A serotonin and melanocortin circuit mediates D-fenfluramine anorexia (Q28506385)

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21048120 AND SRC:MED&resulttype=core&format=json

15 January 2020

title

A serotonin and melanocortin circuit mediates D-fenfluramine anorexia (English)

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21048120 AND SRC:MED&resulttype=core&format=json

5-hydroxytryptamine (serotonin) receptor 2C

15 January 2020

main subject

serotonin

0 references

1 reference

GOA release 2020-03-11

author

Andrew R. Zinn

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21048120 AND SRC:MED&resulttype=core&format=json

15 January 2020

Jason Graham Anderson

4

object named as

Jason G Anderson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21048120 AND SRC:MED&resulttype=core&format=json

15 January 2020

author name string

Yong Xu

1

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21048120 AND SRC:MED&resulttype=core&format=json

15 January 2020

Nina Balthasar

5

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21048120 AND SRC:MED&resulttype=core&format=json

15 January 2020

Juli E Jones

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21048120 AND SRC:MED&resulttype=core&format=json

15 January 2020

Danielle A Lauzon

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21048120 AND SRC:MED&resulttype=core&format=json

15 January 2020

Lora K Heisler

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21048120 AND SRC:MED&resulttype=core&format=json

15 January 2020

Bradford B Lowell

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21048120 AND SRC:MED&resulttype=core&format=json

15 January 2020

Joel K Elmquist

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21048120 AND SRC:MED&resulttype=core&format=json

15 January 2020

language of work or name

English

0 references

publication date

1 November 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21048120 AND SRC:MED&resulttype=core&format=json

15 January 2020

published in

Journal of Neuroscience

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21048120 AND SRC:MED&resulttype=core&format=json

15 January 2020

volume

30

2 references

24 January 2017

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15 January 2020

issue

44

2 references

24 January 2017

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15 January 2020

page(s)

14630-14634

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21048120 AND SRC:MED&resulttype=core&format=json

Pharmacological targeting of the serotonergic system for the treatment of obesity

15 January 2020

cites work

1 reference

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A frameshift mutation in human MC4R is associated with a dominant form of obesity

19 March 2017

1 reference

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Valvular heart disease associated with fenfluramine-phentermine

19 March 2017

1 reference

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Targeted disruption of the melanocortin-4 receptor results in obesity in mice

19 March 2017

1 reference

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Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain

19 March 2017

1 reference

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Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance

19 March 2017

1 reference

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5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasis

29 September 2017

1 reference

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Serotonin 5-HT2C receptor agonist promotes hypophagia via downstream activation of melanocortin 4 receptors

29 September 2017

1 reference

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Serotonin 2C receptor agonists improve type 2 diabetes via melanocortin-4 receptor signaling pathways

29 September 2017

1 reference

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Inactivation of 5-HT(2C) receptors potentiates consequences of serotonin reuptake blockade

29 September 2017

1 reference

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Sim1 gene dosage modulates the homeostatic feeding response to increased dietary fat in mice

29 September 2017

1 reference

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Sim1 haploinsufficiency causes hyperphagia, obesity and reduction of the paraventricular nucleus of the hypothalamus

29 September 2017

1 reference

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Profound obesity associated with a balanced translocation that disrupts the SIM1 gene

29 September 2017

1 reference

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Neurobiology of an anorectic drug: fenfluramine

29 September 2017

1 reference

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5-HT1c receptor is a prominent serotonin receptor subtype in the central nervous system

29 September 2017

1 reference

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Absence of fenfluramine-induced anorexia and reduced c-Fos induction in the hypothalamus and central amygdaloid complex of serotonin 1B receptor knock-out mice.

29 September 2017

1 reference

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Serotonin 5-hydroxytryptamine2C receptor signaling in hypothalamic proopiomelanocortin neurons: role in energy homeostasis in females

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466475

Serotonin Reciprocally Regulates Melanocortin Neurons to Modulate Food Intake

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466475

Divergence of melanocortin pathways in the control of food intake and energy expenditure

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466475

The melanocortin system as a central integrator of direct and indirect controls of food intake.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466475

( )-Fenfluramine and its major metabolite, ( )-norfenfluramine, are potent substrates for norepinephrine transporters

27 November 2018

1 reference

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Activation of central melanocortin pathways by fenfluramine

27 November 2018

1 reference

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Differential effects of d-fenfluramine, l-fenfluramine and d-amphetamine on the microstructure of human eating behaviour

27 November 2018

1 reference

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Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene

27 November 2018

1 reference

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Serotoninergic endings on VIP-neurons in the suprachiasmatic nucleus and on ACTH-neurons in the arcuate nucleus of the rat hypothalamus. A combination of high resolution autoradiography and electron microscopic immunocytochemistry

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21048120

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/21048120

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Reduced satiating effect of d -fenfluramine in serotonin 5-HT 2C receptor mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21048120

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1523/JNEUROSCI.5412-09.2010

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21048120 AND SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21048120 AND SRC:MED&resulttype=core&format=json

15 January 2020

2 references

24 January 2017