Cellular localization and development of neuronal intranuclear inclusions in striatal and cortical neurons in R6/2 transgenic mice (Q28510296)

25 January 2017

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10 November 2019

title

Cellular localization and development of neuronal intranuclear inclusions in striatal and cortical neurons in R6/2 transgenic mice (English)

2 references

25 January 2017

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10 November 2019

1 reference

GOA release 2020-03-11

Calbindin 1

1 reference

GOA release 2020-03-11

Huntingtin

1 reference

GOA release 2020-03-11

1 reference

6

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10 November 2019

5

Steven Hersch

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10 November 2019

author name string

Yun-Ping Deng

2

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10 November 2019

Nobel Del Mar

4

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25 January 2017

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10 November 2019

Anton Reiner

7

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10 November 2019

Christopher A Meade

1

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10 November 2019

Francesca R Fusco

3

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10 November 2019

language of work or name

English

0 references

publication date

1 July 2002

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The Journal of Comparative Neurology

10 November 2019

published in

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volume

449

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10 November 2019

issue

3

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10 November 2019

page(s)

241-269

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Isolation and characterization of a novel gene with differential expression in benign and malignant human breast tumours

10 November 2019

cites work

1 reference

Genetics and molecular biology of Huntington's disease

21 January 2018

1 reference

Striatal and nigral neuron subpopulations in rigid Huntington's disease: implications for the functional anatomy of chorea and rigidity-akinesia

21 January 2018

1 reference

Abnormalities of striatal projection neurons and N-methyl-D-aspartate receptors in presymptomatic Huntington's disease

21 January 2018

1 reference

Preferential loss of striato-external pallidal projection neurons in presymptomatic Huntington's disease

21 January 2018

1 reference

Structure and expression of the Huntington's disease gene: evidence against simple inactivation due to an expanded CAG repeat

21 January 2018

1 reference

Extensive co-occurrence of substance P and dynorphin in striatal projection neurons: An evolutionarily conserved feature of basal ganglia organization

21 January 2018

1 reference

Interneuron Migration from Basal Forebrain to Neocortex: Dependence on Dlx Genes

21 January 2018

1 reference

Mutations of the Homeobox Genes Dlx-1 and Dlx-2 Disrupt the Striatal Subventricular Zone and Differentiation of Late Born Striatal Neurons

21 January 2018

1 reference

Immunocytochemical localization of ubiquitin in inclusion body myositis allows its light‐microscopic distinction from polymyositis

21 January 2018

1 reference

The HD mutation causes progressive lethal neurological disease in mice expressing reduced levels of huntingtin

21 January 2018

1 reference

Expanded glutamines and neurodegeneration--a gain of insight

21 January 2018

1 reference

Somatostatin and neuropeptide Y concentrations in pathologically graded cases of Huntington's disease

21 January 2018

1 reference

Intranuclear neuronal inclusions in Huntington's disease and dentatorubral and pallidoluysian atrophy: correlation between the density of inclusions and IT15 CAG triplet repeat length

21 January 2018

1 reference

The identification of a functional nuclear localization signal in the Huntington disease protein

21 January 2018

1 reference

Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice

21 January 2018

1 reference

Catalyzed reporter deposition, a novel method of signal amplification. II. Application to membrane immunoassays

21 January 2018

1 reference

Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene

21 January 2018

1 reference

Altered neurotransmitter receptor expression in transgenic mouse models of Huntington's disease

21 January 2018

1 reference

Evidence for the preferential localization of glutamate receptor-1 subunits of AMPA receptors to the dendritic spines of medium spiny neurons in rat striatum.

21 January 2018

1 reference

Parvalbumin-containing GABAergic interneurons in the rat neostriatum

21 January 2018

1 reference

Degeneration of pyramidal projection neurons in Huntington's disease cortex

21 January 2018

1 reference

Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

21 January 2018

1 reference

Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.

21 January 2018

1 reference

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

21 January 2018

1 reference

Are neuronal intranuclear inclusions the common neuropathology of triplet-repeat disorders with polyglutamine-repeat expansions?

21 January 2018

1 reference

Cannabinoid receptor messenger RNA levels decrease in a subset of neurons of the lateral striatum, cortex and hippocampus of transgenic Huntington's disease mice

21 January 2018

1 reference

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

21 January 2018

1 reference

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

21 January 2018

1 reference

Nuclear targeting sequences--a consensus?

21 January 2018

1 reference

Analysis of the subcellular localization of huntingtin with a set of rabbit polyclonal antibodies in cultured mammalian cells of neuronal origin: comparison with the distribution of huntingtin in Huntington's disease autopsy brain

21 January 2018

1 reference

Inactivation of the mouse Huntington's disease gene homolog Hdh

21 January 2018

1 reference

Selective sparing of a class of striatal neurons in Huntington's disease

21 January 2018

1 reference

Topography of enkephalin, substance P and acetylcholinesterase staining in Huntington's disease striatum

21 January 2018

1 reference

Sparing of acetylcholinesterase-containing striatal neurons in Huntington's disease

21 January 2018

1 reference

Polyglutamine expansions: proteolysis, chaperones, and the dangers of promiscuity

21 January 2018

1 reference

Relative survival of striatal projection neurons and interneurons after intrastriatal injection of quinolinic acid in rats

21 January 2018

1 reference

Calretinin is largely localized to a unique population of striatal interneurons in rats

21 January 2018

1 reference

Colocalization of somatostatin, neuropeptide Y, neuronal nitric oxide synthase and NADPH-diaphorase in striatal interneurons in rats.

21 January 2018

1 reference

Age-Dependent Differences in Survival of Striatal Somatostatin–NPY–NADPH–Diaphorase-Containing Interneurons versus Striatal Projection Neurons after Intrastriatal Injection of Quinolinic Acid in Rats

21 January 2018

1 reference

Relative resistance of striatal neurons containing calbindin or parvalbumin to quinolinic acid-mediated excitotoxicity compared to other striatal neuron types

21 January 2018

1 reference

Distribution of striatonigral and striatopallidal peptidergic neurons in both patch and matrix compartments: an in situ hybridization histochemistry and fluorescent retrograde tracing study

21 January 2018

1 reference

Differential distribution of the normal and mutated forms of huntingtin in the human brain

21 January 2018

1 reference

Neuronal distribution of intranuclear inclusions in Huntington's disease with adult onset.

21 January 2018

1 reference

Trinucleotide instability: a repeating theme in human inherited disorders

21 January 2018

1 reference

Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies

21 January 2018

1 reference

The influence of huntingtin protein size on nuclear localization and cellular toxicity.

21 January 2018

1 reference

Neuronal loss in layers V and VI of cerebral cortex in Huntington's disease

21 January 2018

1 reference

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

21 January 2018

1 reference

Spinocerebellar ataxia type 7 (SCA7): a neurodegenerative disorder with neuronal intranuclear inclusions

21 January 2018

1 reference

Characterization and localization of the Huntington disease gene product

21 January 2018

1 reference

Amyloid formation by mutant huntingtin: threshold, progressivity and recruitment of normal polyglutamine proteins

21 January 2018

1 reference

Mechanisms of striatal pattern formation: conservation of mammalian compartmentalization

21 January 2018

1 reference

Peptides containing glutamine repeats as substrates for transglutaminase-catalyzed cross-linking: relevance to diseases of the nervous system

21 January 2018

1 reference

Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells

21 January 2018

1 reference

Parvalbumin-immunoreactive neurons in the rat neostriatum: a light and electron microscopic study

21 January 2018

1 reference

Calbindin D28K as a marker for the degeneration of the striatonigral pathway in Huntington's disease

21 January 2018

1 reference

Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice

21 January 2018

1 reference

Intranuclear inclusions in subtypes of striatal neurons in Huntington's disease transgenic mice

21 January 2018

1 reference

Huntingtin immunoreactivity in the rat neostriatum: differential accumulation in projection and interneurons

21 January 2018

1 reference

Huntington's disease gene: regional and cellular expression in brain of normal and affected individuals

21 January 2018

1 reference

Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity

21 January 2018

1 reference

Aggregation of N-terminal huntingtin is dependent on the length of its glutamine repeats

21 January 2018

1 reference

Huntington's disease gene (IT15) is widely expressed in human and rat tissues

21 January 2018

1 reference

Neurological abnormalities in a knock-in mouse model of Huntington's disease

21 January 2018

1 reference

Expanding our understanding of polyglutamine diseases through mouse models

21 January 2018

1 reference

A cellular model that recapitulates major pathogenic steps of Huntington's disease

21 January 2018

1 reference

Pathological mechanisms in Huntington's disease and other polyglutamine expansion diseases

21 January 2018

1 reference

Decreased expression of striatal signaling genes in a mouse model of Huntington's disease

21 January 2018

1 reference

Distribution of inclusions in neuronal nuclei and dystrophic neurites in Huntington disease brain

21 January 2018

1 reference

Significant loss of pyramidal neurons in the angular gyrus of patients with Huntington's disease

21 January 2018

1 reference

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

21 January 2018

1 reference

Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates

21 January 2018

1 reference

Decrease in striatal enkephalin mRNA in mouse models of Huntington's disease

21 January 2018

1 reference

Progressive depletion of complexin II in a transgenic mouse model of Huntington's disease

21 January 2018

1 reference

Progressive formation of inclusions in the striatum and hippocampus of mice transgenic for the human Huntington's disease mutation

21 January 2018

1 reference

A molecular investigation of true dominance in Huntington's disease

21 January 2018

1 reference

Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes

21 January 2018

1 reference

Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

21 January 2018

1 reference

Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3.

21 January 2018

1 reference

Differential expression of normal and mutant Huntington's disease gene alleles

21 January 2018

1 reference

Glutamine repeats and neurodegenerative diseases: molecular aspects

21 January 2018

1 reference

Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases

21 January 2018

1 reference

Recent advances on the pathogenesis of Huntington's disease

21 January 2018

1 reference

Evidence for a recruitment and sequestration mechanism in Huntington's disease

21 January 2018

1 reference

Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA.

21 January 2018

1 reference

Recent advances in understanding the pathogenesis of Huntington's disease

21 January 2018

1 reference

Differential loss of striatal projection neurons in Huntington disease

21 January 2018

1 reference

Preferential loss of preproenkephalin versus preprotachykinin neurons from the striatum of Huntington's disease patients

21 January 2018

1 reference

Intranuclear Neuronal Inclusions: A Common Pathogenic Mechanism for Glutamine-Repeat Neurodegenerative Diseases?

21 January 2018

1 reference

Evidence for a preferential loss of enkephalin immunoreactivity in the external globus pallidus in low grade Huntington's disease using high resolution image analysis

21 January 2018

1 reference

Huntingtin localization in brains of normal and Huntington's disease patients

21 January 2018

1 reference

Axonal transport of N-terminal huntingtin suggests early pathology of corticostriatal projections in Huntington disease

21 January 2018

1 reference

Early and progressive accumulation of reactive microglia in the Huntington disease brain

21 January 2018

1 reference

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

21 January 2018

1 reference

Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin

21 January 2018

1 reference

Neurobiology of Huntington's disease

21 January 2018

1 reference

Widespread expression of Huntington's disease gene (IT15) protein product

21 January 2018

1 reference

A Huntington's disease CAG expansion at the murine Hdh locus is unstable and associated with behavioural abnormalities in mice

21 January 2018

1 reference

Huntington's disease intranuclear inclusions contain truncated, ubiquitinated huntingtin protein

21 January 2018

1 reference

Evidence for neuronal degeneration and dendritic plasticity in cortical pyramidal neurons of Huntington's disease: a quantitative Golgi study.

21 January 2018

1 reference

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

21 January 2018

1 reference

The cortical lesion of Huntington's disease: further neurochemical characterization, and reproduction of some of the histological and neurochemical features by N-methyl-D-aspartate lesions of rat cortex

21 January 2018

1 reference

Ultrastructure of Neurofibrillary Tangles in Steele-Richardson-Olszewski Syndrome

21 January 2018

1 reference

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

21 January 2018

1 reference

Full length huntingtin is not detected in intranuclear inclusions in Huntington's disease brain

21 January 2018

1 reference

Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form

21 January 2018

1 reference

Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease

21 January 2018

1 reference

21 January 2018

1 reference

Homozygotes for Huntington's disease

21 January 2018

1 reference

Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice

21 January 2018

1 reference

Young neurons from medial ganglionic eminence disperse in adult and embryonic brain

21 January 2018

1 reference

tRNA transport from the nucleus in a eukaryotic cell: carrier-mediated translocation process

21 January 2018

1 reference

Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue

21 January 2018

1 reference

Of molecular interactions, mice and mechanisms

21 January 2018

1 reference

Synthetic peptides as nuclear localization signals

21 January 2018

1 reference

cFos immunoreactivity is enhanced with biotin amplification

21 January 2018

1 reference

7 January 2021

Catalyzed reporter deposition, a novel method of signal amplification. Application to immunoassays

1 reference

7 January 2021

Morphometric demonstration of atrophic changes in the cerebral cortex, white matter, and neostriatum in Huntington's disease

1 reference

7 January 2021

Quantification without pontification: Choosing a method for counting objects in sectioned tissues

1 reference

7 January 2021

The fatal attraction of polyglutamine-containing proteins.

1 reference

7 January 2021

A simple and sensitive antigen retrieval method for free-floating and slide-mounted tissue sections

1 reference

7 January 2021

Neuronal intranuclear inclusions in polyglutamine diseases: nuclear weapons or nuclear fallout?

1 reference

7 January 2021

Nuclear inclusions in glutamine repeat disorders: are they pernicious, coincidental, or beneficial?

1 reference

7 January 2021

Mitochondrial dysfunction and free radical damage in the Huntington R6/2 transgenic mouse

1 reference

7 January 2021

Neuropathological classification of Huntington's disease

1 reference

7 January 2021

Identifiers

DOI

10.1002/CNE.10295

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12115678 AND SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017