Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability (Q28508931)

24 January 2017

title

Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability (English)

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24 January 2017

main subject

Thymine DNA glycosylase

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GOA release 2020-03-11

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Christophe Kunz

2

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Primo Schär

object named as

Primo Schär

14

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Jim Selfridge

object named as

Jim Selfridge

3

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Adrian Peter Bird

object named as

Adrian Bird

13

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author name string

Daniel Cortázar

1

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24 January 2017

Teresa Lettieri

4

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Yusuke Saito

5

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24 January 2017

Eilidh MacDougall

6

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Annika Wirz

7

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David Schuermann

8

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24 January 2017

Angelika L. Jacobs

9

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Fredy Siegrist

10

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Roland Steinacher

11

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Josef Jiricny

12

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24 January 2017

language of work or name

English

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publication date

17 February 2011

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24 January 2017

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24 January 2017

volume

470

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24 January 2017

issue

7334

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24 January 2017

page(s)

419–423

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A new class of uracil-DNA glycosylases related to human thymine-DNA glycosylase

24 January 2017

cites work

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Retinoic acid receptors interact physically and functionally with the T:G mismatch-specific thymine-DNA glycosylase

21 January 2018

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T:G mismatch-specific thymine-DNA glycosylase potentiates transcription of estrogen-regulated genes through direct interaction with estrogen receptor alpha

21 January 2018

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Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription

21 January 2018

1 reference

Association of Dnmt3a and thymine DNA glycosylase links DNA methylation with base-excision repair.

21 January 2018

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Overexpression of 5-methylcytosine DNA glycosylase in human embryonic kidney cells EcR293 demethylates the promoter of a hormone-regulated reporter gene

21 January 2018

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Cyclical DNA methylation of a transcriptionally active promoter

21 January 2018

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Transient cyclical methylation of promoter DNA.

21 January 2018

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The enigmatic thymine DNA glycosylase

21 January 2018

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DNA repair in mammalian cells: Base excision repair: the long and short of it.

21 January 2018

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Polycomb complexes repress developmental regulators in murine embryonic stem cells

21 January 2018

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Silencing of Peroxiredoxin 2 and aberrant methylation of 33 CpG islands in putative promoter regions in human malignant melanomas.

21 January 2018

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Separating substrate recognition from base hydrolysis in human thymine DNA glycosylase by mutational analysis

21 January 2018

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XRCC1 and DNA strand break repair

21 January 2018

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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

21 January 2018

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MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis

21 January 2018

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MLL protects CpG clusters from methylation within the Hoxa9 gene, maintaining transcript expression.

21 January 2018

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Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II.

21 January 2018

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Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes

21 January 2018

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5-methylcytosine-DNA glycosylase activity is present in a cloned G/T mismatch DNA glycosylase associated with the chicken embryo DNA demethylation complex

21 January 2018

1 reference

Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming

21 January 2018

1 reference

DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45.

21 January 2018

1 reference

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

21 January 2018

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Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

21 January 2018

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Base excision by thymine DNA glycosylase mediates DNA-directed cytotoxicity of 5-fluorouracil

21 January 2018

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Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells

21 January 2018

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Deoxyribonucleic Acid Methyl Transferases 3a and 3b Associate with the Nuclear Orphan Receptor COUP-TFI during Gene Activation

21 January 2018

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Generation of a defined and uniform population of CNS progenitors and neurons from mouse embryonic stem cells

21 January 2018

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Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer

21 January 2018

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https://pubmed.ncbi.nlm.nih.gov/21278727