Essential role of PDK1 in regulating endothelial cell migration (Q28509286)

24 January 2017

title

Essential role of PDK1 in regulating endothelial cell migration (English)

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3-phosphoinositide dependent protein kinase 1

24 January 2017

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GOA release 2020-03-11

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Luca Primo

1

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24 January 2017

Laura di Blasio

2

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24 January 2017

Cristina Roca

3

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24 January 2017

Sara Droetto

4

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24 January 2017

Roberto Piva

5

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24 January 2017

Brian Schaffhausen

6

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24 January 2017

Federico Bussolino

7

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24 January 2017

language of work or name

English

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publication date

26 March 2007

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24 January 2017

published in

Journal of Cell Biology

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24 January 2017

volume

176

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24 January 2017

issue

7

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24 January 2017

page(s)

1035–1047

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SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity

24 January 2017

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The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB.

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19 March 2017

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Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2

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19 March 2017

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

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7 April 2017

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Stable interaction between alpha5beta1 integrin and Tie2 tyrosine kinase receptor regulates endothelial cell response to Ang-1.

7 April 2017

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Signaling to Cytoskeletal Dynamics during Chemotaxis

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Membrane localization of 3-phosphoinositide-dependent protein kinase-1 stimulates activities of Akt and atypical protein kinase C but does not stimulate glucose transport and glycogen synthesis in 3T3-L1 adipocytes

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Role of S6 phosphorylation and S6 kinase in cell growth

29 September 2017

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29 September 2017

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Polarization of chemoattractant receptor signaling during neutrophil chemotaxis

29 September 2017

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Quantitative elucidation of a distinct spatial gradient-sensing mechanism in fibroblasts

29 September 2017

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Ablation of oncogenic ALK is a viable therapeutic approach for anaplastic large-cell lymphomas

2 June 2018

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2 June 2018

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2 June 2018

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Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth

2 June 2018

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Identification of CD36 molecular features required for its in vitro angiostatic activity

2 June 2018

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Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis

27 November 2018

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Tumor suppressor PTEN mediates sensing of chemoattractant gradients.

27 November 2018

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Control of cell polarity and chemotaxis by Akt/PKB and PI3 kinase through the regulation of PAKa

27 November 2018

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Inhibition of PDK-1 activity causes a reduction in cell proliferation and survival

27 November 2018

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Vascular endothelial growth factor-stimulated actin reorganization and migration of endothelial cells is regulated via the serine/threonine kinase Akt

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12 December 2020

The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells

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Vasculogenesis and angiogenesis in embryonic-stem-cell-derived embryoid bodies

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Embryonic stem cells differentiate in vitro to endothelial cells through successive maturation steps

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Identifiers

DOI

10.1083/JCB.200607053

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