cell line with chromosomal translocation t(2;5)

21 January 2018

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Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

21 January 2018

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Nerve growth factor-induced alteration in the response of PC12 pheochromocytoma cells to epidermal growth factor

21 January 2018

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PC12 cells overexpressing the insulin receptor undergo insulin-dependent neuronal differentiation

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Identifiers

DOI

2 references

31 January 2017

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25 December 2019

2 references

31 January 2017