Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases (Q28550876)

1

object named as

Tudor I Oprea

0 references

Angela Wandinger-Ness

14

object named as

Angela Wandinger-Ness

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author name string

Jacob O Agola

3

0 references

Yuna Guo

4

0 references

Melina Silberberg

5

0 references

Joshua Roxby

6

0 references

Anna Vestling

7

0 references

Elsa Romero

8

0 references

Zurab Surviladze

9

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Cristina Murray-Krezan

10

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Anna Waller

11

0 references

Oleg Ursu

12

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Laurie G Hudson

Creative Commons Attribution 4.0 International

13

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language of work or name

English

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publication date

2015

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published in

PLOS One

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volume

10

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issue

11

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page(s)

e0142182

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copyright license

start time

11 November 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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29 September 2017

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Drug chirality: on the mechanism of R-aryl propionic acid class NSAIDs. Epimerization in humans and the clinical implications for the use of racemates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4641600

Stereochemistry, a basis for sophisticated nonsense in pharmacokinetics and clinical pharmacology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4641600

Chirality in antirheumatic drugs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4641600

Stereoselectivity and affinity in molecular pharmacology. III. Structural aspects in the mode of action of natural and synthetic auxins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4641600

Novel Suppressive Effects of Ketotifen on Migration and Invasion of MDA-MB-231 and HT-1080 Cancer Cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4641600

High-Throughput Flow Cytometry Bead-Based Multiplex Assay for Identification of Rho GTPase Inhibitors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4641600

R-etodolac induces E-cadherin and suppresses colitis-related mouse colon tumorigenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4641600

Virtual screening approach for the identification of new Rac1 inhibitors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4641600

Characterization of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4641600

Characterization of the analgesic and anti-inflammatory activities of ketorolac and its enantiomers in the rat.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4641600

Pharmacodynamics and pharmacokinetics of the profens: enantioselectivity, clinical implications, and special reference to S( )-ibuprofen

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4641600

Stereoselective cyclooxygenase inhibition in cellular models by the enantiomers of ketoprofen

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4641600

Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal anti-inflammatory drugs.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4641600

Preclinical Enantioselective Pharmacology of (R)‐ and (S)‐ Ketorolac

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4641600

Stereoselective inhibition of inducible cyclooxygenase by chiral nonsteroidal antiinflammatory drugs

20 June 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0142182

Comparison of Shape-Matching and Docking as Virtual Screening Tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0142182

Virtual and biomolecular screening converge on a selective agonist for GPR30.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0142182

Correlation between in vitro and in vivo concentration-effect relationships of naproxen in rats and healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0142182

Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0142182

Analgesic drug use and risk of epithelial ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0142182

NSAID analgesic ketorolac used perioperatively may suppress early breast cancer relapse: particular relevance to triple negative subgroup

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0142182

Chiral kinetics and dynamics of ketorolac

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0142182

3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitor, fluvastatin, as a novel agent for prophylaxis of renal cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0142182

Overexpression of RhoA, Rac1, and Cdc42 GTPases is associated with progression in testicular cancer

21 January 2018

1 reference

12 December 2020

Etodolac selectively inhibits human prostaglandin G/H synthase 2 (PGHS-2) versus human PGHS-1

1 reference

12 December 2020

Formation of extracellular matrix-digesting invadopodia by primary aortic smooth muscle cells

1 reference

12 December 2020

Serum concentrations of salicylate and naproxen during concurrent therapy in patients with rheumatoid arthritis

1 reference

12 December 2020

Intraoperative use of ketorolac or diclofenac is associated with improved disease-free survival and overall survival in conservative breast cancer surgery

1 reference

12 December 2020

Perioperative ketorolac in high risk breast cancer patients. Rationale, feasibility and methodology of a prospective randomized placebo-controlled trial

1 reference

12 December 2020

A pharmacokinetic study of the active metabolite of nabumetone in young healthy subjects and older arthritis patients

1 reference

12 December 2020

Effect of R and S enantiomers of naproxen on aggregation and thromboxane production in human platelets

1 reference

12 December 2020

Expression of cyclooxygenase-2 and its relationship to p53 accumulation in ovarian adenocarcinomas

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0142182

Identifiers

DOI

1 reference

release_7vpqlkvvbjeu3jqjpu6sh5xouy

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/7vpqlkvvbjeu3jqjpu6sh5xouy

24 November 2022

mapped directly with Wikidata item

1528887

1 reference

1 reference

1528887

PubMed publication ID

26558612

1 reference