Phosphatidylinositol binding clathrin assembly protein (Q28558333)

Phosphoinositide-binding clathrin adaptor, domain 2

1 reference

Phosphatidylinositol-binding clathrin assembly protein

1 reference

inferred from GOA cell component → membrane

membrane protein

1 reference

based on heuristic

AP180 N-terminal homology (ANTH) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

ENTH domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

1 January 2018

SNARE motif-mediated sorting of synaptobrevin by the endocytic adaptors clathrin assembly lymphoid myeloid leukemia (CALM) and AP180 at synapses

http://www.ebi.ac.uk/QuickGO/annotations?protein=O55012&geneProductId=UniProtKB:O55012

protein binding

1 reference

14 February 2019

The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

phospholipid binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

1 reference

14 February 2019

phosphatidylinositol-4,5-bisphosphate binding

1 reference

1 January 2018

CALM regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature

http://www.ebi.ac.uk/QuickGO/annotations?protein=O55012&geneProductId=UniProtKB:O55012

SH3 domain binding

1 reference

14 February 2019

Properties of GST-CALM expressed in E. coli

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

clathrin binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

14 February 2019

14 February 2019

Simultaneous binding of PtdIns(4,5)P2 and clathrin by AP180 in the nucleation of clathrin lattices on membranes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

identical protein binding

1 reference

14 February 2019

The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

SNARE binding

1-phosphatidylinositol binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

3 references

14 February 2019

14 February 2019

Simultaneous binding of PtdIns(4,5)P2 and clathrin by AP180 in the nucleation of clathrin lattices on membranes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

phosphatidylinositol-4,5-bisphosphate binding

clathrin heavy chain binding

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

cell component

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

1 reference

14 February 2019

endosome

1 reference

14 February 2019

Clathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

Golgi apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

1 reference

14 February 2019

plasma membrane

synaptic vesicle

1 reference

1 January 2018

AP180 and CALM in the developing hippocampus: expression at the nascent synapse and localization to trafficking organelles

http://www.ebi.ac.uk/QuickGO/annotations?protein=O55012&geneProductId=UniProtKB:O55012

postsynaptic density

1 reference

14 February 2019

AP180 and CALM in the developing hippocampus: expression at the nascent synapse and localization to trafficking organelles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

1 reference

14 February 2019

clathrin-coated vesicle

http://www.ebi.ac.uk/QuickGO/annotations?protein=O55012&geneProductId=UniProtKB:O55012

5 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O55012&geneProductId=UniProtKB:O55012

1 January 2018

1 January 2018

Clathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neurons

http://www.ebi.ac.uk/QuickGO/annotations?protein=O55012&geneProductId=UniProtKB:O55012

1 January 2018

Purification of clathrin assembly protein from rat liver

http://www.ebi.ac.uk/QuickGO/annotations?protein=O55012&geneProductId=UniProtKB:O55012

1 January 2018

AP180 and CALM in the developing hippocampus: expression at the nascent synapse and localization to trafficking organelles

http://www.ebi.ac.uk/QuickGO/annotations?protein=O55012&geneProductId=UniProtKB:O55012

intrinsic component of membrane

1 reference

14 February 2019

CALM regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

cytoplasmic vesicle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

1 reference

14 February 2019

vesicle

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

presynaptic membrane

neuron projection

1 reference

14 February 2019

Clathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

synapse

1 reference

14 February 2019

Synaptic distribution of the endocytic accessory proteins AP180 and CALM

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

neurofibrillary tangle

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

Schaffer collateral - CA1 synapse

1 reference

14 February 2019

Synaptic distribution of the endocytic accessory proteins AP180 and CALM

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

parallel fiber to Purkinje cell synapse

1 reference

14 February 2019

Synaptic distribution of the endocytic accessory proteins AP180 and CALM

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

postsynapse

1 reference

14 February 2019

Synaptic distribution of the endocytic accessory proteins AP180 and CALM

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

extrinsic component of presynaptic endocytic zone membrane

1 reference

1 January 2018

Synaptic distribution of the endocytic accessory proteins AP180 and CALM

http://www.ebi.ac.uk/QuickGO/annotations?protein=O55012&geneProductId=UniProtKB:O55012

plasma membrane

Clathrin and clathrin-accessory proteins in rat kidney cortex epithelia

3 references

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=O55012&geneProductId=UniProtKB:O55012

14 January 2019

Clathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neurons

http://www.ebi.ac.uk/QuickGO/annotations?protein=O55012&geneProductId=UniProtKB:O55012

14 January 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O55012&geneProductId=UniProtKB:O55012

clathrin-coated pit

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

14 February 2019

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

synaptic vesicle

clathrin-coated vesicle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

14 February 2019

14 February 2019

Purification of clathrin assembly protein from rat liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

14 February 2019

Clathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

14 February 2019

AP180 and CALM in the developing hippocampus: expression at the nascent synapse and localization to trafficking organelles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

presynaptic membrane

AP180 and CALM in the developing hippocampus: expression at the nascent synapse and localization to trafficking organelles

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

14 February 2019

Synaptic distribution of the endocytic accessory proteins AP180 and CALM

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

4 references

14 February 2019

14 February 2019

Clathrin and clathrin-accessory proteins in rat kidney cortex epithelia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

14 February 2019

Clathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

receptor-mediated endocytosis

biological process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

1 reference

14 February 2019

axonogenesis

1 reference

14 February 2019

Clathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

cell population proliferation

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O55012&geneProductId=UniProtKB:O55012

negative regulation of gene expression

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

synaptic vesicle maturation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

vesicle-mediated transport

1 reference

14 February 2019

Clathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

regulation of endocytosis

1 reference

14 February 2019

Clathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

vesicle cargo loading

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

synaptic vesicle endocytosis

SNARE motif-mediated sorting of synaptobrevin by the endocytic adaptors clathrin assembly lymphoid myeloid leukemia (CALM) and AP180 at synapses

2 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O55012&geneProductId=UniProtKB:O55012

1 January 2018

SNARE motif-mediated sorting of synaptobrevin by the endocytic adaptors clathrin assembly lymphoid myeloid leukemia (CALM) and AP180 at synapses

http://www.ebi.ac.uk/QuickGO/annotations?protein=O55012&geneProductId=UniProtKB:O55012

dendrite morphogenesis

1 reference

14 February 2019

Clathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

positive regulation of axonogenesis

1 reference

14 February 2019

Clathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

regulation of protein transport

1 reference

14 February 2019

Clathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

iron ion homeostasis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

clathrin-dependent endocytosis

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O55012&geneProductId=UniProtKB:O55012

iron ion import across plasma membrane

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O55012&geneProductId=UniProtKB:O55012

regulation of synaptic vesicle endocytosis

1 reference

14 February 2019

Clathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

positive regulation of synaptic vesicle endocytosis

1 reference

14 February 2019

SNARE motif-mediated sorting of synaptobrevin by the endocytic adaptors clathrin assembly lymphoid myeloid leukemia (CALM) and AP180 at synapses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

positive regulation of neuron death

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

positive regulation of amyloid-beta formation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

regulation of synaptic vesicle transport

1 reference

14 February 2019

Clathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

positive regulation of dendrite extension

1 reference

14 February 2019

Clathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

regulation of terminal button organization

1 reference

14 February 2019

Reduction of AP180 and CALM produces defects in synaptic vesicle size and density

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

positive regulation of synaptic vesicle clustering

1 reference

14 February 2019

Reduction of AP180 and CALM produces defects in synaptic vesicle size and density

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

endocytosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

14 February 2019

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

vesicle budding from membrane

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

synaptic vesicle budding from presynaptic endocytic zone membrane

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

synaptic vesicle endocytosis

SNARE motif-mediated sorting of synaptobrevin by the endocytic adaptors clathrin assembly lymphoid myeloid leukemia (CALM) and AP180 at synapses

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

14 February 2019

SNARE motif-mediated sorting of synaptobrevin by the endocytic adaptors clathrin assembly lymphoid myeloid leukemia (CALM) and AP180 at synapses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

iron ion import across plasma membrane

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55012

AP180 N-terminal homology (ANTH) domain

has part(s)

1 reference

ENTH domain

1 reference