Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice (Q28504500)

24 January 2017

title

Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice (English)

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24 January 2017

0 references

1 reference

B cell leukemia/lymphoma 2

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BCL2-associated X protein

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BCL2-antagonist/killer 1

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BCL2-like 2

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BH3 interacting domain death agonist

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BCL2-associated agonist of cell death

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Lactate dehydrogenase A

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cytochrome c oxidase subunit 4I2

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author name string

Girish V. Putcha

1

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24 January 2017

Charles A. Harris

2

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24 January 2017

Krista L. Moulder

3

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24 January 2017

Rachael M. Easton

4

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24 January 2017

Craig B. Thompson

5

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24 January 2017

Eugene M. Johnson

6

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24 January 2017

language of work or name

English

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publication date

29 April 2002

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24 January 2017

published in

Journal of Cell Biology

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24 January 2017

volume

157

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24 January 2017

issue

3

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24 January 2017

page(s)

441–453

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

24 January 2017

cites work

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Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis

19 March 2017

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19 March 2017

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Structure of Bax: coregulation of dimer formation and intracellular localization

19 March 2017

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Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

19 March 2017

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Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

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Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

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19 March 2017

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19 March 2017

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

19 March 2017

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19 March 2017

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The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9

19 March 2017

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Bim: a novel member of the Bcl-2 family that promotes apoptosis

19 March 2017

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

19 March 2017

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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

19 March 2017

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harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L)

19 March 2017

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BID: a novel BH3 domain-only death agonist

19 March 2017

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BAX is required for neuronal death after trophic factor deprivation and during development

19 March 2017

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

19 March 2017

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19 March 2017

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BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

19 March 2017

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Characterization of XIAP-deficient mice

29 September 2017

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Inhibition of apoptotic signaling cascades causes loss of trophic factor dependence during neuronal maturation

29 September 2017

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Programmed cell death of embryonic motoneurons triggered through the Fas death receptor

29 September 2017

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Caspase activation: the induced-proximity model

29 September 2017

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Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death.

29 September 2017

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Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases

29 September 2017

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The contrasting roles of ICE family proteases and interleukin-1beta in apoptosis induced by trophic factor withdrawal and by copper/zinc superoxide dismutase down-regulation

29 September 2017

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Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.

29 September 2017

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Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

29 September 2017

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Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation

29 September 2017

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CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons

29 September 2017

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Blocking cytochrome c activity within intact neurons inhibits apoptosis.

2 June 2018

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Molecular Cloning of a Novel Polypeptide, DP5, Induced during Programmed Neuronal Death

2 June 2018

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Metabolic and genetic analyses of apoptosis in potassium/serum-deprived rat cerebellar granule cells

2 June 2018

1 reference

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Cascade of caspase activation in potassium-deprived cerebellar granule neurons: targets for treatment with peptide and protein inhibitors of apoptosis

2 June 2018

1 reference

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Neuron-specific Bcl-2 homology 3 domain-only splice variant of Bak is anti-apoptotic in neurons, but pro-apoptotic in non-neuronal cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173286

Characterization of the execution pathway of developing motoneurons deprived of trophic support.

27 November 2018

1 reference

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Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173286

Endogenous bax translocation in SH-SY5Y human neuroblastoma cells and cerebellar granule neurons undergoing apoptosis

27 November 2018

1 reference

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Death-signalling cascade in mouse cerebellar granule neurons

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173286

Placement of the BCL2 family member BAX in the death pathway of sympathetic neurons activated by trophic factor deprivation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173286

Comparison of apoptosis in wild-type and Fas-resistant cells: chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions

27 November 2018

1 reference

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Checkpoints of dueling dimers foil death wishes

27 November 2018

1 reference

12 December 2020

Evidence of a novel event during neuronal death: development of competence-to-die in response to cytoplasmic cytochrome c

1 reference

12 December 2020

BAX translocation is a critical event in neuronal apoptosis: regulation by neuroprotectants, BCL-2, and caspases

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12 December 2020

BH3-only Bcl-2 family members are coordinately regulated by the JNK pathway and require Bax to induce apoptosis in neurons

1 reference

12 December 2020

Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation

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12 December 2020

Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells

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12 December 2020

Nonionic detergents induce dimerization among members of the Bcl-2 family

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12 December 2020

Involvement of caspases in sympathetic neuron apoptosis

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12 December 2020

Techniques in the tissue culture of rat sympathetic neurons

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12 December 2020

Nerve growth factor regulates sympathetic ganglion cell morphology and survival in the adult mouse

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12 December 2020

Identifiers

DOI

10.1083/JCB.200110108

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PMC publication ID

2173286

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1 reference