Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8 (Q28504869)

24 January 2017

title

Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8 (English)

1 reference

24 January 2017

1 reference

GOA release 2020-03-11

Myosin XVA

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Epidermal growth factor receptor pathway substrate 8

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Pier Paolo Di Fiore

6

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Giorgio Scita

7

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Andrea Disanza

2

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Uri Manor

object named as

Uri Manor

1

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Leonardo R Andrade

object named as

Leonardo Andrade

4

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author name string

M'Hamed Grati

3

1 reference

24 January 2017

Harrison Lin

5

1 reference

24 January 2017

Bechara Kachar

8

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24 January 2017

language of work or name

English

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publication date

25 January 2011

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24 January 2017

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24 January 2017

volume

21

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24 January 2017

issue

2

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24 January 2017

page(s)

167–172

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Molecular basis for the dual function of Eps8 on actin dynamics: bundling and capping

24 January 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

Twinfilin 2 regulates actin filament lengths in cochlear stereocilia

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

Dynamic length regulation of sensory stereocilia

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

Regulation of cell shape by Cdc42 is mediated by the synergic actin-bundling activity of the Eps8-IRSp53 complex

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

A new compartment at stereocilia tips defined by spatial and temporal patterns of myosin IIIa expression

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

Increased ethanol resistance and consumption in Eps8 knockout mice correlates with altered actin dynamics

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

Whirlin complexes with p55 at the stereocilia tip during hair cell development.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

The DFNB31 gene product whirlin connects to the Usher protein network in the cochlea and retina by direct association with USH2A and VLGR1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

A human protein-protein interaction network: a resource for annotating the proteome

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

Eps8 controls actin-based motility by capping the barbed ends of actin filaments

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

An actin molecular treadmill and myosins maintain stereocilia functional architecture and self-renewal

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

Defects in whirlin, a PDZ domain molecule involved in stereocilia elongation, cause deafness in the whirler mouse and families with DFNB31

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

EPS8 and E3B1 transduce signals from Ras to Rac

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

Nonsyndromic Deafness DFNA1 Associated with Mutation of a Human Homolog of the Drosophila Gene diaphanous

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

MyosinVIIa interacts with Twinfilin-2 at the tips of mechanosensory stereocilia in the inner ear.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

Fast adaptation and Ca2 sensitivity of the mechanotransducer require myosin-XVa in inner but not outer cochlear hair cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

Myosin IIIa boosts elongation of stereocilia by transporting espin 1 to the plus ends of actin filaments

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

Protein localization by actin treadmilling and molecular motors regulates stereocilia shape and treadmilling rate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

Whirler mutant hair cells have less severe pathology than shaker 2 or double mutants

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

When size matters: the dynamic regulation of stereocilia lengths

29 September 2017

1 reference

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Association of unconventional myosin MYO15 mutations with human nonsyndromic deafness DFNB3.

29 September 2017

1 reference

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A novel form of motility in filopodia revealed by imaging myosin-X at the single-molecule level

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

Correction of deafness in shaker-2 mice by an unconventional myosin in a BAC transgene.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

Regulation of otic vesicle and hair cell stereocilia morphogenesis by Ena/VASP-like (Evl) in Xenopus

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040242

10.1016/J.CUB.2010.12.046

27 November 2018

Identifiers

DOI

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