AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade (Q28511813)

25 January 2017

title

AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade (English)

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Kinase suppressor of ras 1

25 January 2017

main subject

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GOA release 2020-03-11

author

Anthony Pawson

4

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author name string

F. Donelson Smith

1

1 reference

25 January 2017

Lorene K. Langeberg

2

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25 January 2017

Cristina Cellurale

3

1 reference

25 January 2017

Deborah K. Morrison

5

1 reference

25 January 2017

Roger J. Davis

6

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25 January 2017

John D. Scott

7

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25 January 2017

publication date

1 December 2010

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25 January 2017

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25 January 2017

volume

12

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25 January 2017

issue

12

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25 January 2017

page(s)

1242–1249

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Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling

25 January 2017

cites work

1 reference

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Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

19 March 2017

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Differential regulation and properties of MAPKs

19 March 2017

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The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways.

19 March 2017

1 reference

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Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

19 March 2017

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Ras regulates assembly of mitogenic signalling complexes through the effector protein IMP

19 March 2017

1 reference

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Targeting RAS signalling pathways in cancer therapy

19 March 2017

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Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation

19 March 2017

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C-TAK1 regulates Ras signaling by phosphorylating the MAPK scaffold, KSR1

19 March 2017

1 reference

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AKAP-Lbc anchors protein kinase A and nucleates Galpha 12-selective Rho-mediated stress fiber formation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042953

KSR modulates signal propagation within the MAPK cascade

19 March 2017

1 reference

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Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization

19 March 2017

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https://api.crossref.org/works/10.1038/NCB2130

Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals

22 April 2017

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Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

7 April 2017

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Transformation of mammalian cells by constitutively active MAP kinase kinase

7 April 2017

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Cell signaling in space and time: where proteins come together and when they're apart

7 April 2017

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A genetically encoded fluorescent sensor of ERK activity

29 September 2017

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Domains, motifs, and scaffolds: the role of modular interactions in the evolution and wiring of cell signaling circuits.

29 September 2017

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The where's and when's of kinase anchoring

29 September 2017

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Integrating signals between cAMP and the RAS/RAF/MEK/ERK signalling pathways. Based on the anniversary prize of the Gesellschaft für Biochemie und Molekularbiologie Lecture delivered on 5 July 2003 at the Special FEBS Meeting in Brussels

29 September 2017

1 reference

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AKAP-Lbc nucleates a protein kinase D activation scaffold

29 September 2017

1 reference

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Cyclic AMP-dependent kinase regulates Raf-1 kinase mainly by phosphorylation of serine 259.

29 September 2017

1 reference

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Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo

29 September 2017

1 reference

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Inhibition of the EGF-Activated MAP Kinase Signaling Pathway by Adenosine 3′,5′-Monophosphate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042953

Protein kinase A blocks Raf-1 activity by stimulating 14-3-3 binding and blocking Raf-1 interaction with Ras.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042953

Inhibition by cAMP of Ras-Dependent Activation of Raf

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3042953

Epac: a new cAMP target and new avenues in cAMP research

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038/NCB2130

21 January 2018

Identifiers

DOI

10.1038/NCB2130

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Dimensions Publication ID

1022492534

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