Detailed Regulatory Mechanism of the Interaction between ZO-1 PDZ2 and Connexin43 Revealed by MD Simulations (Q28478719)

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0021527

molecular dynamics simulation

6 December 2024

main subject

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21731774

6 December 2024

author name string

Fei Xiao

1

0 references

Jingwei Weng

2

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Kangnian Fan

3

0 references

Wenning Wang

4

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language of work or name

English

0 references

publication date

2011

0 references

23 June 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21731774

full work available at URL

6 December 2024

https://doi.org/10.1371/journal.pone.0021527

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21731774

https://europepmc.org/articles/PMC3121883

6 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21731774

https://europepmc.org/articles/PMC3121883?pdf=render

6 December 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21731774

http://dx.plos.org/10.1371/journal.pone.0021527

6 December 2024

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0021527

6 December 2024

0 references

6

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issue

6

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page(s)

e21527

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copyright license

Creative Commons Attribution 4.0 International

start time

23 June 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Domain-swapped dimerization of ZO-1 PDZ2 generates specific and regulatory connexin43-binding sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

A Novel GTPase-activating Protein for Rho Interacts with a PDZ Domain of the Protein-tyrosine Phosphatase PTPL1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

PDZ domains: targeting signalling molecules to sub-membranous sites

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

ZO-1, DlgA and PSD-95/SAP90: homologous proteins in tight, septate and synaptic cell junctions

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

FAP-1: a protein tyrosine phosphatase that associates with Fas

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

Clustering of Shaker-type K channels by interaction with a family of membrane-associated guanylate kinases

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

Structural changes in the carboxyl terminus of the gap junction protein connexin43 indicates signaling between binding domains for c-Src and zonula occludens-1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

Recognition of unique carboxyl-terminal motifs by distinct PDZ domains

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

PDZ domain proteins of synapses

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

Akt phosphorylates Connexin43 on Ser373, a "mode-1" binding site for 14-3-3.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

Regulation of connexin43 gap junctional communication by phosphatidylinositol 4,5-bisphosphate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

ZO-1 is required for protein kinase C gamma-driven disassembly of connexin 43

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

Thermodynamic basis for promiscuity and selectivity in protein-protein interactions: PDZ domains, a case study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

Zonula occludens-1 alters connexin43 gap junction size and organization by influencing channel accretion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

Connexin phosphorylation as a regulatory event linked to gap junction channel assembly

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

Organization of signaling complexes by PDZ-domain scaffold proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

PDZ domains-glue and guide.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

Direct association of the gap junction protein connexin-43 with ZO-1 in cardiac myocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

Protein-protein interactions: PDZ domain networks

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

PDZs and receptor/channel clustering: rounding up the latest suspects

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

Regulation of the TRP Ca2 channel by INAD in Drosophila photoreceptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

PDZ Domains and the Formation of Protein Networks at the Plasma Membrane

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

Interaction of ion channels and receptors with PDZ domain proteins

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

PDZ domains bind carboxy-terminal sequences of target proteins

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121883

LET-23 receptor localization by the cell junction protein LIN-7 during C. elegans vulval induction

2 June 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0021527

PDZ proteins organize synaptic signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0021527

Signals mediating ion channel clustering at the neuromuscular junction

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0021527

Molecular mechanisms of glutamate receptor clustering at excitatory synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0021527

Identification and functional analysis of novel phosphorylation sites in Cx43 in rat primary granulosa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0021527

All-atom Monte Carlo approach to protein-peptide binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0021527

GROMACS: A message-passing parallel molecular dynamics implementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0021527

GROMACS 3.0: a package for molecular simulation and trajectory analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0021527

High‐Temperature Equation of State by a Perturbation Method. I. Nonpolar Gases

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0021527

Molecular dynamics with coupling to an external bath

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0021527

Identification of specificity and promiscuity of PDZ domain interactions through their dynamic behavior

21 January 2018

1 reference

PubMed

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Energetics of nucleophile activation in a protein tyrosine phosphatase

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LINCS: A linear constraint solver for molecular simulations

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